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Geneticists and molecular biologists have been interested in quantifying genes and their products for many years and for various reasons (Bishop, 1974). Early molecular methods were based on molecular hybridization, and were devised shortly after Marmur and Doty (1961) first showed that denaturation of the double helix could be reversed - that the process of molecular reassociation was exquisitely sequence dependent. Gillespie and Spiegelman (1965) developed a way of using the method to titrate the number of copies of a probe within a target sequence in which the target sequence was fixed to a membrane support prior to hybridization with the probe - typically a RNA. Thus, this was a precursor to many of the methods still in use, and indeed under development, today. Early examples of the application of these methods included the measurement of the copy numbers in gene families such as the ribosomal genes and the immunoglo­ bulin family. Amplification of genes in tumors and in response to drug treatment was discovered by this method. In the same period, methods were invented for estimating gene num­ bers based on the kinetics of the reassociation process - the so-called Cot analysis. This method, which exploits the dependence of the rate of reassociation on the concentration of the two strands, revealed the presence of repeated sequences in the DNA of higher eukaryotes (Britten and Kohne, 1968). An adaptation to RNA, Rot analysis (Melli and Bishop, 1969), was used to measure the abundance of RNAs in a mixed population.

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Biochemical Engineering Fundamentals, 2/e, combines contemporary engineering science with relevant biological concepts in a comprehensive introduction to biochemical engineering. The biological background provided enables students to comprehend the major problems in biochemical engineering and formulate effective solutions.

Génie biochimique --- 66.098 --- Bio-process engineering --- Bioprocess engineering --- Biological processes. Biotechnology --- 66.098 Biological processes. Biotechnology --- Génie biochimique --- Biochemical engineering --- 66.01 --- Biochemistry --- Biotechnology --- Chemical engineering --- 66.01 Chemical engineering and processing principles. Process design and control. Plant layout and services. Materials, properties etc. --- Chemical engineering and processing principles. Process design and control. Plant layout and services. Materials, properties etc. --- Chemical engineering and processing principles. Process design and control. Plant layout and services. Materials, properties etc --- General biochemistry --- biotechnologie --- biochemie --- biochemistry --- bioengineering --- Biochemical engineering. --- Basic Sciences. Chemistry --- Biochemistry.

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Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences as well as covers the commercial, political, ethical, legal, and societal aspects of this research. The first function is fulfilled by the peer-reviewed research section, the second by the expository efforts in the front of the journal. We provide researchers with news about business; we provide the business community with news about research developments. The core areas in which we are actively seeking research papers include: molecular engineering of nucleic acids and proteins; molecular therapy (therapeutics genes, antisense, siRNAs, aptamers, and DNAzymes, ribozymes, peptides, proteins); large-scale biology (genomics, functional genomics, proteomics, structural genomics, metabolomics, etc.); computational biology (algorithms and modeling), regenerative medicine (stem cells, tissue engineering, biomaterials); imaging technology; analytical biotechnology (sensors/detectors for analytes/macromolecules), applied immunology (antibody engineering, xenotransplantation, T-cell therapies); food and agricultural biotechnology; and environmental biotechnology.

Biochemical engineering --- Zoology --- biotechnologie --- Biotechnology --- Molecular biology --- bioengineering --- Génie biochimique --- Biotechnologie --- periodicals --- Periodicals --- Périodiques --- Biotechnology. --- Biochemical engineering. --- afgesloten tijdschriften --- biologie --- exacte wetenschappen --- 577.1 --- Biomedical Engineering. --- Biochemistry. --- 57:62 --- 66.098 --- 57 --- 579 --- Biotechnologies --- Engineering, Biomedical --- Clinical Engineering --- Engineering, Clinical --- Biomedical Technology --- .chemische basis van leven. biochemie en bio-organische chemie in het algemeen --- Biologische wetenschappen in het algemeen. Biologie-:-Ingenieurswetenschappen. Technologie in het algemeen --- Biological processes. Biotechnology --- Biological sciences in general --- Microbiology --- Agricultural Biotechnology --- Agriculture Sciences --- General and Others --- Biochemistry --- Biomedical engineering --- Engineering --- Environmental Sciences --- Health Sciences --- Life Sciences --- Agriculture Sciences. --- Biomedical engineering. --- Engineering. --- Environmental Sciences. --- Health Sciences. --- Life Sciences. --- 579 Microbiology --- 66.098 Biological processes. Biotechnology --- biochemie --- Génie biochimique --- Périodiques --- EBSCOASP-E EJBIOMO EPUB-ALPHA-N EPUB-PER-FT MDBIOCHE MDBIOTEC NPG-E --- Biomedical Engineering --- periodicals. --- Chemical engineering --- Genetic engineering --- Bio-process engineering --- Bioprocess engineering --- moleculaire biologie --- Medicine --- Life sciences --- Agriculture --- Bioinformatics --- Life Sciences, general --- Biomedicine, general --- Biomedical Engineering/Biotechnology --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Farming --- Husbandry --- Industrial arts --- Food supply --- Land use, Rural --- Biosciences --- Sciences, Life --- Science --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Health Workforce --- Data processing --- MDBIOCHE MDBIOTEC --- Biotechnologie. --- bioengineering.