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Polymer composites represent the platform materials of the XXI century and are an important slice of the market in the production of modern plastics. Their design is based on adding a second component to the polymer matrix to enhance its properties. Among the various possible composites, organic–inorganic hybrid materials offer advantageous performance relative to either of the non-hybrid counterparts. The dramatic improvement of physical properties, compared with pure materials, in which inorganic particles or nanoparticles are inserted into an organic polymeric matrix, could bridge the gap between ceramics and polymers. We are interested in articles that explore polymer-based hybrid systems. The Special Issue topics include the synthesis and characterization of polymeric hybrid materials—hybrid composites in electronics and energy applications; hybrid composites in space applications; the biomedical application of hybrid polymeric materials.

History of engineering & technology --- Merox process --- dimethyl disulfide --- metal phthalocyanine --- activated carbon --- sodium methylmercaptide oxidation --- composite --- polymer --- crystalline graphite powder --- transmittance property --- shape-memory polymer --- nickel powder --- protrusive chain --- shape-memory effect --- surface morphology --- poly(lactic acid) --- flax fibers --- biocomposites --- predictive analytical model --- mechanical properties --- hybrid composite --- PCL --- TiO2 --- SiO2 --- FT-IR spectroscopy --- antibacterial behavior --- thermoset --- polyester --- bio-based --- poultry feathers --- fish gelatin methacrylate --- strontium-doped calcium silicate --- bone regeneration --- cell-laden scaffold --- bioprinting --- recycling material --- adhesion --- NiTi plate --- PMMA/NiTi composites --- surface features --- semiconductor nanocrystal --- hybrid --- solar cells --- organic semiconductor --- solution processed --- surfactant --- mechanico-thermal --- nanocomposites --- magneto-rheological (MR) --- filler --- elastomer --- micro-structure --- PA6 --- montmorillonite --- flammability --- surface modification --- thermal properties --- flame retardants --- hybrid composites --- chemical engineering --- Merox process --- dimethyl disulfide --- metal phthalocyanine --- activated carbon --- sodium methylmercaptide oxidation --- composite --- polymer --- crystalline graphite powder --- transmittance property --- shape-memory polymer --- nickel powder --- protrusive chain --- shape-memory effect --- surface morphology --- poly(lactic acid) --- flax fibers --- biocomposites --- predictive analytical model --- mechanical properties --- hybrid composite --- PCL --- TiO2 --- SiO2 --- FT-IR spectroscopy --- antibacterial behavior --- thermoset --- polyester --- bio-based --- poultry feathers --- fish gelatin methacrylate --- strontium-doped calcium silicate --- bone regeneration --- cell-laden scaffold --- bioprinting --- recycling material --- adhesion --- NiTi plate --- PMMA/NiTi composites --- surface features --- semiconductor nanocrystal --- hybrid --- solar cells --- organic semiconductor --- solution processed --- surfactant --- mechanico-thermal --- nanocomposites --- magneto-rheological (MR) --- filler --- elastomer --- micro-structure --- PA6 --- montmorillonite --- flammability --- surface modification --- thermal properties --- flame retardants --- hybrid composites --- chemical engineering

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Issues relating to the gender schism and its effect on the career advancement of women in the Academy, especially in the field of STEM disciplines, deserve our attention and the efforts of all the scientific community to mitigate the gender gap. In order to embrace gender equality, recognize the career progression of women, and to celebrate the achievements of women in the field of bioorganic chemistry, we present contributions both from highly renowned female scientists and young female researchers who are in the early stages of their careers. This Special Issue includes fifteen manuscripts, including eleven high-quality research articles and four comprehensive review articles in the area of bioorganic chemistry, published from mid-2020 to early 2022. The scope of this Special Issue covers a wide range of topics at the organic chemistry–biology interface, including the synthesis and derivatization of natural compounds and their analogues, and the investigation of their biological activities in the human health field (for instance as antitumorals, antioxidants and antimicrobial agents), as well as their possible application in the crop protection field as agrochemicals. An example of nanoparticle-based biomaterial is also included. The techniques employed, besides organic synthesis, are in silico studies (docking procedures and molecular modeling), FT-IR spectroscopy, laser diffraction, PET, fluorescence, STD-NMR studies, enzymatic evaluation, experiments on cell lines and in vivo studies on mice.

Technology: general issues --- Chemical engineering --- antibiotics --- biochemical studies --- iminosugars --- inhibitors --- insect trehalase --- trehalose --- in vivo studies --- mammalian trehalase --- natural compounds --- selectivity --- interrupted Nazarov cyclization --- pentacyclic steroids --- antiproliferative activity --- d-annulated steroids --- Lewis acid --- dental caries --- enamel remineralisation --- hydroxyapatite --- amelogenin --- amelogenin-derived peptides --- leucine-rich amelogenin peptides --- tyrosine-rich amelogenin peptides --- cannabidiol --- molecular mechanisms --- neurological diseases --- neuroprotective effects --- strigolactones --- Strigol --- anti-cancer --- antimicrobials --- sustainable agriculture --- α,α-difluorophosphonate --- deoxyxylulose phosphate reductoisomerase --- 1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) --- antimicrobial --- fosmidomycin --- isoprenoid biosynthesis --- 2-C-methyl-derythritol 4-phosphate (MEP) pathway --- multivalency --- gold nanoparticles --- enzyme inhibition --- Jack bean α-mannosidase --- aminoproline scaffold --- integrin targeting --- ligand design --- peptidomimetic synthesis --- leukocyte integrins --- BODIPY --- β-galactosidase activity --- PET --- fluorescent --- dispirooxindoles --- anticancer activity --- cytotoxicity --- 3D molecular docking --- p53/MDM2 interaction --- terpenes --- hydrazones --- penetration enhancers --- liposomes --- lipids --- stratum corneum --- laser diffraction --- fluorescence probe --- pyrene --- FT-IR spectroscopy --- heterohelicene --- chirality --- resolution --- enantiomers --- chiroptical --- screw-shaped compounds --- betulinic acid --- α-glucosidase --- inhibition mechanism --- postprandial hyperglycemia --- synergistic effect --- AMR --- persisters --- (p)ppGpp --- fragment screening --- thermal shift assay --- STD-NMR --- boron --- phthalimide --- benzamide --- glycosidase --- cancer --- boron neutron capture therapy --- n/a