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Cannabis --- Cannabinoids --- Cannabis. --- Cannabinoids. --- Hallucinogenic drugs --- Terpenes --- Cannabis gigantea --- Cannabis indica --- Cannabis sativa --- Gallow grass --- Cannabaceae --- Marijuana --- Hemp Plant --- Marihuana --- Bhang --- Ganja --- Hashish --- Hemp --- Bhangs --- Cannabi --- Cannabis indicas --- Cannabis sativas --- Ganjas --- Hashishs --- Hemp Plants --- Hemps --- Marihuanas --- Marijuanas --- Plant, Hemp --- Plants, Hemp --- indicas, Cannabis --- sativas, Cannabis --- Medical Marijuana --- Receptors, Cannabinoid --- Cannabinoid Receptor Agonists --- Cannabinoid --- Human medicine
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"Journal of Cannabis Research is an international open access journal which covers all aspects of cannabis, encompassing not only clinical and scientific research, but also research into social, economic, legal, environmental and ethical impacts of cannabis. Our goal is to provide an outlet for experts across disciplines, driving public discourse and innovation around this timely issue."
Cannabinoids --- Cannabis --- Cannabis. --- Cannabinoids. --- Therapeutic use --- Social aspects --- Physiological effect --- therapeutic use. --- Therapeutic use. --- Physiological effect. --- Hallucinogenic drugs --- Terpenes --- Cannabis gigantea --- Cannabis indica --- Cannabis sativa --- Gallow grass --- Cannabaceae --- Marijuana --- Receptors, Cannabinoid --- Cannabinoid Receptor Agonists --- Hemp Plant --- Marihuana --- Bhang --- Ganja --- Hashish --- Hemp --- Bhangs --- Cannabi --- Ganjas --- Hashishs --- Hemp Plants --- Hemps --- Plant, Hemp --- Plants, Hemp --- Medical Marijuana --- Cannabinoid --- cannabis --- cannabinoids --- hemp --- public health
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As research has progressed, the cannabinoid CB 1 and CB 2 receptors have expanded significantly in importance within the neuroscience mainstream. In The Cannabinoid Receptors, leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structure activity relationships, the molecular pharmacology of the cannabinoid receptors and the endocannabinoid system, and ultimately, the whole animal pharmacology and therapeutic applications for cannabinoid drugs. Adding to those key topics, the book also examines the current direction of the field with chapters on new putative cannabinoid receptors and challenges for future research. As a part of The Receptors ™ series, this volume highlights its receptor with the most thorough, focused and essential information available. Comprehensive and cutting-edge, The Cannabinoid Receptors serves as an ideal guidebook to what continues to be a fascinating and vital field.
Cannabinoiden. --- Endocannabinoids. --- Medicine. --- Neurobiology. --- Neurosciences. --- Receptoren. --- Receptors, Cannabinoid. --- Toxicology. --- Cannabinoids --- Terpenes --- Receptors, G-Protein-Coupled --- Neurotransmitter Agents --- Molecular Mechanisms of Pharmacological Action --- Receptors, Cell Surface --- Hydrocarbons --- Organic Chemicals --- Pharmacologic Actions --- Membrane Proteins --- Proteins --- Chemicals and Drugs --- Chemical Actions and Uses --- Amino Acids, Peptides, and Proteins --- Endocannabinoids --- Receptors, Cannabinoid --- Medicine --- Health & Biological Sciences --- Neurology --- Receptors --- Cannabis. --- Receptors. --- Cannabis gigantea --- Cannabis indica --- Cannabis sativa --- Gallow grass --- Molecular biology. --- Pharmacology. --- Proteins. --- Biomedicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Cannabaceae --- Marijuana --- Cannabis --- Hallucinogenic drugs --- Cell receptors. --- Neurosciences --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Proteins . --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Proteids --- Polypeptides --- Proteomics --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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The cloning of two G protein-coupled cannabinoid receptors, termed CB1 and CB2, in the early 1990s has stimulated and facilitated research conducted on the physiological function of cannabinoid actions in the brain and throughout the body. In the twenty years since the identification of these two receptors, endogenous ligands (endocannabinoids) for these receptors have been identified, their biosynthetic and metabolic pathways have been discerned, and their functional and regulatory action for signalling through CB1 and CB2 receptors have been described. More recently, it has become has become evident that cannabinoids exert actions at non-CB1, non-CB2 receptors. Much less is understood about these actions. Many of these novel “targets” are in the process of being characterized functionally and physiologically, and the therapeutic value of targeting these non-CB1, non-CB2 receptors is being evaluated. The purpose of this volume is to present the current knowledge on the atypical actions of cannabinoids on these new targets. This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.
Cannabinoids -- Receptors. --- Medicine. --- Receptors, Cannabinoid. --- Cannabinoids --- Hormones --- Receptors, G-Protein-Coupled --- Biological Science Disciplines --- Terpenes --- Neurotransmitter Agents --- Receptors, Cell Surface --- Natural Science Disciplines --- Molecular Mechanisms of Pharmacological Action --- Hydrocarbons --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Physiological Effects of Drugs --- Disciplines and Occupations --- Membrane Proteins --- Pharmacologic Actions --- Organic Chemicals --- Proteins --- Chemical Actions and Uses --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Pharmacology --- Receptors, Cannabinoid --- Endocannabinoids --- Medicine --- Health & Biological Sciences --- Neurology --- Therapeutic use --- Physiological effect. --- Receptors. --- Human physiology. --- Neurosciences. --- Pharmacology. --- Proteins. --- Animal physiology. --- Biomedicine. --- Human Physiology. --- Animal Physiology. --- Pharmacology/Toxicology. --- Cannabis --- Hallucinogenic drugs --- Cell receptors. --- Toxicology. --- Chemicals --- Poisoning --- Poisons --- Animal physiology --- Animals --- Biology --- Anatomy --- Human biology --- Medical sciences --- Physiology --- Human body --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Toxicology --- Proteins . --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Physiological effect
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Marijuana --- Cannabis. --- Cannabinoids. --- Medical Marijuana. --- Therapeutic use. --- Marijuana Dispensaries --- Marijuana Treatment --- Medical Cannabis --- Medicinal Cannabis --- Medicinal Marijuana --- Cannabis, Medical --- Cannabis, Medicinal --- Dispensaries, Marijuana --- Marijuana, Medical --- Marijuana, Medicinal --- Treatment, Marijuana --- Cannabis --- Receptors, Cannabinoid --- Cannabinoid Receptor Agonists --- Cannabis indica --- Cannabis sativa --- Hemp Plant --- Marihuana --- Bhang --- Ganja --- Hashish --- Hemp --- Bhangs --- Cannabi --- Ganjas --- Hashishs --- Hemp Plants --- Hemps --- Plant, Hemp --- Plants, Hemp --- Medical Marijuana --- Hallucinogenic drugs --- Terpenes --- Cannabis gigantea --- Gallow grass --- Cannabaceae --- Medical marijuana --- Cannabinoid --- pharmacology --- general medicine --- public heath --- Cannabinoids --- Therapeutic use --- Weed (Marijuana)
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The past two decades have seen a tremendous growth in knowledge related to cannabinoid receptor signaling in brain. In addition, the impact and consequences of cannabinoid modulation of monoaminergic circuits is steadily emerging demonstrating a significant interaction between these two systems in a variety of psychiatric (affective disorders) and neurological disorders (multiple sclerosis, pain). Despite increasing evidence from preclinical data suggesting that therapeutic use of cannabinoid-based drugs may outweigh any potential risks in certain serious medical conditions, the debate surrounding its widespread utility continues as regulatory concerns preclude a smooth transition of promising preclinical studies into clinical trial testing. This may persist in the near future as state and federal governments debate over regulation of medicinal applications of cannabis. Applications for medicinal cannabinoids that are already under investigation include the treatment of nausea, anorexia, neurodegeneration, inflammation, excitotoxicity and pain. The appetitive and anti-emetic properties of cannabinoids have led to the approval of their use in chemotherapy and AIDS patients. There is growing evidence for therapeutic cannabinoid effects on inflammatory and excitotoxic cellular processes that are linked to epilepsy, Parkinson’s disease, amyotrophic lateral sclerosis, spasticity, and central nervous system injury. The chapters, herein, review and discuss current insights into the brain endocannabinoid system, cannabinoid receptor signaling on synaptic plasticity, potential therapeutic applications with a particular focus on endocannabinoid modulation of dopaminergic, noradrenergic and serotonergic circuitry. The potential for establishing cannabinoid-monoaminergic interactions as a novel target in the development of improved treatment strategies for psychiatric and neurological disorders is promising and will require future clinical studies to determine whether promising pre-clinical findings translate into new therapies.
Cannabinoids -- Therapeutic use. --- Medicine. --- Mental illness -- Treatment. --- Nervous system -- Diseases -- Treatment. --- Neurochemistry. --- Neurology. --- Neurosciences. --- Psychiatry. --- Cannabinoids --- Cannabis --- Diseases --- Receptors, G-Protein-Coupled --- Psychiatry and Psychology --- Therapeutics --- Neurotransmitter Agents --- Receptors, Cell Surface --- Molecular Mechanisms of Pharmacological Action --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacologic Actions --- Membrane Proteins --- Chemical Actions and Uses --- Proteins --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Mental Disorders --- Drug Therapy --- Endocannabinoids --- Nervous System Diseases --- Receptors, Cannabinoid --- Medicine --- Health & Biological Sciences --- Neurology --- Therapeutic use --- Psychopharmacology. --- Nervous system --- Therapeutic use. --- Treatment. --- Behavioral pharmacology --- Drugs --- Psychotropic effects --- Biomedicine. --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Hallucinogenic drugs --- Terpenes --- Biochemistry --- Neurosciences --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Neurology .
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There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoid system and potential strategies for targeting this system in the clinic.
Receptors, Cannabinoid --- Endocannabinoids --- Receptors, G-Protein-Coupled --- Neurotransmitter Agents --- Hormones --- Molecular Mechanisms of Pharmacological Action --- Receptors, Cell Surface --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Membrane Proteins --- Pharmacologic Actions --- Physiological Effects of Drugs --- Chemical Actions and Uses --- Proteins --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Cannabinoids --- Pharmacology, Experimental. --- Physiological effect. --- Experimental pharmacology --- Medicine. --- Immunology. --- Neurosciences. --- Pharmacology. --- Psychopharmacology. --- Cytokines. --- Growth factors. --- Cell biology. --- Biomedicine. --- Pharmacology/Toxicology. --- Cell Biology. --- Cytokines and Growth Factors. --- Therapeutics, Experimental --- Cannabis --- Hallucinogenic drugs --- Terpenes --- Toxicology. --- Cytology. --- Immunobiology --- Life sciences --- Serology --- Behavioral pharmacology --- Drugs --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Chemicals --- Medicine --- Poisoning --- Poisons --- Cellular immunity --- Immune response --- Psychotropic effects --- Toxicology --- Regulation --- Cell growth factors --- Cellular growth factors --- Growth peptides --- Growth promoting substances --- Growth substances --- Peptide growth factors --- Peptide regulatory factors --- Polypeptide growth factors --- Cytokines --- Peptides --- Drug effects --- Medical pharmacology --- Pharmacy --- Physiological effect
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