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Coastal sediments. --- Marine bacteria. --- Seawater --- Bacteria --- Marine microbiology --- Marine organisms --- Marine sediments --- Bacteriology

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Microorganisms (bacteria, archaea, microeukaryotes) in marine environments secrete a diverse array of exopolymeric substances that facilitate attachment to surfaces, the formation of organic colloids and larger aggregations of cells (marine snow), and that can influence many ocean, as well as global, processes. The aim of this Research Topic is to highlight recent advances in the sources, chemistry and function of these microbial-produced macromolecules. We encouraged original research and reviews on exopolymeric substances, from their sources, chemico-physiological properties, functions and ecosystem effects, and including their role in the Gulf of Mexico following the Deepwater Horizon oil spill disaster.

marine oil snow (MOS) --- exopolymers --- marine environment --- biological pump --- phytoplankton --- marine snow --- oceans --- marine bacteria --- exopolysaccharide substances (EPS) --- organic carbon --- marine oil snow (MOS) --- exopolymers --- marine environment --- biological pump --- phytoplankton --- marine snow --- oceans --- marine bacteria --- exopolysaccharide substances (EPS) --- organic carbon

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Marine bacteria --- Marine biotechnology --- Secondary metabolites --- Secondary metabolites --- synthetic polymers --- synthetic polymers --- Polysaccharides --- Polysaccharides --- Polymers --- Polymers --- Bacteria --- Biodiversity --- Biodiversity --- Biotechnology --- Biotechnology --- bacterial proteins --- bacterial proteins --- marine biology --- marine biology --- Marine environment --- Marine environment --- Marine resources --- Marine resources --- Bactéries marines. --- Biotechnologie marine.

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MARINE BIOLOGY --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE ENVIRONMENT --- MARINE ENVIRONMENT --- NATURAL RESOURCES --- MARINE ECOLOGY --- INTERTIDAL ZONE --- ESTUARIES --- REEFS --- PLANKTON --- MARINE ANIMALS --- MARINE PLANTS --- MARINE FUNGI --- MARINE BACTERIA --- MARINE FISHES --- MARINE MAMMALS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- TREATISES --- GEOLOGY --- PHYSICOCHEMICAL PROPERTIES --- ECOSYSTEMS --- ANTHROPOGENIC EFFECTS --- MARINE AREAS --- PROTISTA --- PROKARYOTES --- INVERTEBRATES --- REPTILES --- BIRDS --- MARINE BIOLOGY --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE ENVIRONMENT --- MARINE ENVIRONMENT --- NATURAL RESOURCES --- MARINE ECOLOGY --- INTERTIDAL ZONE --- ESTUARIES --- REEFS --- PLANKTON --- MARINE ANIMALS --- MARINE PLANTS --- MARINE FUNGI --- MARINE BACTERIA --- MARINE FISHES --- MARINE MAMMALS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- MARINE AREAS --- TREATISES --- GEOLOGY --- PHYSICOCHEMICAL PROPERTIES --- ECOSYSTEMS --- ANTHROPOGENIC EFFECTS --- MARINE AREAS --- PROTISTA --- PROKARYOTES --- INVERTEBRATES --- REPTILES --- BIRDS

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Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects.

Research & information: general --- sponge Monanchora pulchra --- pentacyclic guanidine alkaloids --- GH36 α-galactosidase --- GH109 α-N-acetylgalactosaminidase --- slow-binding irreversible inhibitor --- monanchomycalin B --- monanhocidin A --- normonanhocidin A --- Alzheimer′s disease --- BACE1 --- acetylcholinesterase --- in silico docking --- phlorotannins --- Ulva intestinalis --- ACE inhibitory peptide --- optimization --- purification --- structural identification --- molecular docking --- secondary metabolites --- Mycosphaerella sp. --- asperchalasine --- α-glucosidase --- kinase inhibitors --- drug development --- marine natural products --- inhibitor --- macroalgae --- marine fish --- protease --- Ulva ohnoi --- functional annotation --- structure–function relation --- natural products --- bioactives --- enzyme inhibition --- inactivation --- marine bacteria --- marine fungi --- marine sponges --- sponge Monanchora pulchra --- pentacyclic guanidine alkaloids --- GH36 α-galactosidase --- GH109 α-N-acetylgalactosaminidase --- slow-binding irreversible inhibitor --- monanchomycalin B --- monanhocidin A --- normonanhocidin A --- Alzheimer′s disease --- BACE1 --- acetylcholinesterase --- in silico docking --- phlorotannins --- Ulva intestinalis --- ACE inhibitory peptide --- optimization --- purification --- structural identification --- molecular docking --- secondary metabolites --- Mycosphaerella sp. --- asperchalasine --- α-glucosidase --- kinase inhibitors --- drug development --- marine natural products --- inhibitor --- macroalgae --- marine fish --- protease --- Ulva ohnoi --- functional annotation --- structure–function relation --- natural products --- bioactives --- enzyme inhibition --- inactivation --- marine bacteria --- marine fungi --- marine sponges