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Bifidobacterium --- Bifidobacterium --- Culture techniques --- Culture techniques --- culture media --- culture media --- Ascorbic acid --- Ascorbic acid --- Production --- Production --- Whey --- Whey --- Chlorydrate de cysteine --- Chlorydrate de cysteine

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plants --- plants --- Pathogens --- Pathogens --- Plant response --- Plant response --- Host parasite relations --- Host parasite relations --- Disease resistance --- Disease resistance --- genetic code --- genetic code --- Cysteine. --- Cysteine --- Peptide antifungal --- Defensin --- Peptide antifungal --- Defensin

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Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure‑function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research.

Cysteine proteinases -- Pathophysiology. --- Microbial enzymes. --- Pathogenic microorganisms. --- Cysteine proteinases --- Microbial enzymes --- Pathogenic microorganisms --- Natural Science Disciplines --- Organisms --- Peptide Hydrolases --- Hydrolases --- Disciplines and Occupations --- Enzymes --- Enzymes and Coenzymes --- Chemicals and Drugs --- Chemistry --- Bacteria --- Eukaryota --- Viruses --- Cysteine Proteases --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Pathophysiology --- Pathophysiology. --- Disease-causing microorganisms --- Micro-organisms, Pathogenic --- Pathogens --- Medicine. --- Molecular biology. --- Biomedicine. --- Biomedicine general. --- Molecular Medicine. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Microorganisms --- Medical microbiology --- Virulence (Microbiology) --- Microbiological chemistry --- Proteinase --- Health Workforce --- Biomedicine, general.

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Hydrogen sulfide (H2S), which was previously considered to be toxic, is now regarded as a burgeoning endogenous gaseous transmitter. H2S plays a vital role in the mechanism of response/adaptation to adverse environmental conditions as well as crosstalk with other signaling molecules, including ROS, by affecting the corresponding gene expression and subsequent enzyme activities. Both H2S and ROS are potent signaling molecules that can provoke reversible and irreversible oxidative post-translational modifications on cysteine residues of proteins such as sulfenylation or persulfidation, affecting the redox status and function of the target proteins. The dynamic interplay between persulfidation and sulfenylation occurring on cysteine residues is of great importance in response to environmental changes.The present Special Issue of IJMS has the aim of providing the most current findings on the function of signaling molecules, including H2S and ROS, in higher plants, and it is open to different types of manuscripts, including original research papers, perspectives, or reviews where either ROS, H2S, or related molecules could be involved at the biochemical or physiological levels.

Mathematics & science --- Biology, life sciences --- Molecular biology --- antioxidant defense systems --- Cd stress --- hydrogen sulfide --- melatonin --- oxidative stress --- transportation and sequestration --- nitric oxide --- abscisic acid --- Ca2+ --- hydrogen peroxide --- abiotic stresses --- signal transmitters --- stomatal movement --- persulfidation --- drought stress --- nitrate reductase --- l-cysteine desulfhydrase --- chilling stress --- indole-3-acetic acid --- signaling pathway --- calcium deficiency --- endogenous H2S --- reactive oxygen species --- ERF2-bHLH2-CML5 module --- postharvest storage quality --- tomato --- cysteine desulfhydrase --- leaf senescence --- ARF --- auxin --- cold stress --- cucumber --- DREB --- module --- resistance --- root growth --- heavy metal --- salt --- DES1 --- ABI4 --- protein stability --- Brassica rapa --- mercury --- selenium --- biotic stress --- abiotic stress --- salicylic acid --- jasmonic acid --- ethylene --- phytohormones --- Arabidopsis --- manganese stress --- L-cysteine desulfhydrase --- antioxidant enzyme --- Allium --- garlic --- gas detector --- ion-selective microelectrode --- isozymes --- RBOHs --- signaling networks --- n/a

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This Special Issue of Cancers focuses on new advances in the treatment of renal cell carcinoma, both surgical and pharmacological (and combinations of these), and novel approaches to tackle treatment resistance and improve our understanding of this phenomenon.

Medicine --- renal cell carcinoma --- autophagy --- hydroxychloroquine --- chloroquine --- ROC-325 --- cysteine cathepsins --- cysteine cathepsin inhibitors --- lysosome --- renal cancer --- metastatic renal cell carcinoma --- immune-based combination therapies --- network meta-analysis --- PD-L1 --- predictive --- biomarker --- treatment --- TKIs --- mRCC --- biomarkers --- soluble factors --- immunotherapy --- renal cell carcinoma (RCC) --- sunitib resistance --- artesunate (ART) --- Traditional Chinese Medicine (TCM) --- growth inhibition --- ferroptosis --- reactive oxygen species (ROS) --- clear cell renal cell carcinoma --- ccRCC --- RCC --- kidney cancer --- evolution --- evolutionary trajectory --- metastatic --- second line therapy --- renal cell cancer --- immune checkpoint inhibitors --- tyrosine kinase inhibitors --- individualization --- genomic signature --- transcriptomic analysis --- renal cell carcinoma --- autophagy --- hydroxychloroquine --- chloroquine --- ROC-325 --- cysteine cathepsins --- cysteine cathepsin inhibitors --- lysosome --- renal cancer --- metastatic renal cell carcinoma --- immune-based combination therapies --- network meta-analysis --- PD-L1 --- predictive --- biomarker --- treatment --- TKIs --- mRCC --- biomarkers --- soluble factors --- immunotherapy --- renal cell carcinoma (RCC) --- sunitib resistance --- artesunate (ART) --- Traditional Chinese Medicine (TCM) --- growth inhibition --- ferroptosis --- reactive oxygen species (ROS) --- clear cell renal cell carcinoma --- ccRCC --- RCC --- kidney cancer --- evolution --- evolutionary trajectory --- metastatic --- second line therapy --- renal cell cancer --- immune checkpoint inhibitors --- tyrosine kinase inhibitors --- individualization --- genomic signature --- transcriptomic analysis