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Book
Laser Speckle Contrast Imaging in Reconstructive Surgery.
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ISBN: 9179298729 Year: 2020 Publisher: Linköping : Linkopings Universitet,

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Abstract

This dissertation by Johan Zötterman explores the use of Laser Speckle Contrast Imaging (LSCI) in reconstructive surgery. It investigates the technology's application for non-invasive tissue perfusion monitoring, comparing it to other methods like Laser Doppler Flowmetry (LDF). Through various studies, the research evaluates LSCI's effectiveness in detecting venous outflow obstruction and predicting flap necrosis in surgical procedures. The work highlights LSCI's advantages, such as fast acquisition time and spatial resolution, while acknowledging limitations like sensitivity to motion artifacts and inability to provide absolute perfusion data. The dissertation is intended for medical professionals and researchers interested in advanced imaging techniques for surgical applications.


Book
Blood Flow Dynamics in Burns
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ISBN: 9789179299453 Year: 2019 Publisher: Linkopings Universitet

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This dissertation explores the use of laser speckle contrast imaging (LSCI) to evaluate the healing potential of burns with intermediate thickness. The primary focus is on comparing LSCI to the more established laser Doppler imaging (LDI) method, highlighting LSCI's advantages in terms of ease of use and accuracy. The research aims to identify the optimal time for perfusion measurement and assess the accuracy of different cut-offs in predicting surgical needs. The study, involving 77 patients, demonstrates that LSCI can predict surgical requirements with high sensitivity and specificity within hours of injury. The dissertation emphasizes the importance of early diagnosis and intervention to improve healing outcomes and reduce patient suffering. It targets medical professionals and researchers in the field of burn treatment and imaging technology.


Book
Quantitative perfusion MRI : techniques, applications and practical considerations
Authors: ---
ISBN: 0323952097 0323952100 9780323952101 9780323952095 Year: 2023 Publisher: Cambridge, MA : Elsevier Inc.,


Book
Diagnosis, Prevention and Treatment for Stroke
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Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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In recent years, there have been outstanding achievements in stroke diagnosis and care. Our better understanding of the pathophysiological mechanisms and the advances in neuro-imaging have enabled us to diagnose stroke syndromes with remarkable precision and uncover underlying vessel pathologies that can be directly correlated to the stroke event. Within a short period of time, mechanical thrombectomy became the standard of care for patients with large vessel occlusions and symptom onset up to 24 hours, while other recent trials also suggest the use of perfusion imaging to guide intravenous thrombolysis in the extended time window. In this Special Issue, we will also extensively discuss relevant topics on secondary stroke prevention, including the prompt use of nonvitamin k oral anticoagulants and the potential effect of reversal agents in patients with intracerebral hemorrhage related to their use. We will also delineate treatment options for stroke patients with indication for long-term anticoagulation and high bleeding risk. Finally, a particular mention will be made for young patients with stroke, the extent of the diagnostic work-up, and the selection of those who would benefit from patent foramen ovale closure.

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