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Leading neuroscientist Gordon M. Shepherd embarks on a paradigm-shifting trip through the "human brain flavor system," laying the foundations for a new scientific field: neurogastronomy. Challenging the belief that the sense of smell diminished during human evolution, Shepherd argues that this sense, which constitutes the main component of flavor, is far more powerful and essential than previously believed.Shepherd begins Neurogastronomy with the mechanics of smell, particularly the way it stimulates the nose from the back of the mouth. As we eat, the brain conceptualizes smells as spatial patterns, and from these and the other senses it constructs the perception of flavor. Shepherd then considers the impact of the flavor system on contemporary social, behavioral, and medical issues. He analyzes flavor's engagement with the brain regions that control emotion, food preferences, and cravings, and he even devotes a section to food's role in drug addiction and, building on Marcel Proust's iconic tale of the madeleine, its ability to evoke deep memories. Shepherd connects his research to trends in nutrition, dieting, and obesity, especially the challenges that many face in eating healthily. He concludes with human perceptions of smell and flavor and their relationship to the neural basis of consciousness. Everyone from casual diners and ardent foodies to wine critics, chefs, scholars, and researchers will delight in Shepherd's fascinating, scientific-gastronomic adventures.

Brain --- Nose --- Olfactory Perception --- Smell --- Taste Perception --- Taste --- Physiology. --- physiology. --- Physiological aspects. --- Taste. --- Chemical senses. --- Chemoreception --- Senses and sensation --- Chemoreceptors --- Gustation --- Tasting (Physiology) --- Chemical senses --- Drinking behavior --- Tongue --- Food preferences

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Nervous System Physiological Phenomena --- Membrane Potentials --- Neuronal Plasticity --- Behavior --- Neurobiology --- Molecular neurobiology --- physiology --- Behavior - physiology

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This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. Wilfrid Rall was a pioneer in establishing the integrative functions of neuronal dendrites that have provided a foundation for neurobiology in general and computational neuroscience in particular. This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. It brings together Rall's work over more than forty years, including his first papers extending cable theory to complex dendritic trees, his ground-breaking paper introducing compartmental analysis to computational neuroscience, and his studies of synaptic integration in motoneurons, dendrodendritic interactions, plasticity of dendritic spines, and active dendritic properties. Today it is well known that the brain's synaptic information is processed mostly in the dendrites where many of the plastic changes underlying learning and memory take place. It is particularly timely to look again at the work of a major creator of the field, to appreciate where things started and where they have led, and to correct any misinterpretations of Rall's work. The editors' introduction highlights the major insights that were gained from Rall's studies as well as from those of his collaborators and followers. It asks the questions that Rall proposed during his scientific career and briefly summarizes the answers.

Dendrites --- Dendrites. --- Models, Theoretical. --- Models, Theoretical --- Neurons --- Cell Surface Extensions --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Nervous System --- Cells --- Cellular Structures --- Anatomy --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Anatomies --- Cell Components --- Cell Component --- Cellular Structure --- Component, Cell --- Components, Cell --- Structure, Cellular --- Structures, Cellular --- Cell --- Cell Biology --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Cell Surface Projections --- Cell Surface Protrusions --- Cellular Protrusions --- Cell Membrane Extensions --- Cell Membrane Projections --- Cell Membrane Protrusions --- Cell Membrane Extension --- Cell Membrane Projection --- Cell Membrane Protrusion --- Cell Surface Extension --- Cell Surface Projection --- Cell Surface Protrusion --- Cellular Protrusion --- Extension, Cell Membrane --- Extension, Cell Surface --- Extensions, Cell Membrane --- Extensions, Cell Surface --- Membrane Extension, Cell --- Membrane Extensions, Cell --- Membrane Projection, Cell --- Membrane Projections, Cell --- Membrane Protrusion, Cell --- Membrane Protrusions, Cell --- Projection, Cell Membrane --- Projection, Cell Surface --- Projections, Cell Membrane --- Projections, Cell Surface --- Protrusion, Cell Membrane --- Protrusion, Cell Surface --- Protrusion, Cellular --- Protrusions, Cell Membrane --- Protrusions, Cell Surface --- Protrusions, Cellular --- Surface Extension, Cell --- Surface Extensions, Cell --- Surface Projection, Cell --- Surface Projections, Cell --- Surface Protrusion, Cell --- Surface Protrusions, Cell --- Nerve Cells --- Cell, Nerve --- Cells, Nerve --- Nerve Cell --- Neuron --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Computer Simulation --- Systems Theory --- Dendrite --- Mathematical models. --- Mathematical models --- NEUROSCIENCE/General --- Neurology and clinical neurophysiology