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Ulcerative colitis (UC) is one of the major forms of inflammatory bowel disease (IBD). Epidemiological trends suggest an initial rise in the incidence of UC, followed by Crohn's disease (CD), in areas where IBD is emerging. As understanding of aspects of the disease is evolving, this book covers new perspectives on the etiology, clinical manifestations, diagnosis, and management of UC. Genetic predisposition, along with gut dysbiosis and environmental factors, triggers the altered gut permeability and dysregulated immune activation that leads to the development of UC, which can manifest both intestinally and extra-intestinally. Platelets play a significant role in augmenting inflammation. Histological examination is important for accurate diagnosis and for distinguishing mimics. Histological remission is an emerging treatment target strategy in UC. Novel treatments include dietary manipulation with anti-inflammatory dietary components like fermented rice bran. A number of challenges need to be addressed in treating special populations like children and pregnant women. Finally, interventional endoscopy is playing an emerging role in the management of colitis-associated neoplasia and postoperative complications and acting as a bridge between surgery and medical therapy. Ulcerative Colitis - Etiology, Diagnosis, Diet, Special Populations, and the Role of Interventional Endoscopy aims to act as a ready reference for the clinician. It provides indispensable updates on several relevant issues in the diagnosis and management of ulcerative colitis and has benefited from the collaboration of leading experts in various aspects of the disease. It aims to facilitate decision-making by gastroenterologists, IBD specialists, interventional endoscopists, dieticians, pathologists, surgeons, and pediatricians treating UC patients.

Ulcerative colitis.

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This book is intended to act as an up-to-date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular, Ulcerative Colitis. All authors of the chapters are experts in their fields of publication, and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating, and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine.

Ulcerative colitis. --- Colitis --- Inflammatory bowel diseases --- Hepatology

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Ulcerative colitis (UC) is one of the major forms of inflammatory bowel disease (IBD). Epidemiological trends suggest an initial rise in the incidence of UC, followed by Crohn's disease (CD), in areas where IBD is emerging. As understanding of aspects of the disease is evolving, this book covers new perspectives on the etiology, clinical manifestations, diagnosis, and management of UC. Genetic predisposition, along with gut dysbiosis and environmental factors, triggers the altered gut permeability and dysregulated immune activation that leads to the development of UC, which can manifest both intestinally and extra-intestinally. Platelets play a significant role in augmenting inflammation. Histological examination is important for accurate diagnosis and for distinguishing mimics. Histological remission is an emerging treatment target strategy in UC. Novel treatments include dietary manipulation with anti-inflammatory dietary components like fermented rice bran. A number of challenges need to be addressed in treating special populations like children and pregnant women. Finally, interventional endoscopy is playing an emerging role in the management of colitis-associated neoplasia and postoperative complications and acting as a bridge between surgery and medical therapy. Ulcerative Colitis - Etiology, Diagnosis, Diet, Special Populations, and the Role of Interventional Endoscopy aims to act as a ready reference for the clinician. It provides indispensable updates on several relevant issues in the diagnosis and management of ulcerative colitis and has benefited from the collaboration of leading experts in various aspects of the disease. It aims to facilitate decision-making by gastroenterologists, IBD specialists, interventional endoscopists, dieticians, pathologists, surgeons, and pediatricians treating UC patients.

Ulcerative colitis. --- Colitis --- Inflammatory bowel diseases

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Immunology --- microbiome --- gut microbiota --- mucosal immunology --- intestinal immunity --- intestinal homeostasis --- inflammatory bowel diseases --- Crohn's diseases --- ulcerative colitis --- microbiome --- gut microbiota --- mucosal immunology --- intestinal immunity --- intestinal homeostasis --- inflammatory bowel diseases --- Crohn's diseases --- ulcerative colitis

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The conditions of Crohn’s disease and ulcerative colitis are excellent examples of  how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies are sometimes complex and associated with important risks requiring a deeper understanding of their molecular principles from clinicians.   Crohn’s Disease and Ulcerative Colitis serves as a unique combined resource for physicians and scientists addressing the needs of both groups. It will stimulate exchange and collaboration and shorten the path between discovery and application of new knowledge and also help clinicians understand new therapeutic concepts from their origins. This volume provides an introduction to mucosal immunology which forms the basis of modern immunotherapy. It also serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy as well as conventional and complex immunomodulatory principles. Each chapter is written by experts in their field and includes the most up to date information. Crohn’s Disease and Ulcerative Colitis will be of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis and related autoimmune disorders.

Colitis, Ulcerative -- Popular Works. --- Crohn Disease -- Popular Works. --- Crohn's disease -- Popular works. --- Ulcerative colitis -- Popular works. --- Crohn's disease --- Colitis --- Inflammatory Bowel Diseases --- Gastroenteritis --- Colonic Diseases --- Intestinal Diseases --- Gastrointestinal Diseases --- Digestive System Diseases --- Diseases --- Crohn Disease --- Colitis, Ulcerative --- Medicine --- Health & Biological Sciences --- Gastroenterology --- Ulcerative colitis --- Immunology. --- Epidemiology. --- Diagnosis. --- Treatment. --- Immunobiology --- Colitis, Granulomatous --- Crohn disease --- Enteritis, Regional --- Granulomatous colitis --- Granulomatous enteritis --- Ileitis, Regional --- Ileocolitis --- Regional enteritis --- Regional ileitis --- Terminal enteritis --- Medicine. --- Gastroenterology. --- Medicine & Public Health. --- Inflammatory bowel diseases --- Life sciences --- Serology --- Internal medicine --- Digestive organs --- Gastroenterology .