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Fatty Acids, Omega-3 --- Neoplasms --- Treatment Outcome. --- physiology. --- prevention & control.

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Eggs --- food analysis --- Fatty acids, Omega-3 --- Fatty acids, Omega-6 --- Eggs --- food analysis --- Fatty acids, Omega-3 --- Fatty acids, Omega-6

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Fatty Acids, Unsaturated --- Delirium, Dementia, Amnestic, Cognitive Disorders --- Fish Oils --- Evidence-Based Practice --- Clinical Medicine --- Dietary Fats, Unsaturated --- Medicine --- Health Occupations --- Dietary Fats --- Oils --- Mental Disorders --- Fatty Acids --- Fats --- Lipids --- Psychiatry and Psychology --- Disciplines and Occupations --- Chemicals and Drugs --- Evidence-Based Medicine --- Cognition Disorders --- Fatty Acids, Omega-3 --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Fatty Acids, Omega-3. --- drug therapy. --- methods.

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Omega-3 Delivery Systems: Production, Physical Characterization and Oxidative Stability offers the most recent updates for developing, characterizing, and stabilizing both traditional and novel omega-3 delivery systems, including their final incorporation into food matrices and physicochemical changes during digestion. The book brings chapters on novel omega-3 delivery systems (e.g., high-fat emulsions, Pickering emulsions, electrosprayed capsules, and solid lipid nanoparticles), the application of advanced techniques to evaluate physical and oxidative stabilities (e.g., SAXS, SANS, ESR, and super-resolution fluorescence microscopy), and new developments of food enrichment and physicochemical changes during digestion. The book provides a unique multidisciplinary and multisectoral approach, i.e., featuring authors from industry and academy. Long chain omega-3 polyunsaturated fatty acids (PUFA) present numerous health benefits; however, the consumption of natural products rich in omega-3 PUFA (e.g., fish, krill, and algae) is not enough to reach the daily-recommended values. Therefore, the food industry is highly interested in producing omega-3 fortified foods.

Omega-3 fatty acids. --- Fatty Acids, Omega-3. --- N-3 fatty acids --- Omega-3 EFA --- Omega-3 essential fatty acids --- Unsaturated fatty acids --- High-omega-3 fatty acid diet --- Fatty acids. --- Acids, Fatty --- Carboxylic acids

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Introduction : La dépression post-partum (DPP) est une réelle maladie reprise au sein du Diagnostic and Statistical Manual of Mental Disorder (DSM) qui toucherait environ 10 à 15% des femmes. Actuellement, il n’y a pas de cause mise en évidence, mais bien plusieurs facteurs de risque dont un faible taux sanguin d’acides gras oméga-3. Les femmes enceintes doivent être attentives à leur alimentation pour leur propre santé mais également pour le développement optimal de leur fœtus.

Objectifs : L’objectif de ce mémoire est d’étudier l’association entre les acides gras oméga-3 érythrocytaires maternels mesurés en début de grossesse et la dépression post-partum chez des femmes de la province de Liège. 

Matériel et méthode : La présente recherche a profité d’une étude sur l’évaluation des acides gras érythrocytaires en début de grossesse, menée au CHR de la Citadelle de Liège. Septante-trois participantes ont été recontactées par téléphone 1 an après leur accouchement. La DPP a été évaluée rétrospectivement à l’aide de l’échelle de Dunedin, adaptée par Stein & Van Den Akker.

Résultats : La prévalence de la DPP au sein de notre population est de 27.8%. Les résultats montrent une association significative entre les acides gras oméga-3 totaux ainsi que l’indice oméga-3 et le risque de dépression post-partum (p = 0.0011 et p = 0.0095, respectivement). L’analyse multivariée révèle que les facteurs significativement associés au risque de DPP sont la nationalité, la perception de l’état de santé après l’accouchement et les acides gras oméga-3 totaux.

Discussion et conclusion : Cette étude a permis de mettre en évidence que les femmes avec un taux sanguin suboptimal en acides gras oméga-3 totaux en début de grossesse sont 7.85 fois plus à risque de développer une dépression post-partum par rapport aux autres femmes. Il semblerait intéressant de réaliser un dosage des acides gras oméga-3 de manière systématique chez les femmes enceintes. Ce dernier permettrait une mise en garde des patientes avec un taux en acides gras oméga-3 suboptimal. Introduction : Postpartum depression (PPD) is a disease recognized as such by the Diagnostic and Statistical Manual of Mental Disorder (DSM). This disorder is said to affect 10 to 15% of the women. Up to now, no cause could be proven to be at the origin of it, but several risk factors, of which a low blood content of omega-3 fatty acids. Pregnant women must be careful with their diet for their own health but also to guarantee an optimal fetal development.

Objective : The goal of this thesis is to study the link between red blood cell omega-3 fatty acids in the mother counted at the beginning of the pregnancy and the postpartum depression in women from the region of Liege.

Materiel and methods : This research uses as a starting point a study on the evaluation of red blood cells fatty acids at the beginning of the pregnancy, conducted at the University hospital of the Citadelle de Liege. 73 attendants were contacted by phone one year after giving birth. The PPD was evaluated retrospectively thanks to the Dunedin Scale, adapted by Stein & Van Den Akker.

Results : PPD has a prevalence amongst our population of 27.8%. The results show a significant link between omega-3 fatty acids as well as the omega-3 index and the risk of PPD (p = 0.0011 et p = 0.0095, respectively). The multiple-ranging analysis shows that the factors that are strongly linked to the risk of PPD are nationality, one’s view on one’s health after giving birth and the total omega-3 fatty acids. 

Discussion and conclusion : This study allowed to underline that women with a suboptimal omega-3 fatty acids blood count at the beginning of a pregnancy have 7.85 times more probability to develop a postpartum depression compared to other women. Running systematic omega-3 fatty acids tests with pregnant women seem interesting. It would enable us to alert patients presenting a suboptimal omega-3 fatty acids level.

Dépression post-partum, acide gras polyinsaturé, acide gras oméga-3, érythrocytaire --- Postpartum depression, polyunsaturated fatty acids, omega-3 fatty acids, red blood cell-related/erythrocyte --- Sciences de la santé humaine > Santé publique, services médicaux & soins de santé