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"Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs."--

Proteins --- Structure. --- Intrinsically Disordered Proteins --- Carrier Proteins. --- Protein Conformation --- physiology. --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Binding Protein --- Binding Proteins --- Transport Proteins --- Protein, Binding --- Proteins, Binding --- Proteins, Carrier --- Proteins, Transport --- Protein Binding --- Receptors, Transferrin --- Carrier Protein --- Transport Protein --- Protein, Carrier --- Protein, Transport

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Molecular biology --- Molecular structure --- Cytology --- Protein folding --- RNA --- Biomolecules --- Conformation --- Design --- Biologie moléculaire --- Structure moléculaire --- Cytologie --- Molecular Structure --- Cells --- Protein Conformation --- Protein Engineering --- Protein Folding --- ultrastructure --- Molecular Structure. --- Protein Conformation. --- Protein Engineering. --- Protein Folding. --- ultrastructure. --- Protein Folding, Globular --- Folding, Globular Protein --- Folding, Protein --- Foldings, Globular Protein --- Foldings, Protein --- Globular Protein Folding --- Globular Protein Foldings --- Protein Foldings --- Protein Foldings, Globular --- Genetic Engineering, Protein --- Proteins, Genetic Engineering --- Genetic Engineering of Proteins --- Engineering, Protein --- Engineering, Protein Genetic --- Protein Genetic Engineering --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Structure, Molecular --- Molecular Structures --- Structures, Molecular --- Biological molecules --- Ribonucleic acid --- Ribose nucleic acid --- Folding of proteins --- Proteins --- Folding --- Cytology. --- Molecular biology. --- Molecular structure. --- Protein folding. --- Proteostasis --- Protein Multimerization --- Intrinsically Disordered Proteins --- Genetic Engineering --- Directed Molecular Evolution --- DNA Shuffling --- Molecular Farming --- Models, Molecular --- Chemical structure --- Structural bioinformatics --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Cell biology --- Cellular biology --- Biology --- Cytologists --- Molecules --- Nucleic acids --- Ribose --- Biologie moléculaire --- Structure moléculaire --- Cell --- Cell Biology --- Protein engineering. --- Protéines --- ARN --- Structure moléculaire. --- Technologie des protéines. --- molecular structure. --- Conformation. --- Repliement --- Protein design --- Biochemical engineering --- Genetic engineering --- Protein conformation --- Enginyeria de proteïnes --- Biologia molecular --- Estructura molecular --- Citologia