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Microorganisms --- Disinfection and disinfectants --- Micro-organismes --- Physiology --- Physiologie --- Disinfection and disinfectants. --- Antiviral Agents. --- Bacteria --- Drug Resistance, Microbial. --- Fungi --- Physiology. --- drug effects --- -579 --- 57.083 --- 579.26 --- 579.61 --- 615.28 --- 614.48 --- 632.953.1 --- --- Germs --- Micro-organisms --- Microbes --- Microscopic organisms --- Organisms --- Microbiology --- Disinfectants --- Germicides --- Sanitation --- Fumigation --- Antiviral Drugs --- Antivirals --- Agents, Antiviral --- Drugs, Antiviral --- Interferon Inducers --- Virus Diseases --- Viruses --- Virus Inactivation --- Antimicrobial Drug Resistance --- Antibiotic Resistance --- Antibiotic Resistance, Microbial --- Antimicrobial Drug Resistances --- Drug Resistances, Microbial --- Resistance, Antibiotic --- Microbial Sensitivity Tests --- drug effects. --- Antiviral Agents --- Drug Resistance, Microbial --- 579 --- Microbial physiology --- Antiviral --- Antiviral Agent --- Antiviral Drug --- Agent, Antiviral --- Drug, Antiviral

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Virus inhibitors --- Virus diseases --- Antiviral agents --- Virus Inhibitors --- Virus Diseases --- Antiviral Agents --- immunology --- Antiviral Agents. --- Virus research --- Agents antiviraux --- Antiviraux --- Maladies à virus --- Virus --- Antiviral agents. --- Virus diseases. --- Virus inhibitors. --- immunology. --- Périodiques. --- Inhibiteurs --- Immunologie --- Antiviruses --- Viral diseases --- Viral infections --- Virus infections --- Antiviral drugs --- Antivirals --- Antiviral Drugs --- Agents, Antiviral --- Drugs, Antiviral --- Viruses --- Communicable diseases --- Medical virology --- Pathogenic viruses --- Anti-infective agents --- Interferon Inducers --- Virus Inactivation --- Chemotherapy --- Antiviral --- Antiviral Agent --- Antiviral Drug --- Agent, Antiviral --- Drug, Antiviral --- Virus Diseases. --- Viral Diseases --- Viral Infections --- Virus Infections --- Disease, Viral --- Disease, Virus --- Diseases, Viral --- Diseases, Virus --- Infection, Viral --- Infection, Virus --- Infections, Viral --- Infections, Virus --- Viral Disease --- Viral Infection --- Virus Disease --- Virus Infection --- Antiviraux. --- Periodicals. --- Viral Protease Inhibitors. --- Inhibitor of Viral Protease --- Virus Protease Inhibitors --- Inhibitors, Viral Protease --- Inhibitors, Virus Protease --- Protease Inhibitor, Viral --- Protease Inhibitors, Viral --- Protease Inhibitors, Virus --- Viral Protease Inhibitor --- Viral Proteases --- antagonists & inhibitors --- Viral Inactivation --- Inactivation, Viral --- Inactivation, Virus --- Maladies à virus --- Périodiques.

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Antiviral agents are used for the treatment of viral diseases. Antiviral drugs have been successfully developed and used clinically for a limited number of important human viral diseases notably caused by human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), herpes, and influenza viruses. Despite the successes of these antiviral drugs, issues with drug resistance and toxicity remain challenging. These challenges are driving research to identify new drug candidates and to investigate novel drug targets to develop new mechanistic drug classes. Antiviral agents are not available against many viruses that cause human disease and economic burdens; in particular, the development of antiviral agents against emerging, re-emerging, and neglected viruses is increasingly becoming a priority. This book includes six review articles that discuss new antiviral strategies. The reviews either discuss advances relating to a specific virus or new therapeutic targets and approaches. The book includes 15 original research articles reporting new antiviral agents against a variety of clinically and economically important viruses and studies into the prevalence or acquisition of drug resistance. Overall, this book is an exciting collection of new research and ideas relating to the development of antiviral agents.

Research & information: general --- Biology, life sciences --- Zika virus --- nucleoside analogues --- antiviral agents --- NS5 --- prodrugs --- ProTides --- neural stem cells --- RNA-dependent RNA polymerase --- cytomegalovirus --- latent infection --- TALEN --- Surveyor nuclease mutation detection assay --- ie-1 gene --- quantitative real-time PCR --- Epstein-Barr virus --- herpes viruses --- lytic gene expression --- Burkitt lymphoma cells --- clozapine --- antipsychotic drug --- antiviral drug --- enteroviruses --- coxsackievirus B4 --- persistent infection --- fluoxetine --- resistance --- mutations --- herpes B virus --- macacine herpesvirus-1 --- genistein --- flavonoids --- acyclovir --- ganciclovir --- Plantago asiatica --- Clerodendrum trichotomum --- RSV --- therapeutic effects --- acteoside --- human antimicrobial peptides --- antiviral strategies --- defensins --- cathelicidins --- hepcidins --- transferrins --- influenza A virus --- brevilin A --- antiviral --- sesquiterpene lactone --- replication --- PRRSV --- polyethylenimine --- PEI --- virion internalization --- endocytosis --- HIV --- pediatrics --- Ethiopia --- pre-treatment drug resistance --- combination antiretroviral therapy (cART) --- dried plasma spots --- dried blood spots --- sphingolipids --- glycosphingolipids --- viruses --- lipid biosynthesis --- flavivirus --- Japanese encephalitis virus --- furin inhibitor --- precursor membrane protein --- measles virus --- central nervous system --- tropism --- treatments --- porcine reproductive and respiratory syndrome virus --- ginsenoside Rg1 --- antiviral activity --- pro-inflammatory factor --- NF-κB signaling pathway --- acute/latent infection --- congenital infection --- antiviral agent --- therapeutic strategies --- nucleic acid-based therapeutic approach --- HCMV vaccine --- adoptive cell therapy --- Rev response element --- chemical footprinting --- SHAPE --- drug discovery --- branched peptides --- herpesvirus --- immediate-early --- IE1 --- IE2 --- ribozyme --- RNA interference --- CRISPR/Cas --- small molecule --- orthohantavirus --- phenyl-benzotriazoles --- C-FRA --- Porcine circovirus type 2 --- epigallocatechin gallate --- heparan sulfate --- antiviral effect --- virus attachment --- microvirin --- lectin --- human immunodeficiency virus --- hepatitis C virus --- antiviral inhibitor --- non-immunogenic --- viral entry --- protein drugs --- LUMS1 --- oleanane-type derivatives --- influenza A virus (IAV) --- virus entry inhibitors --- hemagglutinin (HA)