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Bioanalytical Chemistry
Authors: ---
ISBN: 0471544477 Year: 2004 Publisher: London ; New York, NY : Wiley-Interscience,

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Book
Forensic science progress.
Authors: --- --- --- ---
ISBN: 3540129375 0387129375 Year: 1988 Publisher: Berlin : Springer-Verlag,

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Thermal analysis methods have been introduced into forensic sciences only in recent times. Though thermoanalytical instruments have been available commercially for some decades it was not until the beginning of the seventies that forensic scientists became interested in them. At that time some state forensic science laboratories in the Federal Republic of Germany made use of differential thermal analysis for forensic soil investigations. The forensic science section of the city police of ZUrich, Switzerland, applied an instrument (differential thermal analysis and thermogravimetry) for various purposes. Investigations of fibers by means of differential scanning calorimetry were reported by the Centre of Forensic Sciences at Toronto, Canada, and on the characterization of candle-waxes by differential thermal analysis by the Metropolitan Police Forensic Science Laboratory, London, England. Later on some other insti­ tutions like the Bundeskriminalamt at Wiesbaden, Germany, or the Home Office Central Research Establishment at Aldermaston, England, purchased instruments for one or more of the following thermal analysis methods: differential thermal analysis or differential scanning calorimetry, thermogravimetry, and thermomechanical analysis. . But even now thermoanalytical instruments are not widespread in forensic science institutes and knowledge of their forensic potential seems to be limited. In the following chapters we will give a survey of the most important thermal analysis methods mentioned above, and on current forensic applications and/or fields of actual research efforts.


Book
Bioluminescence : methods and protocols
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ISBN: 9781071624555 9781071624531 9781071624753 9781071624739 Year: 2023 Publisher: New York, NY : Humana,

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This detailed collection explores recent advances in molecular imaging techniques involving bioluminescence, currently employed in biolaboratories around the world. Volume 2 delves into techniques for heterogeneous conjugates, protein fragment-complementation assays, BRET-based imaging, as well as instrumentation and software. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Bioluminescence: Methods and Protocols, Fourth Edition, Volume 2 presents practical guidance for researchers and technical staff on how to proceed with bioluminescence studies in their laboratories.


Book
Forensic science progress.
Authors: --- --- --- ---
ISBN: 354053203X 038753203X Year: 1991 Publisher: Berlin : Springer-Verlag,

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The range at which a weapon has been fired is an important measurement for the reconstruction of firearms offenses (murder, suicide, accident). All changes caused by a shot and which vary according to the distance from the weapon are suitable in principle for determining this distance. However, some procedures are very elegant in theory but hardly applicable in practice. The constructions of ammunition and the sequence of events during a shot are dealt with first as this knowledge forms a basis for understanding the various methods. The individual zones (classes) of firing distances (contact shot, intermediate shot, distance shot) are described. In this connection, the morphological methods for determining the firing distance are discussed. From the shape and size of the powder residue distribution (soot stains, powder tattooing) and with the knowledge of the weapon and ammunition, the distance from the target can be elucidated. In this chapter, the methods of making an invisible distribution visible are also dealt with. In order to determine the range of the shot from the appearance of the wound no complicated apparatus is necessary. One can judge with the naked eye. These procedures have a great advantage over the methods discussed in the following chapter in that they give stronger proof. They are more vivid and convincing for the uninitiated (judge or jury) than abstract measurements obtained by scientific devices.


Book
Forensic science progress.
Authors: --- ---
ISBN: 3540184473 0387184473 Year: 1988 Publisher: Berlin : Springer-Verlag,

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Competitive binding techniques such as radioimmunoassay (RIA) are widely used to measure an enormous variety of compounds in biological fluids. Current methods have 1 2 arisen from the pioneering work ofYalow and Berson in the U. S. A. and Ekins in the u. K. Much of the early development was concerned with the analysis of protein hormones, and nearly a decade passed before attention focussed also on small molecules such as steroids and drugs. The potential of immunoassay methods for drug monitoring in clinical and forensic laboratories and in addict treatment programmes resulted in the commercial production of immunoassays for various therapeutic and abused drugs, making the technique available to laboratories lacking the facilities to raise their own antisera and synthesise labelled compounds. However, commercial assays are not only expensive but are restricted in range, and so it is advantageous for a forensic laboratory to have the capability to devise "in-house" immunoassays suited to its particular requirements. This chapter describes the theory and practice of RIA in forensic drug analysis. Much of the theory and some of the practice are applicable to immunoassays in which non­ isotopic labels are used, but such assays are not described in detail since, to date, the versatility and sensitivity of RIA have made it the immunoassay technique of choice in forensic toxicology. The particular advantages of RIA are its sensitivity and the fact that samples such as haemolysed blood can be assayed with little or no prior preparation.


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Forensic science progress.
Authors: --- ---
ISBN: 354051841X 038751841X Year: 1990 Publisher: Berlin : Springer-Verlag,

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Methamphetamine is one of the most widely abused stimulants and together with amphetamine has led to serious social problems. Numerous papers in the fields of medicine, toxicology, pharmacology, sociology, etc. have appeared. In Japan for example about 20,000 to 22,000 persons have been arrested in recent years on suspicion of abuse, smuggling or illegal manufacture of drugs. In other countries, stimulant drugs also present social problems and efforts have been directed toward prevention. Although marked development of analytical techniques in the field of forensic sciences has been achieved, there is a need for a continuous review of recent advances. A review of studies on methamphetamine has therefore been made from the standpoint of forensic toxicology and legal medicine. Attention has been directed to biological samples because analyses and interpretation for the purpose of t.oxicological and As a detailed survey on abuse drugs involving clinical practice are important. 1 methamphetamine and amphetamine has been made by Fishbein and covered the time before 1980, we refer only to data and events appearing after 1980.


Book
Biochimie clinique
Authors: --- ---
ISBN: 2853341291 285334259X 2853341887 Year: 1977 Publisher: Villeurbanne : Simep,


Book
Analytical techniques in biosciences
Authors: --- --- --- ---
ISBN: 9780128226544 9780128227992 0128227990 0128226544 Year: 2022 Publisher: London San Diego, CA

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'Analytical Techniques in Biosciences : From Basics to Applications" presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry.The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences.

Evaluation of analytical methods in biological systems.
Author:
ISBN: 9780444422071 0444422072 1281778370 9781281778376 9786611778378 6611778373 0080875521 9780080875521 0444417443 0444425349 Year: 1984 Volume: v. 4, pt. B Publisher: Amsterdam New York Elsevier

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Electroanalysis as a representative of the wet-chemical methods has many advantages, such as: selectivity and sensitivity, nothwithstanding its inexpensive equipment; ample choice of possibilities and direct accessibility, especially to electronic and hence automatic control even at distance; automated data treatment; and simple insertion, if desirable, into a process-regulation loop. There may be circumstances in which an electroanalytical method, as a consequence of the additional chemicals required, has disadvantages in comparison with instrumental techniques of analysis; however the above-mentioned advantages often make electroanalysis the preferred approach for chemical control in industrial and environmental studies. This book provides the reader with a full understanding of what electroanalysis can do in these fields. It presents on the one hand a systematic treatment of the subject and its commonly used techniques on a more explanatory basis, and on the other it illustrates the practical applications of these techniques in chemical control in industry, health and environment. As such control today requires the increasing introduction of automation and computerization, electroanalysis with its direct input and/or output of electrical signals often has advantages over other techniques especially because recent progress in electronics and computerization have greatly stimulated new developments in the electroanalysis techniques themselves. Part A looks systematically at electroanalysis while more attention is paid in Part B to electroanalysis in non-aqueous media in view of its growing importance. The subject is rounded off in Part C by some insight into and examples of applications to automated chemical control.


Book
Nanomaterials for Liquid Chromatography and Laser Desorption/Ionization Mass Spectrometry
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ISBN: 9783319077499 3319077481 9783319077482 331907749X Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Tian Lu's dissertation describes major advances in ultrathin-layer chromatography (UTLC), liquid chromatography and surface-assisted laser desorption ionization (SALDI), and matrix-enhanced SALDI (ME-SALDI) mass spectrometry. Lu describes the fabrication of electrospun polyvinyl alcohol (PVA) UTLC plates using an in-situ crosslinking electrospinning technique. The author improved the efficiency of PVA plates greatly compared to the efficiency of silica HPTLC plates.  Also highlighted in this thesis is an edge-plane based ordered-carbon surface that provides unique selectivity in liquid chromatography. Further developments include polar analytes, such as amino acids, nucleotides and nucleosides which can be well-retained and separated in the edge-plane ordered-carbon stationary phase. Also, the author studied and detected mass spectra of organic polymers as high as 900,000 Da, the highest molecular weight that has been studied by SALDI to date using the carbon nanofibrous substrate. This thesis has led to a number of publications in high-impact journals.

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