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Immunization --- Somatostatin --- Cattle
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SOMATOSTATIN --- RECEPTORS, SOMATOSTATIN --- RECEPTORS --- PHYSIOLOGY --- PHYSIOLOGY --- SOMATOSTATIN --- RECEPTORS, SOMATOSTATIN --- RECEPTORS --- PHYSIOLOGY --- CONGRESSES --- PHYSIOLOGY
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Cattle --- Somatostatin --- Immunization --- Immune response --- Composant sanguin --- Composant sanguin
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GASTROINTESTINAL SYSTEM --- GASTROINTESTINAL HORMONES --- NEUROREGULATORS --- GASTROINTESTINAL NEOPLASMS --- SOMATOSTATIN --- PHYSIOLOGY --- GASTROINTESTINAL SYSTEM --- GASTROINTESTINAL HORMONES --- NEUROREGULATORS --- GASTROINTESTINAL NEOPLASMS --- SOMATOSTATIN --- PHYSIOLOGY
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Cancer --- Hormone therapy --- Somatostatin --- Agonists --- Therapeutic use --- Bombesin --- Antagonists --- SOMATOSTATIN --- BOMBESIN --- NEOPLASMS --- ANALOGS & DERIVATIVES --- PHARMACOLOGY --- ANTAGONISTS AND INHIBITORS --- DRUG THERAPY --- DIAGNOSIS
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Somatostatin --- Somatostatin --- chickens --- chickens --- Immunogenetics --- Immunogenetics --- Immunization --- Immunization --- Immune response --- Immune response --- animal growth promoters --- animal growth promoters --- Broiler chickens --- Broiler chickens
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Thirty years have passed since somatostatin was discovered and its hormonal function defined [1,2]. The wide range of anatomical distribution and actions of somatostatin and its receptors stimulated intense scientific and clinical interest, and fostered extensive research into all aspects of its biology including regulation of its gene expression, processing of its precursor, biological and cellular actions relating to regulation cell secretion, motility and proliferation. The development of metabolically stable peptide analogs helped define its usefulness in the treatment of endocrine diseases and cancer. The heterogeneity of somatostatin receptors recognized in 1981 [3] was later shown to result from the existence and variable expression of five distinct subtypes that constitutes two distinct subfamilies with distinguishing pharmacological characteristics [4,5]. The molecular cloning of these receptor subtypes reignited the interest in this field leading to a major increase in our insight into the biology of somatostatin and its receptor subtypes, and has led to the design and development of subtype-selective peptide and non-peptide agonists and antagonists. Significant progress has been made in both basic and clinical research on somatostatin. Noteworthy developments include the role of somatostatin in neuronal patterning, delineation of subtype-selective cytostatic / cytotoxic antiproliferative actions, manipulation of cellular signaling by oligomeric association of somatostatin receptor subtypes amongst themselves or with other G protein-coupled receptors, application of radionuclide-tagged derivatives to localize somatostatin receptor positive tumors and their treatment through targeted delivery of radionuclide or chemotoxin tagged agonists through receptor-mediated endocytosis.
Somatostatin. --- Toxicology. --- Oncology . --- Pharmacology/Toxicology. --- Oncology. --- Pharmacology. --- Tumors --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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CALCIBONIN --- CATECHOLAMINES --- TSH --- VITAMINE D --- CHORIONIC GONADOTROPHIN --- DOPAMINE --- GASTRIC INHIBITORY PEPTIDE --- HORMONES GASTRO-INTESTINAL --- IMMUNOASSAY --- MOTILIN --- NORADRENALINE --- PANCRATIC POLYPEPTIDE --- SEROTONIN --- ERYTHROPOIETIN --- GLUCAGON --- GONADOTROPHINS --- GROWTH HORMONE --- INSULIN --- IODINE --- LACTOGENIC HORMONE --- LIQUID CHROMATOGRAPHY --- LIPOTROPHIN --- PROLACTIN --- PROSTAGLANDINS --- SOMATOMEDINS --- SOMATOSTATIN --- THYROTROPIN --- CALCIBONIN --- CATECHOLAMINES --- TSH --- VITAMINE D --- CHORIONIC GONADOTROPHIN --- DOPAMINE --- GASTRIC INHIBITORY PEPTIDE --- HORMONES GASTRO-INTESTINAL --- IMMUNOASSAY --- MOTILIN --- NORADRENALINE --- PANCRATIC POLYPEPTIDE --- SEROTONIN --- ERYTHROPOIETIN --- GLUCAGON --- GONADOTROPHINS --- GROWTH HORMONE --- INSULIN --- IODINE --- LACTOGENIC HORMONE --- LIQUID CHROMATOGRAPHY --- LIPOTROPHIN --- PROLACTIN --- PROSTAGLANDINS --- SOMATOMEDINS --- SOMATOSTATIN --- THYROTROPIN
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HPLC --- ADRENALINE --- ADRENOCORTICOTROPHIN AND LIPOTROPHIN --- ALDOSTERONE --- ANDROGENS --- CORTICOSTEROIDS --- ENDOCRINOLOGY --- GAS CHROMATOGRAPHY --- MASS SPECTROMETRY --- NON ISOTOPIC IMMUNOASSAY --- ESTROGENS --- PROGESTERONE --- RENIN-ANGIOTENSIN SYSTEM --- ERYTHROPOIETIN --- GLUCAGON --- GONADOTROPHINS --- GROWTH HORMONE --- INSULIN --- IODINE --- LACTOGENIC HORMONE --- LIQUID CHROMATOGRAPHY --- LIPOTROPHIN --- PROLACTIN --- PROSTAGLANDINS --- SOMATOMEDINS --- SOMATOSTATIN --- THYROTROPIN --- HPLC --- ADRENALINE --- ADRENOCORTICOTROPHIN AND LIPOTROPHIN --- ALDOSTERONE --- ANDROGENS --- CORTICOSTEROIDS --- ENDOCRINOLOGY --- GAS CHROMATOGRAPHY --- MASS SPECTROMETRY --- NON ISOTOPIC IMMUNOASSAY --- ESTROGENS --- PROGESTERONE --- RENIN-ANGIOTENSIN SYSTEM --- ERYTHROPOIETIN --- GLUCAGON --- GONADOTROPHINS --- GROWTH HORMONE --- INSULIN --- IODINE --- LACTOGENIC HORMONE --- LIQUID CHROMATOGRAPHY --- LIPOTROPHIN --- PROLACTIN --- PROSTAGLANDINS --- SOMATOMEDINS --- SOMATOSTATIN --- THYROTROPIN
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This book focuses on the recent advancements in both fundamental and clinical research, focusing on identifying, developing, and applying new and improved biological markers for specific neurologic disorders in the future. The original research work and review articles published here highlight some unique mechanisms underlying the most prevalent pathophysiological conditions affecting human health. Other areas covered in the book include emerging treatment options and correct diagnoses using different biochemical and imaging techniques.
Medicine --- Alzheimer’s disease --- amyloid beta --- hippocampus --- Kir channels --- K+ channels --- glioblastoma multiforme --- low-grade glioma --- astrocytoma --- recurrence --- multifocal growth --- mRNA expression --- MPS1 --- TTK --- therapy --- EDTA chelation therapy --- neurodegenerative diseases --- metal detoxification --- reactive oxygen species (ROS) --- neuroinflammation --- neurodegeneration --- cognitive dysfunction --- neurofibrillary tangles --- diagnosis methods --- biomarkers --- perinatal stress --- NURR1 --- inflammation --- late-onset diseases --- early life --- artificial neural network --- deep learning --- Parkinson’s disease --- atypical parkinsonian syndrome --- dopamine transporter SPECT --- β-Amyloid --- calpain --- Collapsin Response Mediator Protein-2 --- human-neuroblastoma SH-SY5Y cells --- Somatostatin-14 --- somatostatin receptor --- brain injury --- quinpirole --- dopamine D2 receptors --- glial cell --- autophagy --- mitophagy --- multiple sclerosis --- biomarker --- neurons --- astrocytes --- Alzheimer’s and Parkinson’s diseases --- fluid and imaging biomarkers --- amyloid-β and tau --- miRNA --- extracellular vesicles --- exosomes and ectosomes --- PET --- radiotracers --- radiolabeled molecules --- n/a --- Alzheimer's disease --- Parkinson's disease --- Alzheimer's and Parkinson's diseases
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