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Biopharmaco-efficiency. Pharmacokinetics --- 619 --- Diergeneeskunde --- Disease Models, Animal --- Animal Disease Model --- Animal Disease Models --- Disease Model, Animal --- Animals, Laboratory --- Models, Biological --- Diseases --- Animal models. --- Disease Models, Animal.
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The collection of systems represented in the Sourcebook of Models for Biomedical Research reflect the diversity and utility of models that are used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. Some models have the advantage that the reproductive, mitotic, development or aging cycles are rapid compared with those in humans; others are utilized because individual proteins may be studied in an advantageous way and have human homologs. Other organisms are facile to grow in laboratory settings, lend themselves to convenient analyses, have defined genomes or present especially good human models of human or animal disease. The Sourcebook of Models for Biomedical Research is a comprehensive and extensive collection of these important medical parallels. While the entire book is not devoted to the remarkable success of the genomic programs, this work is well represented and indexed within these pages. This volume will be an invaluable resource for pharmaceutical and academic researchers across a wide range of biological fields.
Animal models in research. --- Medicine --- Research. --- Biomedical research --- Medical research --- Animal experimentation --- Biological models --- Laboratory animals --- Research --- Endocrinology. --- Medicine. --- Neurosciences. --- Biomedicine general. --- Molecular Medicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Internal medicine --- Hormones --- Health Workforce --- Endocrinology . --- Molecular biology. --- Biomedicine, general. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology
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Continuing progress has been made in understanding the brain at the molecular, anatomic, and physiological levels in the years following the "Decade of the Brain," with the results providing insight into the underlying basis of many neurological disease processes. In Neuroscience in Medicine, Third Edition, a distinguished panel of basic and clinical investigators, noted for their teaching excellence, provide thoroughly updated and revised chapters to reflect these remarkable advances. Designed specifically for medical students and allied health professionals, this up-to-date edition alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relate that science to the understanding of neurological disorders and their treatment. These popular and now expanded "clinical correlations" cover, in detail, disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Neuroscience in Medicine, Third Edition provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as clearly demonstrating their emerging diagnostic and therapeutic importance.
Medicine. --- Human physiology. --- Neurosciences. --- Neurology. --- Neurobiology. --- Biomedicine. --- Human Physiology. --- Neurosciences --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Physiology --- Human body --- Diseases --- Neurophysiology. --- Pathophysiology. --- Neurobiology --- Neurology .
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Biological techniques --- Enzymology --- Pathological endocrinology --- Brain peptides --- Hormonal peptides --- Hormones peptidiques --- Neuropeptiden --- Neuropeptides --- Peptide hormonen --- Peptide hormones --- Peptiden [Neuro] --- Peptides [Neuro] --- Polypeptide hormones --- Hormones --- Physiological effect --- Metabolism --- Regulation
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Eiwit [Groene fluorescente ] --- GFP --- Green fluorescent protein --- Groene fluorescente eiwit --- Protéine fluorescente verte --- Protéine verte fluorescente --- FLUORESCENT DYES --- PROTEINS --- BIOLOGICAL STUDIES --- Enzymologie
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Confocal microscopy --- Confocale microscopie --- Microscopie confocale --- Animal tissue --- Bacteria --- Biological materials --- Confocal laser scanning microscopy --- Viruses
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Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine. The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer
Diseases -- Animal models. --- Laboratory animals. --- Pathology, Experimental. --- Diseases --- Laboratory animals --- Pathology, Experimental --- Models, Animal --- Models, Biological --- Animal Diseases --- Investigative Techniques --- Models, Theoretical --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disease Models, Animal --- Animal models --- Animal models. --- Experimental pathology --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal disease models --- Disease models, Animal --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Animal models in research --- Medicine, Comparative --- Medicine, Experimental --- Pathology, Comparative
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Neurosciences. --- Nervous System Physiological Phenomena. --- Nervous System Physiological Phenomena --- Nervous System Diseases --- Translational Medical Research --- Knowledge Translation --- Translational Medical Science --- Translational Medicine --- Translational Research, Medical --- Translational Research --- Knowledge Translations --- Medical Research, Translational --- Medical Science, Translational --- Medical Sciences, Translational --- Medical Translational Research --- Medicine, Translational --- Research, Medical Translational --- Research, Translational --- Research, Translational Medical --- Science, Translational Medical --- Sciences, Translational Medical --- Translation, Knowledge --- Translational Medical Sciences --- Translational Researchs --- Translations, Knowledge --- National Center for Advancing Translational Sciences (U.S.) --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Nervous System Physiological Concepts --- Nervous System Physiological Phenomenon --- Nervous System Physiological Process --- Physiology, Nervous System --- Nervous System Physiologic Processes --- Nervous System Physiological Processes --- Nervous System Physiology --- System Physiology, Nervous --- Nervous System --- physiology --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system
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For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion. Concise yet comprehensive, Endocrinology: Basic and Clinical Principles, Second Edition offers students, clinicians, and scientists access to the entire spectrum of endocrinological knowledge, authoritatively illuminating the basic scientific principles underlying every aspect of hormone secretion and action, and leading the reader towards a full understanding of the pathogenesis and management of human endocrine disease.
Endocrinology. --- Hormones. --- Endocrine glands --- Diseases. --- Internal medicine --- Hormones --- Clinical endocrinology --- Endocrine diseases --- Hormonal disorders --- Catecholamines --- Endocrinology --- Secretion
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