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Glycoconjugates --- Congresses. --- Congresses --- Cell Membrane. --- Cell membrane --- Cell Membrane --- Glycoconjugate --- Glycoproteins --- Glycosylation --- Golgi apparatus --- Oligosaccharides, conjugates
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The Golgi apparatus is more than 110 years in the center of interest and scientific debates. This book summarizes the data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy collecting a range of expertise, different points of view and different approaches.
Life Sciences. --- Cell Biology. --- Life sciences. --- Cytology. --- Sciences de la vie --- Cytologie --- Golgi Apparatus. --- Golgi-complex. --- Plant molecular biology. --- Golgi apparatus --- Organelles --- Cytoplasmic Structures --- Cytoplasm --- Intracellular Space --- Cellular Structures --- Cells --- Anatomy --- Golgi Apparatus --- Biology --- Health & Biological Sciences --- Cytology --- Golgi apparatus. --- Golgi bodies --- Golgi elements --- Golgi material --- Cell biology. --- Cell organelles --- Protoplasm --- Cell biology --- Cellular biology --- Cytologists
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Articles in this collection illustrate our recent progress in understanding Golgi biology, and also outline a specific set of yet unanswered Golgi-related questions. For example, exactly how do cargo and resident proteins travel to, through and out of the Golgi? What are the exact modes, carriers and molecular machineries of bi-directional Golgi trafficking? How are Golgi structure and its various functions modified during normal (differentiation, development, etc.) and abnormal (diseases, drugs, pathogens, etc.) circumstances?
Science: general issues --- Biology, life sciences --- Golgi apparatus --- Golgi dynamics --- Golgi structure --- Golgi function --- membrane trafficking
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The Golgi apparatus (GA) found as a ubiquitous component of all eukaryotic cells is typically comprised of stacks of 3 to 7 or more saccules called cisternae that consist of a lumen or central cavity surrounded by a membrane. At the peripheries of the saccules may be found perforations about 600 nM in diameter known as fenestrate. Such fenestrated margins are usually continuous with a system of vesicles and tubules. The individual stacks are organized into larger aggregate GA structures either side-by-side to form a complex ribbon with stacks interconnected by the peripheral tubules or in a dispersed arrangement with the stacks widely separated to appear almost as discrete units within the cytoplasm. The Golgi apparatus is often considered as the "distribution and shipping department" for the cell but also plays an equally important role in cell growth and membrane biogenesis. It modifies proteins and lipids (fats) to prepare them for export outside the cell or for delivery to the plasma membrane in support of membrane growth and replacement of membrane constituents lost due to turnover. The Golgi Apparatus traces the first 100 years of GA discovery from the first published accounts from Pavia, Italy, in 1898 to the Centenary Celebration in Pavia, Italy, in 1998 to our most recent discoveries. It summarizes the past 50 years beginning with the modern era of GA discovery initiated in 1954 and made possible by the advent of the electron microscope, methods of cell fractionation and biochemical analysis, leading up to the present era where focus has been on molecular biology. Emphasized are organization and function, the existence and importance of cisternal tubules, development of methods of GA isolation and subfractionation, biochemical analyses of highly purified GA fractions and comparison to equally highly purified reference fractions and their use in cell free systems analysis of membrane trafficking, the concept of GA function as part of an integrated system of internal endomembranes (the endomembrane system), evidence for differentiation of membranes across the stacks of GA cisternae, and flux of membrane constituents along the polarity gradient defined by membrane differentiation all culminating in the membrane maturation or flow differentiation model of GA function. More recent contributions to GA in cell growth (enlargement) and to cancer are summarized in final chapters.
Golgi Apparatus. --- Golgi apparatus --- Biology --- Health & Biological Sciences --- Cytology --- Golgi apparatus. --- Cell organelles. --- Organelles, Cell --- Golgi bodies --- Golgi elements --- Golgi material --- Life sciences. --- Cancer research. --- Neurosciences. --- Biochemistry. --- Plant biochemistry. --- Cell biology. --- Microscopy. --- Life Sciences. --- Cell Biology. --- Biochemistry, general. --- Biological Microscopy. --- Plant Biochemistry. --- Cancer Research. --- Cytoplasm --- Cell organelles --- Protoplasm --- Cytology. --- Oncology. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Tumors --- Analysis, Microscopic --- Light microscopy --- Micrographic analysis --- Microscope and microscopy --- Microscopic analysis --- Optical microscopy --- Optics --- Composition --- Cancer research --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics
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Cell membranes. --- Cytoplasmic filaments. --- Cytoplasm. --- Membrane cellulaire --- Microfilaments --- Cytoplasme --- Golgi apparatus. --- Appareil de Golgi. --- Mitochondries. --- Virus. --- Cell division. --- Division. --- Nucleolus. --- Nuclear membranes. --- Nucléoles. --- Enveloppe nucléaire. --- Cells --- Cell Biology --- Cell Physiological Phenomena --- Viruses --- Chromosomes --- Chromosomes. --- Cellules --- Cells. --- Cytology. --- Viruses. --- Cellules. --- Cytologie. --- Lysosomes. --- Mitochondria. --- Biology --- Cell physiology --- Biologie --- Physiologie --- Membrane cellulaire. --- Microfilaments. --- Cytoplasme. --- Division --- Cell Division. --- Cell Physiology --- Endoplasmic reticulum --- Cell Division --- Cell wall (microbial) --- Cell wall (plant) --- Chloroplasts --- Peroxisomes --- Cytology --- Nucléoles. --- Enveloppe nucléaire.
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Stap voor stap hypothese voor het ontstaan van een cel. Duidelijke opbouw.
Evolution (Biology) --- Cells --- Biological Processes --- Genetic Processes --- Biological Phenomena --- Genetic Phenomena --- Phenomena and Processes --- Biological Evolution --- Biology --- Health & Biological Sciences --- Evolution --- 573.5 --- 575.8 --- Golgi-apparaat --- biologie --- celkernen --- celleer --- chloroplasten --- cytologie --- eukaryoten --- evolutie --- evolutiemechanismen --- flagellen --- membranen --- mitochondriën --- prokaryoten --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Cell evolution --- Cellular evolution --- Life sciences. --- Medicine. --- Life Sciences, general. --- Biomedicine, general. --- Health Workforce --- Biosciences --- Sciences, Life --- Science --- EVOLUTION --- LIFE --- PROKARYOTES --- EUKARYOTES --- FLAGELLA --- PLASMA MEMBRANE --- NUCLEUS --- DIFFERENTIATION --- GOLGI APPARATUS --- MITOCHONDRIA --- PLASTIDS --- CILIA --- ORIGIN
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This volume takes a closer look how the cell organelles Golgi apparatus (also known as the Golgi complex or Golgi body), and centriole are structurally and functionally intertwined. Initially, it was believed that the role of Golgi complex is limited to the packaging and preparation for secretion of various cellular proteins, while the centriole participates in cell division and cilia formation. However, since their discovery nearly 200 years ago, it became clear that these two organelles are interacting, and that their functions are much more complex and far reaching than previously thought. Recent findings indicate that the Golgi–Centriole relationship may be important for directional protein transport, cell polarization and cell cycle progression. Current studies indicate that Golgi and centriole also participate in development and act as cellular and immunological sensors, and that their abnormalities lead to cell and developmental abnormalities, Alzheimer, cancer, various lipid disorders and neurological and immunological diseases in humans. This volume combines the latest information on the structure, molecular composition, and roles of Golgi and centriole in various cellular functions and diseases. The better understanding of the Golgi–centriole interactions may lead to the development of novel therapies for the treatment of various diseases, including cancer. .
Golgi apparatus. --- Centrioles. --- Developmental biology. --- Cell cycle. --- Cell membranes. --- Oncology. --- Cell physiology. --- Biochemistry. --- Developmental Biology. --- Cell Cycle Analysis. --- Membrane Biology. --- Cancer Research. --- Cell Physiology. --- Protein Science. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Cell function --- Cytology --- Physiology --- Tumors --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Development (Biology) --- Growth --- Ontogeny --- Composition --- Cell membranes . --- Cancer research. --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Cancer research --- Biological transport. --- Cancer. --- Cytology. --- Proteins. --- Developmental Biology and Stem Cells. --- Cytological Techniques. --- Membrane Trafficking. --- Cancer Biology. --- Cell Biology. --- Protein Biochemistry. --- Technique. --- Cell biology --- Cellular biology --- Cells --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Membrane transport --- Passive transport, Biological --- Physiological transport --- Transport, Biological --- Diffusion --- Osmosis
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