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Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the worlds leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. --

Aging --- Geriatric pharmacology. --- Pharmaceutical Preparations --- Longevity --- Geroscience --- Health aspects. --- Prevention. --- drug effects

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Pharmaceutical Preparations --- Drug Interactions --- Drug Therapy --- Aged. --- Drugs --- Geriatric pharmacology --- Posologie --- Pharmacologie gériatrique --- administration & dosage --- Dosage --- Handbooks, manuals, etc. --- Guides, manuels, etc. --- Pharmacologie gériatrique

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Geriatric pharmacology --- Drug interactions --- Pharmacokinetics --- Older African Americans --- Adult --- African Continental Ancestry Group --- Kinetics --- Pharmacological Processes --- Pharmacological Phenomena --- Therapeutics --- Ethnic Groups --- Phenomena and Processes --- Biochemical Phenomena --- Population Groups --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Age Groups --- Physiological Processes --- Continental Population Groups --- Persons --- Chemical Phenomena --- Named Groups --- Drug Therapy --- African Americans --- Drug Interactions --- Aged --- Medicine --- Health & Biological Sciences --- Geriatrics --- Age factors --- Medical care --- Drug use --- Geriatric pharmacology. --- Drug interactions. --- Age factors. --- Medical care. --- Drug use. --- African American aged --- African American older people --- Afro-American aged --- Older people, African American --- Age factors in pharmacokinetics --- Interactions, Drug --- Older people --- Aging --- Drugs --- Pharmacology --- Side effects

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This book summarizes the broad and rapidly evolving field of geriatric pharmacotherapy, which is becoming increasingly relevant for practicing physicians who care and prescribe medications for older patients. Around the globe, ageing populations are associated with an increased prevalence of chronic diseases. Older adults are often affected by multimorbidity, i.e., suffer from more than one chronic disease. The main consequence of multimorbidity is polypharmacy, which is commonly defined as the regular use of five or more medicines. Polypharmacy has now reached epidemic proportions in our societies, and is associated with an increased risk of drug-drug interactions, drug-disease interactions and adverse drug reactions. The management of polypharmacy in older patients with complex multimorbidity poses several challenges and needs to be based on specific knowledge and prescribing expertise. The aim of this book is to provide a comprehensive update on the field, and to share the expertise needed to optimize the management of pharmacotherapy in older patients.

Geriatric pharmacology. --- Pharmacology --- Geriatrics. --- Primary care (Medicine). --- Pharmacology. --- Nursing. --- Primary Care Medicine. --- Clinical nursing --- Nurses and nursing --- Nursing process --- Care of the sick --- Medicine --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Primary medical care --- Medical care --- Gerontology --- Older people --- Physiological effect --- Diseases --- Health and hygiene

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Medication use is the predominant form of health intervention in our society. And as we age, the likelihood of medication use increases dramatically, with more than 80 percent of those over age 65 using one or more medications. Along with that, the potential for medication errors also increases. Indeed adverse drug reactions (ADRs) and adverse drug events (ADEs) are a significant problem in older adults. Written in a practical format by contributors from Australia and the United States, Medication Management in Older Adults: A Concise Guide for Clinicians presents the available evidence on research interventions designed to reduce the incidence of medication errors in older adults, with a focus on acute, subacute, and residential (long-term) care settings. Because medication errors can occur at all stages in the medication process, from prescription by physicians to delivery of medication to the patient by nurses, and in any site in the health system, it is essential that interventions be targeted at all aspects of medication delivery. Chapters cover the principles of medical ethics in relation to medication management; common medication errors in the acute care sector; medication management in long-term care settings; nutrition and medications; the outcomes of a systematic review; dose form alterations; Electronic Health Records (EHR), Computerized Order Entry (COE), Beers criteria; and pharmacokinetics and pharmacodynamics. For those clinicians especially concerned with providing the best possible outcomes for their older adult patients, Medication Management in Older Adults: A Concise Guide for Clinicians is an invaluable resource and a significant contribution to the burgeoning literature on medication errors.

Geriatric pharmacology. --- Home care services -- Quality control. --- Medication errors -- Prevention. --- Older people -- Drug use. --- Older people -- Home care. --- Medication errors --- Older people --- Geriatric pharmacology --- Adult --- Patient Care Management --- Medicare Part D --- Pharmaceutical Services --- Drug Therapy --- Medical Errors --- Health Services --- Medicare --- Therapeutics --- Age Groups --- Insurance, Pharmaceutical Services --- Health Services Administration --- Medication Therapy Management --- Medication Errors --- Aged --- Insurance, Health --- Health Care --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care Facilities, Manpower, and Services --- Persons --- Named Groups --- Insurance --- Financing, Organized --- Economics --- Health Care Economics and Organizations --- Medicine --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Geriatrics --- Prevention --- Drug use --- Management --- Medical errors. --- Errors, Medical --- Medical mishaps --- Mishaps, Medical --- Medicine. --- Internal medicine. --- Geriatrics. --- Medicine & Public Health. --- Geriatrics/Gerontology. --- Internal Medicine. --- Pharmacology --- Errors, Scientific --- Practice --- Medicine, Internal --- Gerontology --- Diseases --- Health and hygiene