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The ordered growth and functioning of animal cells requires the transfer of information from one part of the cell to another. This information comes from a bewildering variety of sources, both within and outside the cell. Hormones, neurotransmitters, growth factors and extracellular metabolites interact with specific receptors on the plasma membrane or in the cytoplasm. Inside the cell, information is relayed by intracellular messengers, including cyclic nucleotides, inositol polyphosphates, diacylglycerol and calcium, and by GTP-binding proteins, protein kinases, and DNA-binding proteins. Finely balanced interactions between these different signalling pathways ensure that the required response occurs, and abnormalities in any of the components of the system can lead to a variety of diseases, including cancer. This textbook brings together and puts into perspective a large body of knowledge about intracellular signalling systems. Written in a clear and authoritative style, with many illustrations, it will be invaluable to students on advanced undergraduate and graduate courses. It also provides a detailed introduction to and review of this central topic for researchers in cell biology and related disciplines.

Animal biochemistry --- Zoohistology. Zoocytology --- Cell interaction. --- Régulation cellulaire --- Interaction --- Cell interaction --- Régulation cellulaire --- Cellular control mechanisms --- Cellular control mechanisms. --- Cellules --- Cellular signal transduction

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This text describes experimental methods that bridge active and fertile areas of cell biological research. It is focused on methods for understanding dynamic changes in cell structure and their relationship to the regulation of cell behaviour.

Cytoskeleton. --- Cellular control mechanisms. --- Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Cell regulation --- Biological control systems --- Cell metabolism --- Cell skeleton --- Skeleton, Cell --- Cytoplasm --- Histology. Cytology

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This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretes growth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models the interaction between a tumor and the immune system. Chapter 5 is concerned with chemotherapy; it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6 reviews mathematical results for various cancer models.

51-7 --- 51:37 --- 51:37 Mathematics-:-Opvoeding en onderwijs --(algemeen) --- Mathematics-:-Opvoeding en onderwijs --(algemeen) --- 51-7 Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc. --- Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc. --- Neurosciences informatiques --- Differential Equations. --- Mathematical Biology in General. --- Ordinary Differential Equations. --- Computational Mathematics and Numerical Analysis. --- Computer Appl. in Life Sciences. --- Models, Neurological --- Nerve Net --- Mathematical Modeling and Industrial Mathematics. --- Muscle Contraction --- Musculoskeletal Physiological Processes --- Musculoskeletal Physiological Phenomena --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Computer mathematics --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Musculoskeletal Physiologic Process --- Musculoskeletal Physiological Concepts --- Musculoskeletal Physiological Phenomenon --- Physiology, Musculoskeletal --- Musculoskeletal Physiologic Processes --- Musculoskeletal Physiological Process --- Musculoskeletal Physiology --- Concept, Musculoskeletal Physiological --- Concepts, Musculoskeletal Physiological --- Musculoskeletal Physiological Concept --- Phenomena, Musculoskeletal Physiological --- Phenomenon, Musculoskeletal Physiological --- Physiologic Process, Musculoskeletal --- Physiologic Processes, Musculoskeletal --- Process, Musculoskeletal Physiologic --- Process, Musculoskeletal Physiological --- Processes, Musculoskeletal Physiologic --- Processes, Musculoskeletal Physiological --- Active Ion Transport --- Facilitated Ion Transport --- Passive Ion Transport --- Antiport --- Ion Cotransport --- Ion Exchange, Intracellular --- Symport --- Uniport --- Cotransport, Ion --- Exchange, Intracellular Ion --- Intracellular Ion Exchange --- Ion Transport, Active --- Ion Transport, Facilitated --- Ion Transport, Passive --- Transport, Active Ion --- Transport, Ion --- Second Messengers --- Intracellular Second Messengers --- Intracellular Second Messenger --- Messenger, Second --- Messengers, Intracellular Second --- Messengers, Second --- Second Messenger --- Second Messenger System --- Second Messenger, Intracellular --- Second Messengers, Intracellular --- System, Second Messenger --- Systems, Second Messenger --- Calcium Puffs --- Calcium Sparks --- Calcium Spikes --- Calcium Oscillations --- Calcium Waves --- Calcium Oscillation --- Calcium Puff --- Calcium Signalings --- Calcium Spark --- Calcium Spike --- Calcium Wave --- Oscillation, Calcium --- Oscillations, Calcium --- Puff, Calcium --- Puffs, Calcium --- Signaling, Calcium --- Signalings, Calcium --- Spark, Calcium --- Sparks, Calcium --- Spike, Calcium --- Spikes, Calcium --- Wave, Calcium --- Waves, Calcium --- Muscular Contraction --- Inotropism --- Contraction, Muscle --- Contraction, Muscular --- Contractions, Muscle --- Contractions, Muscular --- Inotropisms --- Muscle Contractions --- Muscular Contractions --- Calculus of Variations and Optimal Control; Optimization. --- Physiological, Cellular and Medical Topics. --- Cell Cycle --- Processes, Cell Growth --- Cell Division Cycle --- Cell Cycles --- Cell Division Cycles --- Cycle, Cell --- Cycle, Cell Division --- Cycles, Cell --- Cycles, Cell Division --- Division Cycle, Cell --- Division Cycles, Cell --- Cell Multiplication --- Cell Number Growth --- Cell Growth in Number --- Cellular Proliferation --- Growth, Cell Number --- Multiplication, Cell --- Number Growth, Cell --- Proliferation, Cell --- Proliferation, Cellular --- Mathematics. --- Cell biology. --- Mathematical models. --- Biomathematics. --- Mathematical and Computational Biology. --- Cell Biology. --- Differential equations. --- Partial differential equations. --- Calculus of variations. --- Partial Differential Equations. --- Bioinformatics. --- Computational biology. --- Neurobiology. --- Computer mathematics. --- Ecology --- Evolution (Biology) --- Phylogeny --- Population genetics --- Animal phylogeny --- Animals --- Phylogenetics --- Phylogeny (Zoology) --- Biology --- Mathematical models --- Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc --- Math --- Science --- Mathematics --- Models, Mathematical --- Simulation methods --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Neurosciences --- Discrete mathematics --- Electronic data processing --- Partial differential equations --- 517.91 Differential equations --- Differential equations --- Bioinformatics --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Data processing --- Isoperimetrical problems --- Variations, Calculus of --- Maxima and minima --- Cellular signal transduction. --- Calcium --- Physiological effect. --- Computational neuroscience. --- Differential equations, partial. --- Mathematical optimization. --- Physiology --- Computer science --- Data processing. --- Cytology. --- Animal physiology --- Anatomy --- Optimization (Mathematics) --- Optimization techniques --- Optimization theory --- Systems optimization --- Mathematical analysis --- Operations research --- System analysis --- Cell proliferation. --- Cell cycle. --- Cancer cells. --- Pathology, Cellular --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Cell renewal --- Cellular proliferation --- Cell cycle --- Cell division --- Cell populations --- Growth --- Neural circuitry --- Auditory pathways. --- Cellular signal transduction --- Physiological transport --- Physiological effect --- Metabolism --- Bioinformatics . --- Computational biology . --- Calcium - Physiological effect.