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Dissertation
Immunisation contre la somatostatine chez les bovins : répercussions zootechniques et hormonales.
Author:
Year: 1986

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Keywords

Immunization --- Somatostatin --- Cattle

Somatostatin and its receptors.
ISBN: 0471953822 Year: 1995 Publisher: New York, NY ; Chichester : John Wiley,

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Dissertation
Examen de l'évolution de certains composants sanguins chez le bovin en croissance immunisé contre la somatostatine.
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Year: 1987

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Book
The gut as an endocrine organ
Authors: ---
Year: 1994 Publisher: London : Baillière-Tindall,


Book
Peptides in oncilogy II : somatostatin analogues and bombesin antagonists
Author:
ISBN: 3540566694 0387566694 364284958X 3642849563 Year: 1993 Volume: vol 129 Publisher: Berlin : Springer-Verlag,

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Dissertation
Somatostatin immunoneutralization in the chicken : immunogen development and effect on growth.
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Year: 1994 Publisher: Leuven : KUL, Fakulteit Landbouwkundige en Toegepaste Biologische Wetenschappen,

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Somatostatin
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ISBN: 1402080336 1402077998 Year: 2004 Publisher: New York, NY : Springer US : Imprint: Springer,

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Abstract

Thirty years have passed since somatostatin was discovered and its hormonal function defined [1,2]. The wide range of anatomical distribution and actions of somatostatin and its receptors stimulated intense scientific and clinical interest, and fostered extensive research into all aspects of its biology including regulation of its gene expression, processing of its precursor, biological and cellular actions relating to regulation cell secretion, motility and proliferation. The development of metabolically stable peptide analogs helped define its usefulness in the treatment of endocrine diseases and cancer. The heterogeneity of somatostatin receptors recognized in 1981 [3] was later shown to result from the existence and variable expression of five distinct subtypes that constitutes two distinct subfamilies with distinguishing pharmacological characteristics [4,5]. The molecular cloning of these receptor subtypes reignited the interest in this field leading to a major increase in our insight into the biology of somatostatin and its receptor subtypes, and has led to the design and development of subtype-selective peptide and non-peptide agonists and antagonists. Significant progress has been made in both basic and clinical research on somatostatin. Noteworthy developments include the role of somatostatin in neuronal patterning, delineation of subtype-selective cytostatic / cytotoxic antiproliferative actions, manipulation of cellular signaling by oligomeric association of somatostatin receptor subtypes amongst themselves or with other G protein-coupled receptors, application of radionuclide-tagged derivatives to localize somatostatin receptor positive tumors and their treatment through targeted delivery of radionuclide or chemotoxin tagged agonists through receptor-mediated endocytosis.


Book
Biomarkers in Neurodegenerative Diseases
Author:
ISBN: 303655730X 3036557296 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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This book focuses on the recent advancements in both fundamental and clinical research, focusing on identifying, developing, and applying new and improved biological markers for specific neurologic disorders in the future. The original research work and review articles published here highlight some unique mechanisms underlying the most prevalent pathophysiological conditions affecting human health. Other areas covered in the book include emerging treatment options and correct diagnoses using different biochemical and imaging techniques.

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