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This book discusses the immune system, and the avoidance of unhealthy habits and use of early detection as ways to delay the onset of serious diseases, and avoid the expense, time, effort, and side effects of standard treatments. Also introduces new therapeutic strategies in the development of targeted drugs and programmed cell death.

Immunotoxicology. --- Immunologic toxicology --- Immunotoxicity --- Immunopathology --- Immunopharmacology --- Toxicology --- Immunopathology. --- Immunotherapy. --- Immune System --- Autophagy --- Immunothérapie --- Système immunitaire --- Immunotoxicologie --- Immunopathologie --- physiology --- drug effects --- pathology --- Physiologie --- physiology. --- Immunology. --- Immunothérapie --- Système immunitaire

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Immunotoxicologie --- Immunotoxicology --- Immunotoxicology. --- Drug Toxicity. --- Immunity --- Immune System Diseases --- Xenobiotics --- Immunologic toxicology --- Immunotoxicity --- Immunopathology --- Immunopharmacology --- Toxicology --- drug effects. --- chemically induced. --- metabolism. --- Drug Toxicity --- chemically induced --- drug effects --- metabolism --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- adverse effects --- toxicity

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This single volume represents an additional text for students who require background information on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This second edition, thus, continues the unique format, dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to readers include a two-column format, glossaries of technical terms and an appendix of reference tables. The emphasis on illustrations from the first edition is maintained. The book, written by international experts, is suitable as a course textbook for students of various biomedical, chemical and pharmaceutical sciences and as a supporting text for medical and postgraduate students.

Immunopharmacology. --- Immunotoxicology. --- Immunodiagnosis. --- Immune system --- Effect of drugs on. --- Immunological system --- Anatomy --- Immunology --- Immunological diagnosis --- Clinical immunology --- Diagnosis, Laboratory --- Immunoassay --- Immunologic toxicology --- Immunotoxicity --- Immunopathology --- Immunopharmacology --- Toxicology --- Pharmacoimmunology --- Pharmacology --- Immunotoxicology --- Immunology. --- Toxicology. --- Cytology. --- Emerging infectious diseases. --- Allergy. --- Biochemistry. --- Pharmacology/Toxicology. --- Cell Biology. --- Infectious Diseases. --- Allergology. --- Medical Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Chemicals --- Medicine --- Poisoning --- Poisons --- Immunobiology --- Life sciences --- Serology --- Composition --- Pharmacology. --- Cell biology. --- Infectious diseases. --- Medical biochemistry. --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Immunotoxicity, Immune Dysfunction, and Chronic Disease is among the first books to illustrate the linkage between environmental risk factors (e.g., chemicals, drugs, diet, lifestyles), environmentally-induced immune dysfunction and the full range of resulting chronic diseases and conditions. There is a detailed discussion of specific immune-based chronic diseases and conditions that emerge in children and adults and affect different physiological systems. The book integrates a consideration of risk factors and specific immunotoxic alterations with disease outcomes. A significant number of diseases and conditions are discussed, such as systemic allergic diseases affecting the lung, skin and gastrointestinal tract, systemic autoimmune diseases (type 1 diabetes,multiple sclerosis and lupus) and chronic conditions that are not traditionally associated with chemically-mediated immunomodulation (depression, frailty, and atherosclerosis). Inflammatory dysregulation is a common thread that connects many of the diseases and conditions discussed in this book and provides a central focus. Individual chapters are organized by disease with the addition of chapters that provide integrative information on: 1) patterns of disease comorbidities and 2) the safety testing of chemicals and drugs to reduce the risk of immune dysfunction. Each chapter contains a summary of key points as well as recommendations when appropriate. The book stresses the benefits of identifying the environmental risk factors of immune-mediated chronic disease and the potential to reduce the prevalence of these diseases and conditions. This volume is a valuable resource for researchers, clinicians, risk assessors and regulators and students. .

Chronic diseases -- Immunological aspects. --- Immunology. --- Immunotoxicology. --- Chronic diseases --- Immunotoxicology --- Disease Attributes --- Diseases --- Immunoconjugates --- Hypersensitivity --- Disorders of Environmental Origin --- Noxae --- Toxic Actions --- Antibodies --- Pathologic Processes --- Immunoglobulins --- Chemical Actions and Uses --- Pathological Conditions, Signs and Symptoms --- Serum Globulins --- Chemicals and Drugs --- Immunoproteins --- Blood Proteins --- Globulins --- Proteins --- Amino Acids, Peptides, and Proteins --- Immunotoxins --- Environmental Illness --- Chronic Disease --- Immune System Diseases --- Medicine --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Internal Medicine --- Immunological aspects --- Immunological aspects. --- Immunologic toxicology --- Immunotoxicity --- Diseases, Chronic --- NCDs (Noncommunicable diseases) --- Non-communicable diseases --- Non-infectious diseases --- Noncommunicable diseases --- Medicine. --- Molecular biology. --- Pharmacology. --- Biomedicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Immunopathology --- Immunopharmacology --- Toxicology --- Toxicology. --- Immunobiology --- Life sciences --- Serology --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Immunopharmacology --- Immunotoxicology --- Allergy and Immunology --- Immune System --- Pharmacology --- drug effects --- Immunotoxins --- Communicable Diseases --- Immunopharmacology. --- Immunotoxicology. --- Immunology. --- Pharmacology. --- Toxicology. --- Immunotoxins. --- Allergy and Immunology. --- Communicable Diseases. --- Immunologic toxicology --- Immunotoxicity --- Pharmacoimmunology --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Pharmacologies --- Pharmaceutical Preparations --- Allergy Specialty --- Allergy, Immunology --- Immunology and Allergy --- Immunology, Allergy --- Immunology --- Specialty, Allergy --- Affinotoxins --- Chimeric Toxin --- Immunotoxin --- Monoclonal Antibody-Toxin Conjugates --- Toxin Carrier --- Toxin Conjugate --- Antibody-Toxin Conjugates --- Antibody-Toxin Hybrids --- Chimeric Toxins --- Cytotoxin-Antibody Conjugates --- Targeted Toxins --- Toxin Carriers --- Toxin Conjugates --- Toxin-Antibody Conjugates --- Toxin-Antibody Hybrids --- Toxins, Chimeric --- Toxins, Targeted --- Antibody Toxin Conjugates --- Antibody Toxin Hybrids --- Antibody-Toxin Conjugates, Monoclonal --- Carrier, Toxin --- Carriers, Toxin --- Conjugate, Toxin --- Conjugates, Antibody-Toxin --- Conjugates, Cytotoxin-Antibody --- Conjugates, Monoclonal Antibody-Toxin --- Conjugates, Toxin --- Conjugates, Toxin-Antibody --- Cytotoxin Antibody Conjugates --- Hybrids, Antibody-Toxin --- Hybrids, Toxin-Antibody --- Monoclonal Antibody Toxin Conjugates --- Toxin Antibody Conjugates --- Toxin Antibody Hybrids --- Toxin, Chimeric --- pharmacology --- Immunopathology --- Toxicology --- Disease Outbreaks --- Disease Transmission, Infectious --- Recombinant Fusion Proteins --- Antibodies, Bispecific --- Affinotoxin --- Antibody-Toxin Conjugate --- Antibody-Toxin Hybrid --- Cytotoxin-Antibody Conjugate --- Monoclonal Antibody-Toxin Conjugate --- Targeted Toxin --- Toxin-Antibody Conjugate --- Toxin-Antibody Hybrid --- Antibody Toxin Conjugate --- Antibody Toxin Hybrid --- Antibody-Toxin Conjugate, Monoclonal --- Conjugate, Antibody-Toxin --- Conjugate, Cytotoxin-Antibody --- Conjugate, Monoclonal Antibody-Toxin --- Conjugate, Toxin-Antibody --- Cytotoxin Antibody Conjugate --- Hybrid, Antibody-Toxin --- Hybrid, Toxin-Antibody --- Monoclonal Antibody Toxin Conjugate --- Toxin Antibody Conjugate --- Toxin Antibody Hybrid --- Toxin, Targeted