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This dissertation by Artai Pirouzram, presented at Linköping University, explores experimental and clinical studies on ruptured abdominal aortic aneurysm (rAAA). The research focuses on the effects of induced hypothermia on survival in cases of hemorrhagic shock caused by aortic rupture and examines the outcomes of endovascular aortic repair (EVAR) compared to traditional open surgery. Experimental models using anesthetized pigs were developed to study these effects, revealing that moderate induced hypothermia did not impair survival. Clinical studies on patients treated with EVAR showed improved survival rates compared to historical data, though accidental hypothermia was associated with worse outcomes. The work aims to differentiate between induced and accidental hypothermia, suggesting pathways for future research. Intended for medical professionals and researchers, the dissertation contributes valuable insights into advanced treatment methods for life-threatening vascular conditions.
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HEART ARREST, INDUCED --- HYPOTHERMIA, INDUCED --- PREOPERATIVE CARE --- MYOCARDIAL INFARCTION --- STANDARDS --- PREVENTION AND CONTROL --- HEART ARREST, INDUCED --- HYPOTHERMIA, INDUCED --- PREOPERATIVE CARE --- MYOCARDIAL INFARCTION --- STANDARDS --- PREVENTION AND CONTROL
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KIDNEY NEOPLASMS --- CARCINOMA --- NEPHRECTOMY --- HYPOTHERMIA, INDUCED --- RENAL ARTERY OBSTRUCTION --- SPLENORENAL SHUNT, SURGICAL --- SURGERY --- SURGERY --- KIDNEY NEOPLASMS --- CARCINOMA --- NEPHRECTOMY --- HYPOTHERMIA, INDUCED --- RENAL ARTERY OBSTRUCTION --- SPLENORENAL SHUNT, SURGICAL --- SURGERY --- SURGERY
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This book describes the evidence behind the application of Therapeutic Hypothermia on patients with injury to the brain and spinal cord, that includes ischemia reperfusion after cardiac arrest or asphyxiation, traumatic brain injury, acute ischemic stroke, hemorrhagic stroke, refractory intracranial hypertension, cerebral edema in acute liver failure, subarachnoid hemorrhage, as well as spinal cord injury. This book discusses the mechanisms by which therapeutic hypothermia can mitigate the pathophysiologies responsible for secondary brain injury, and provides information to help guide this treatment with regard to timing, depth, duration, and management of side-effects. The book also discusses the methods and technologies used to induce and maintain therapeutic hypothermia. It also describes how hypothermia can influence the ability to prognosticate these injured patients and provides grounds for future directions in the application of and research with therapeutic hypothermia.
Cold --- Therapeutic use. --- Crymotherapy --- Cryotherapy --- Hypothermia, Induced --- Hypothermia therapy --- Therapeutic use --- Cognition & cognitive psychology
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The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hypothermia was used for protection and preservation of the heart and entire organism during planned operative ischemia. Attempts were also made to use hypothermia for resuscitation from cardiac arrest and for management of head trauma. Therapeutic Hypothermia will provide a review of the subject, in particular, resuscitative hypothermia and include known mechanisms of action and results from both mechanistic and outcome laboratory studies and clinical trials. Cooling methods and potential side effects of hypothermia will be addressed as well as recommendations for future laboratory and clinical research. This volume will be of interest to both the researcher interested in therapeutic hypothermia as well as the clinician interested in the potential use of therapeutic hypothermia in their patient population. Samuel A. Tisherman is an Associate Professor in the Department of Surgery, the University of Pittsburgh, Pennsylvania, USA. Fritz Sterz is a Professor in Emergency Medicine at the University of Vienna, Vienna, Austria.
Cold --- Therapeutic use. --- Crymotherapy --- Cryotherapy --- Hypothermia, Induced --- Hypothermia therapy --- Therapeutic use --- Critical care medicine. --- Intensive / Critical Care Medicine. --- Intensive care --- Intensive medicine --- Medicine --- Emergency medicine --- Intensive care units
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Cells --- Cryopreservation of organs, tissues, etc --- Anhydrobiosis --- Biotechnology --- Cryopreservation. --- Dehydration. --- Hypothermia, Induced. --- Organ Preservation --- Tissue Preservation --- Biotechnology. --- Anhydrobiosis. --- Cryopreservation of organs, tissues, etc. --- Preservation --- methods. --- Preservation.
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Cryobiology --- Hypothermia --- Freeze-drying --- Cryoperservation --- periodicals. --- Cryoperservation. --- Cryobiologie --- Hypothermie --- Lyophilisation --- Cryobiology. --- Freeze-drying. --- Hypothermia. --- Hypothermy --- Low body temperature --- Lyophilization --- Freezing --- Low temperature biology --- Body temperature --- Cold --- Drying apparatus --- Refrigeration and refrigerating machinery --- Sublimation (Chemistry) --- Biology --- Cryopreservation of organs, tissues, etc. --- Low temperatures --- Physiological effect --- Hibernation Biology --- Low Temperature Biology --- Biologies, Low Temperature --- Biology, Hibernation --- Biology, Low Temperature --- Hibernation Biologies --- Low Temperature Biologies --- Temperature Biologies, Low --- Temperature Biology, Low --- Cryopreservation. --- Hypothermia, Induced. --- Cryonic Suspension --- Cryofixation --- Cryonic Suspensions --- Suspension, Cryonic --- Suspensions, Cryonic --- Cold Temperature --- Vitrification --- Induced Hypothermia --- Mild Hypothermia, Induced --- Moderate Hypothermia, Induced --- Targeted Temperature Management --- Therapeutic Hypothermia --- Hypothermia, Therapeutic --- Induced Mild Hypothermia --- Induced Mild Hypothermias --- Induced Moderate Hypothermia --- Induced Moderate Hypothermias --- Mild Hypothermias, Induced --- Moderate Hypothermias, Induced --- Targeted Temperature Managements --- Refrigeration --- Cryotherapy --- Cryopreservation --- Cryotherapy. --- Therapy, Cold --- Cold Therapy --- Cold Therapies --- Cryotherapies --- Therapies, Cold --- Hypothermia, Induced --- therapeutic use --- Freeze Drying.
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Cold --- Hypothermia, Induced --- Body temperature --- Hypothermia. --- Body Temperature. --- Hypothermia, Induced. --- Therapeutic use --- Regulation --- Regulation. --- Therapeutic use. --- Induced hypothermia --- Crymotherapy --- Cryotherapy --- Hypothermia therapy --- Regulation of body temperature --- Temperature adaptation --- Thermoregulation --- Organ Temperature --- Body Temperatures --- Organ Temperatures --- Temperature, Body --- Temperature, Organ --- Temperatures, Body --- Temperatures, Organ --- Hypothermia, Accidental --- Accidental Hypothermia --- Accidental Hypothermias --- Hypothermias --- Hypothermias, Accidental --- Body heat --- Temperature, Animal and human --- Temperature curve --- Anesthesia --- Surgery --- Therapeutics --- Biological control systems --- Temperature --- Cold Temperature --- Rewarming --- Cold-Shock Response --- Medical thermography --- Physical diagnosis --- Physiology --- Vital signs --- Animal heat --- Fever --- Heat --- Low temperatures --- Body Temperature --- Hypothermia
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