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book (3)


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English (3)


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2022 (3)

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Book
Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations
Authors: --- ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This e-book summarises the latest advances in the rheumatic diseases with a focus on the recent efforts of vascular and pulmonary manifestations and anticipate the new and future directions of these research topic. Rheumatic diseases represent a heterogeneous group of severe autoimmune disorders. The present Special Issue aims to provide an overview of the complexity of vascular and pulmonary manifestations of rheumatologic diseases and helps in knowledge to manage them. The eleven published articles here collected underline the complexity of rheumatic diseases and the difficult to treated them. The manuscripts provide an overview of the pathophysiology and current treatment regimes of these disorders, highlighting tools which assist with diagnosis, risk stratification and therapy. Finally, we underline the importance of a multidisciplinary team working using the skills of clinicians, radiologists, and pathologists.


Book
Embryo Implantation and Placental Development
Author:
ISBN: 3036558535 3036558543 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book aims to provide novel insights into the mechanisms of embryo implantation and placental development, as well as at present an overview of the current knowledge on the different signaling pathways regulating the early steps of implantation and placentation, and on the pathological alterations which may impair the establishment of a physiological pregnancy.

Keywords

Research & information: general --- Biology, life sciences --- fetuin-A --- GDM --- cell growth --- centrosome --- primary cilium --- autophagy --- implantation --- endometrium --- blastocyst --- embryo --- chorionic gonadotropin --- progesterone --- Notch --- cytokines --- placenta --- amino acid transporter --- mammalian target of rapamycin --- gestational diabetes --- trophectoderm --- cell proliferation --- let-7 miRNAs --- gene regulation --- fractalkine --- trophoblast --- bilaminar co-culture --- miRNA --- trophoblast cells --- ARID3B complex --- decidualization --- adverse pregnancy outcome --- preconception --- preimplantation genetic screening --- in-vitro fertilization --- biopsy --- euploid embryo --- pregnancy --- mosaicism --- development --- flow culture --- KIT receptor --- KITD816V --- placental development --- premature differentiation --- trophoblast stem cell --- trophoblast giant cell --- spongiotrophoblast --- invasion --- embryonic growth retardation --- Jag1 --- Dll4 --- endothelial cells --- decidua --- angiogenesis --- capillaries --- spiral arteries --- Stabilin-1 --- Stabilin-2 --- double knockout --- hemorrhage --- RNA-seq --- ChIP-seq --- enhancers --- transcription factors --- PLAGL1 --- tube formation --- blood vessel development --- PlGF --- Flt-1/VEGFR1 --- immune modulation --- human placenta --- lopinavir --- mitochondria --- Mfn2 --- UPR --- IRE1α --- placental dysfunction --- assisted reproduction techniques --- infertility --- preeclampsia --- intrauterine growth restriction --- trophoblast invasion --- sFLT-1 --- EGFL7 --- placenta-derived mesenchymal stromal cells --- mouse model


Book
Recent Clinical Research on Glaucoma
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In the past few years, knowledge about glaucoma diagnosis and follow up has evolved dramatically through advances in intraocular pressure (IOP) measurement, corneal biomechanics, structural and functional assessment of the ocular surface, anterior chamber, retina, optic nerve and intracranial visual pathways, as well as the advent of artificial intelligence. In addition, the development of new modalities of IOP-lowering and non-IOP-lowering drugs, alternative deliveries, refined laser technologies, and minimally invasive glaucoma surgery (MIGS) techniques with different implants have widened the therapeutic possibilities for treating this disease. Finally, current insights into risk factors and quality of life in relation to glaucomatous impairment are emerging. The purpose of this Special Issue is to present the latest exciting clinical developments that are taking place in the field of glaucoma.

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