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Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Radiopharmaceuticals. --- Single-photon emission computed tomography. --- Tomography, Emission. --- Diagnostic imaging --- Molecular diagnosis --- Nuclear medicine --- Tomography, Emission --- Tomography, Emission-Computed --- Indicators and Reagents --- Radionuclide Imaging --- Tomography --- Image Enhancement --- Image Interpretation, Computer-Assisted --- Laboratory Chemicals --- Diagnostic Imaging --- Photography --- Diagnostic Techniques, Radioisotope --- Specialty Uses of Chemicals --- Chemical Actions and Uses --- Diagnostic Techniques and Procedures --- Chemicals and Drugs --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Positron-Emission Tomography --- Tomography, Emission-Computed, Single-Photon --- Radiopharmaceuticals --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Technological innovations --- Molecular diagnosis. --- Radioisotope scanning. --- Radioisotopes in medical diagnosis. --- Diagnostic radioisotopes --- Radiodiagnosis --- Radioisotopes --- Radioisotope scintigraphy --- Radionuclide imaging --- Scintigraphy, Radioisotope --- Molecular diagnostics --- Diagnostic use --- Molecular aspects --- Medicine. --- Radiology. --- Nuclear medicine. --- Cardiology. --- Oncology. --- Neurology. --- Pathology. --- Medicine & Public Health. --- Nuclear Medicine. --- Imaging / Radiology. --- Radioactive tracers --- Radioactivity --- Radioisotopes in medical diagnosis --- Scanning systems --- Molecular biology --- Measurement --- Radiology, Medical. --- Oncology  . --- Nervous system --- Neuropsychiatry --- Heart --- Internal medicine --- Tumors --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Physiological effect --- Neurology . --- Radiological physics --- Physics --- Radiation