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Orthopedic surgery --- Orthopedic surgery. --- Orthopedics.

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"This edition represents the scientific basis of orthopaedic surgery as of 2020. It is intended to inform clinical decision making by providing the basic sciences in a clinically relevant context. The production of the fifth edition of Orthopaedic Basic Science was a substantial undertaking contributed to by each of the authors. The author list is comprised of senior scientists and clinicians, and rising stars, a healthy mixture that reflects well on both sustained personal commitments and expectations for the future. Reflecting the growth in orthopaedic scientific information, all the previously included chapters have been revised and many new chapters have been added. Molecular biology has been refocused to emphasize the role of epigenetics. Biomaterials, repair, and tissue engineering are also emphasized. The significance of articular crosstalk is presented together with new chapters on joint biology and osteoarthritis. Consideration of gender differences in preclinical and clinical studies recognizes the spectrum of biological responses and the presentation of metabolic bone diseases acknowledges the importance of secondary fracture prevention. A completely redone section on the generation of clinical information recognizes advances in methodology, the assessment of large databases and the growth of registries, and best-practice guidelines"--

Musculoskeletal Physiological Phenomena --- Musculoskeletal Diseases --- Musculoskeletal System --- Orthopedic Procedures --- Chirurgie orthopédique --- Appareil locomoteur --- Chirurgie orthopédique. --- surgery --- physiopathology --- Aspect physiologique. --- Maladies --- Thérapeutique. --- Physiopathologie. --- Musculoskeletal Physiological Phenomena. --- Orthopedic Procedures. --- surgery. --- physiopathology. --- Musculoskeletal system --- Musculoskeletal Systems --- System, Musculoskeletal --- Systems, Musculoskeletal --- Musculoskeletal Development --- Orthopedic Rehabilitation Surgery --- Orthopedic Surgical Procedures --- Orthopedic Surgery --- Surgery, Orthopedic --- Orthopedic Procedure --- Orthopedic Rehabilitation Surgeries --- Orthopedic Surgeries --- Orthopedic Surgical Procedure --- Procedure, Orthopedic --- Procedure, Orthopedic Surgical --- Procedures, Orthopedic --- Procedures, Orthopedic Surgical --- Rehabilitation Surgeries, Orthopedic --- Rehabilitation Surgery, Orthopedic --- Surgeries, Orthopedic --- Surgeries, Orthopedic Rehabilitation --- Surgery, Orthopedic Rehabilitation --- Surgical Procedure, Orthopedic --- Surgical Procedures, Orthopedic --- Orthopedics --- Orthopedic Disorders --- Musculoskeletal Disease --- Orthopedic Disorder --- Musculoskeletal Physiologic Process --- Musculoskeletal Physiological Concepts --- Musculoskeletal Physiological Phenomenon --- Physiology, Musculoskeletal --- Musculoskeletal Physiologic Processes --- Musculoskeletal Physiological Process --- Musculoskeletal Physiological Processes --- Musculoskeletal Physiology --- Concept, Musculoskeletal Physiological --- Concepts, Musculoskeletal Physiological --- Musculoskeletal Physiological Concept --- Phenomena, Musculoskeletal Physiological --- Phenomenon, Musculoskeletal Physiological --- Physiologic Process, Musculoskeletal --- Physiologic Processes, Musculoskeletal --- Process, Musculoskeletal Physiologic --- Process, Musculoskeletal Physiological --- Processes, Musculoskeletal Physiologic --- Processes, Musculoskeletal Physiological --- Pathophysiology --- physiology --- Pathophysiology. --- Musculoskeletal Diseases.