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This volume is the first truly international text to take the practitioner from the history, the physical basis, and the rationale of brachytherapy through to the techniques, the results, and the management of complications. It is also the first truly comprehensive and complete textbook of brachytherapy. The chapters on the physics of brachytherapy and the technical planning of internal and surface radiotherapy are designed to enhance the practitioner’s knowledge base and capabilities in this demanding specialty field. Disease site-specific chapters cover a wide range of applications, including ocular tumors, soft tissue sarcomas, cancers of the head and neck, skin, breast, lung, esophagus, and prostate, and gynecologic and anorectal malignancies. Each chapter incorporates the American and European guidelines and the text has been written from both perspectives by many of the most noted global experts in the field. A concluding chapter is devoted to brachytherapy quality assurance.

Radiology, MRI, Ultrasonography & Medical Physics --- Medicine --- Health & Biological Sciences --- Radioisotope brachytherapy. --- Radioisotopes --- Therapeutic use. --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Radioisotope therapy --- Implants, Artificial --- Therapeutic use --- Radiotherapy. --- Oncology  . --- Oncology. --- Tumors --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiological services

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This book provides a comprehensive insight into this special form of image-guided interventional therapy and its indications. It begins by introducing the fundamental principles of radiotherapy, the most up-to-date guidelines and the interdisciplinary aspects of the technique and then expands to more practical aspects such as therapy planning, indications and the use of the technique for certain tumor types, including liver metastases, rare tumors, cerebral malignancies and prostate tumors. Written and edited by pioneers in this technique, the chapter’s outline results and numerous illustrated case studies from the daily routine of daily clinical practice providing an insightful guidance to this relatively new but growing method. This is an indispensable guide for oncologists, radiation therapists and radiologists, but also general practitioners and all other specialties, which have an oncological focus.

Oncology  . --- Interventional radiology . --- Radiotherapy. --- Oncology. --- Interventional Radiology. --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiology, Interventional --- Therapeutics --- Tumors --- Radiological services --- Cancer --- Radioisotope brachytherapy. --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Implants, Artificial --- Radioisotopes --- Treatment --- Therapeutic use --- Braquiteràpia --- Radioteràpia --- Electrònica mèdica --- Electroteràpia --- Radioactivitat --- Radiologia mèdica --- Terapèutica fisiològica --- Radiocirurgia --- Fototeràpia --- Radi (Metall) --- Raigs X --- Braquioteràpia --- Endoradioteràpia --- Radioteràpia de contacte --- Radioteràpia intersticial

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This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 µm) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice.

Medicine & Public Health. --- Imaging / Radiology. --- Interventional Radiology. --- Nuclear Medicine. --- Hepatology. --- Oncology. --- Radiotherapy. --- Medicine. --- Medical radiology --- Interventional radiology. --- Nuclear medicine. --- Clinical medicine. --- Médecine --- Radiologie médicale --- Radiologie interventionnelle --- Médecine nucléaire --- Radiothérapie --- Médecine clinique --- Cancérologie --- Brachytherapy -- Methods. --- Embolization, Therapeutic -- Methods. --- Liver -- Cancer -- Treatment. --- Liver Neoplasms -- Radiotherapy. --- Radioisotope brachytherapy. --- Therapeutic embolization. --- Brachytherapy --- Liver Neoplasms --- Embolization, Therapeutic --- Digestive System Neoplasms --- Radiotherapy --- Hemostatic Techniques --- Liver Diseases --- Digestive System Diseases --- Neoplasms by Site --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Medicine --- Health & Biological Sciences --- Liver --- Cancer --- Treatment. --- Embolotherapy --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Radiology. --- Hemostasis, Surgical --- Interventional radiology --- Implants, Artificial --- Radioisotopes --- Therapeutic use --- Radiology, Medical. --- Oncology  . --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Therapeutics, Physiological --- Phototherapy --- Tumors --- Medicine, Clinical --- Atomic medicine --- Radioisotopes in medicine --- Radioactive tracers --- Radioactivity --- Radiology, Interventional --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Physiological effect --- Interventional radiology . --- Gastroenterology --- Radiological physics --- Physics --- Radiation

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This book reports the majority of lectures given during the NATO Advanced Study Institute ASI-982996, which was held at the European Scientific Institute of Archamps (ESI, Archamps – France) from November 15 to November 27, 2007. The ASI course was structured in two parts: the first was dedicated to what is often called “teletherapy”, i. e. radiotherapy with external beams, while the second focused on internal radiotherapy, also called “brachytherapy” or “curietherapy” in honour of Madame Curie who initiated the technique about a century ago. This ASI took place after the European School of Medical Physics, which devoted a 3 week period to medical imaging, a subject complementary to the topics of this book. Courses devoted to nuclear medicine and digital imaging techniques are collected in two volumes of the NATO Science Series entitled “Physics for Medical Imaging Applications” (ISBN 978-1-4020-5650-5) and “Molecular imaging: computer reconstruction and practice” (ISBN 978-1-4020- 8751-6). Every year in autumn ESI organises the European School of Medical Physics, which covers a large spectrum of topics ranging from Medical Imaging to Radiotherapy, over a period of 5 weeks. Thanks to the Cooperative Science and Technology sub-programme of the NATO Science Division, weeks four and five were replaced this year by the ASI course dedicated to “Physics of Modern Radiotherapy & Brachytherapy”. This allowed the participation of experts and students from 20 different countries, with diverse cultural background and professional experience.

Radioisotope brachytherapy. --- Radiotherapy. --- Radiotherapy --- Radioisotope brachytherapy --- Congresses --- Brachytherapy --- Therapeutics --- Publication Formats --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Publication Characteristics --- Biophysics --- Radiology, MRI, Ultrasonography & Medical Physics --- Biology --- Medicine --- Health & Biological Sciences --- Prostate --- Cancer --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Medicine. --- Radiology. --- Nuclear medicine. --- Biophysics. --- Biological physics. --- Biomedical engineering. --- Medicine & Public Health. --- Nuclear Medicine. --- Biophysics and Biological Physics. --- Biomedical Engineering. --- Imaging / Radiology. --- Clinical engineering --- Medical engineering --- Bioengineering --- Engineering --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Biological physics --- Medical sciences --- Physics --- Atomic medicine --- Radioisotopes in medicine --- Radioactive tracers --- Radioactivity --- Radiological physics --- Radiation --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Radiological services --- Physiological effect --- Implants, Artificial --- Radioisotopes --- Therapeutic use --- Radiology, Medical. --- Biological and Medical Physics, Biophysics. --- Biomedical Engineering and Bioengineering. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics