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Ciliata --- Cilia and ciliary motion --- Phytoflagellates

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Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the budding yeast Saccharomyces cerevisiae, septin family GTPases are expressed and participate in the process of cytokinesis in most eukaryotes except higher plants. More than a dozen septin genes in mammals, together with various splice variants displaying tissue-specific expression patterns and flexible hetero-polymeric higher-order assembly achieve an unfathomable complexity superior to the other cytoskeletal components. Even though the initial studies in the septin field was restricted to their evolutionarily conserved role in cell division, strong expression of septins in the non-dividing cells of the brain generated great interest in understanding their role in neuronal morphogenesis and other aspects of cellular function. On one hand, recent developments indicate complex non-canonical roles for septins in diverse processes ranging from neuronal development to immune response and calcium signaling. On the other hand several lines of data including those from knockout models question the universal role for septins in animal cell cytokinesis. Mammalian hematopoietic cells seem to proliferate and efficiently undergo cytokinesis in the absence of pivotal septin proteins in a context-dependent manner. The lack of septin-dependence of hematopoiesis also opens the possibility of safely targeting septin-dependent cytokinesis for solid-tumor therapy. Thus the septin field is perfectly poised with novel roles for septins being discovered and the basic understanding on septin assembly and its canonical functions constantly revisited. The objective of this research topic was to provide an exclusive platform for discussing these rapid advances in the septin field. With a mixture of reviews and research articles encompassing diverse areas of septin research, ranging from the humble yeast model to human cancer, this ebook will be an interesting reading material for both experts as well as new comers to the septin field.

mutation --- cytoskeleton --- cytokinesis --- budding --- SOCE --- septin --- cancer --- GTPase --- yeast --- Cilia

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Cilia and ciliary motion --- Cytology --- Cils vibratiles --- Cytologie --- Periodicals --- Periodicals. --- Périodiques --- Cilia. --- Ciliary Motility Disorders. --- Cell Biology. --- Health aspects --- Cellular Biology --- Biologies, Cell --- Biologies, Cellular --- Biology, Cell --- Biology, Cellular --- Cell Biologies --- Cellular Biologies --- Ciliary Dyskinesia --- Immotile Cilia Syndrome --- Cilia Syndrome, Immotile --- Cilia Syndromes, Immotile --- Ciliary Dyskinesias --- Ciliary Motility Disorder --- Disorder, Ciliary Motility --- Disorders, Ciliary Motility --- Dyskinesia, Ciliary --- Dyskinesias, Ciliary --- Immotile Cilia Syndromes --- Syndrome, Immotile Cilia --- Syndromes, Immotile Cilia --- Cilium --- cell biology --- ciliary dysfunction --- Cilia and ciliary motion. --- Cytology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Microorganisms --- Epithelium --- Ciliopathies --- Motility --- Primary Ciliary Dyskinesia --- Ciliary Dyskinesia, Primary --- Dyskinesia, Primary Ciliary --- Histology. Cytology --- Motile Cilia --- Motile Cilium --- Nodal Cilia --- Nodal Cilium --- Primary Cilia --- Primary Cilium --- Cilia, Motile --- Cilia, Nodal --- Cilia, Primary --- Cilium, Motile --- Cilium, Nodal --- Cilium, Primary

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Paediatric medicine --- podocyte --- Nephrotic Syndrome --- ciliopathies --- Cilia --- polycystic kidney disease --- Genetics

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This collective work provides a reflexive reading of environmental democracy as a new method of governance of the contemporary ecological issues that declining biodiversity, climate change and sustainable development present. The authors examine the links between the environment and democracy by questioning the status of actors, the manner of their involvement, the various ways of mobilising knowledge and the mechanisms of dialogue and decision-making based on study cases observed in different national contexts (Italy, France, Ireland, Germany, the Netherlands, Russia, Canada and Brazil). This international approach sheds light on the means of appropriation of environmental democracy on a local level and its ability to promote universal characteristics or to standardise the connection to the environment and politics. The originality of this work comes, among other things, from its transversality, associating texts with differing theoretical outlooks and methodology in an innovative way. Through this perspective on-going processes of redefining environmental problems are revealed via the prisms of risks and uncertainty, thus assigning them a new role in aiding decision-making in a sociology that is in turn critical and committed.

biodiversity --- Cécilia --- Claeys --- climate change --- Democracy --- Environmental --- Facing --- governance --- Jacqué --- Marc --- Marie --- Mormont --- sustainable development --- Uncertainty