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Electronic cigarettes (E-cigarettes), also known as vape devices or by trade names such as JUUL, are handheld devices that aerosolize liquid commonly containing nicotine, humectants and flavorings. Used by 1 in 5 high school students in 2020, they are the most common tobacco product used by youth. E-cigarette use has been associated with a variety of health issues such as nicotine addiction, e-cigarette or vaping associated lung illness (EVALI), seizures, and increased risk of cardiovascular disease. This first-of-its-kind book begins with an introduction and background on the historical context of tobacco products. The next chapters provide an overview of the e-cigarette landscape and reviews the e-cigarette devices and solutions and the evolution of these products. This is followed by reviews of the health effects of e-cigarettes on users and non-users and includes recommendations for prevention and treatment of youth e-cigarette use. The last few chapters address the public health impact of e-cigarettes with a review of the evidence of e-cigarettes in smoking cessation. The book closes with policy and advocacy approaches and a resource page. E-cigarette and vape device use pose a public health crisis. This book contains succinct practical information and is a key reference for pediatricians as well as clinicians of all specialities. It also serves as a resource for health professionals, including tobacco dependence treatment providers and public health experts.

Pediatrics. --- Respiratory organs—Diseases. --- Pneumology/Respiratory System. --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Diseases --- Health and hygiene --- Electronic cigarettes. --- Teenagers --- Electronic Nicotine Delivery Systems. --- Vaping. --- Adolescent. --- Child. --- Tobacco use. --- E-Cigarettes --- E-Cigs --- E-Cig --- E-Cigarette --- Electronic Cigarette --- Electronic Cigarettes --- Electronic Nicotine Delivery System --- Cigarette, Electronic --- Cigarettes, Electronic --- E Cig --- E Cigarette --- E Cigarettes --- E Cigs --- Adolescents --- Teen-agers --- Teens --- Young adults (Teenagers) --- Youth --- E-cigarettes --- Electronic nicotine delivery systems --- Cigarettes --- E-Cig Use --- E-Cigarette Use --- Electronic Cigarette Use --- Vape --- ECig Use --- Ecigarette Use --- Nicotine Vaping --- THC Vaping --- Cigarette Use, Electronic --- E Cig Use --- E Cigarette Use --- E-Cig Uses --- E-Cigarette Uses --- ECig Uses --- Ecigarette Uses --- Electronic Cigarette Uses --- Nicotine Vapings --- THC Vapings --- Use, E-Cig --- Use, E-Cigarette --- Use, ECig --- Use, Ecigarette --- Use, Electronic Cigarette --- Uses, Ecigarette --- Vapes --- Vaping, Nicotine --- Vaping, THC --- Vapings, Nicotine --- Vapings, THC --- E-Cigarette Vapor --- Minors --- Adolescents, Female --- Adolescents, Male --- Adolescence --- Adolescent, Female --- Adolescent, Male --- Female Adolescent --- Female Adolescents --- Male Adolescent --- Male Adolescents --- Teen --- Teenager --- Youths --- Electronic cigarettes --- Health aspects. --- Cigarretes electròniques --- Pipes per a tabac --- Fumadors --- Hàbit de fumar --- Addicció al tabac --- Consum de tabac --- Tabaquisme --- Abús de substàncies --- Conducta compulsiva --- Hàbit --- Cigarretes --- Hàbit de fumar en l'embaràs --- Tabac --- Persones --- Joves --- Adolescents maltractats --- Noies adolescents --- Nois adolescents --- Migrants adolescents --- Infants --- Psicoteràpia dels adolescents --- Psiquiatria de l'adolescència --- Cigarreta electrònica --- E-cigarretes

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In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.

Research & information: general --- Chemistry --- Analytical chemistry --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC-MS --- LC-HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC-MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations --- on!® nicotine pouches --- nicotine --- dissolution --- release profile --- validation --- product assessment --- smokeless tobacco product --- nicotine degradants --- nicotine-related impurities --- alkaloids --- nicotine degradation products --- nicotine pouches --- reduced-risk products --- constituents --- method development --- method validation --- JUUL --- aerosol --- non-targeted analysis --- chemical characterization --- ENDS --- e-cigarette --- GC-MS --- LC-HRMS --- e-liquid --- 2,4-DNPH derivatization --- formaldehyde --- --- formaldehyde-containing hemiacetal/acetal adducts --- HPHC --- GC-MS --- 3-hydroxybenzo[a]pyrene --- LC-MS/MS --- urine --- human biomonitoring --- derivatization --- potentially reduced-risk products --- propylene glycol --- electronic cigarette --- biomarker of exposure --- compliance marker --- oral tobacco derived nicotine (OTDN) pouches --- snus --- nicotine release --- nicotine dissolution --- nicotine extraction --- equivalence --- modern oral nicotine products --- HPHCs --- product characterizations