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Endosymbiosis is a primary force in eukaryotic cell evolution. In order to understand the molecular mechanisms involved in this mutualistic relationship, experiments to reproduce endosymbiosis are indispensable. The ciliate "Paramecium" is an ideal host for performing such studies. Topics presented in this volume are: the origins of algal and bacterial symbionts in "Paramecium", the diversity of endosymbiotic bacteria, such as "Holospora" bacteria and especially "Chlorella" species, as well as the infection and maintenance processes. The metabolic control, the regulation of circadian rhythms and photobiological aspects of the mutualistic association, as well as the killer effect of "Paramecium" and its causative agents are further points discussed.

Chlorella. --- Endosymbiosis. --- Host-bacteria relationships. --- Paramecium. --- Paramecium --- Endosymbiosis --- Chlorella --- Host-bacteria relationships --- Chlorophyta --- Alphaproteobacteria --- Classification --- Biological Processes --- Biological Evolution --- Genetic Phenomena --- Microbial Interactions --- Peniculina --- Viridiplantae --- Biological Phenomena --- Phenomena and Processes --- Information Science --- Microbiological Processes --- Proteobacteria --- Hymenostomatida --- Bacteria --- Oligohymenophorea --- Microbiological Phenomena --- Plants --- Ciliophora --- Organisms --- Eukaryota --- Alveolata --- Phylogeny --- Symbiosis --- Holosporaceae --- Earth & Environmental Sciences --- Zoology --- Health & Biological Sciences --- Ecology --- Invertebrates & Protozoa --- Cytology. --- Paramaecium --- Endosymbiotic relationships --- Life sciences. --- Cell biology. --- Microbiology. --- Life Sciences. --- Cell Biology. --- Parameciidae --- Bacteria-host relationships --- Relationships, Host-bacteria --- Host-parasite relationships --- Chlorellaceae

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There is currently increasing interest concerning the biology and disease caused by Acinetobacter species. Such interest, however, developed relatively slowly because of the necessity to clarify the confusing taxonomy of these organisms. Much work was needed to identify various species as members of this genus, to recognize their epidemiologic profile, their pathogenic role and their increasing importance as multi-antibiotic resistant organisms. In recent years improvement of genetic approaches, recognition of plasmids, integrons and chromosomal sources of resistance mechanisms aroused interest on the role of Acinetobacters in disease by many microbiologists and clinicians, especially internists and infectious disease specialists. In this regard, physicians are frequently confronted with extremely difficult therapeutic approaches for treatment and prevention of severe nosocomial infections due to multi antibiotic resistant Acinetobacter. Moreover, recent observations of community acquired infections have been reported, especially in patients with various risk factors such as immuno-deficiencies. Also, it is now becoming evident that Acinetobacter infections occur frequently in violent situations such as earthquake or war zones. The mechanisms of Acinetobacter virulence are becoming increasingly clear, providing new insights into their pathogenic role in community acquired infections. It is apparent the time is appropriate for detailed review of the increasing knowledge concerning important new information, both clinical and therapeutic, especially information concerning virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are accumulating in almost an exponential manner since publication of previous books on this subject in 1991 and 1996.

Life Sciences. --- Microbiology. --- Immunology. --- Virology. --- Life sciences. --- Medical virology. --- Sciences de la vie --- Immunologie --- Virologie médicale --- Microbiologie --- Acinetobacter infections. --- Acinetobacter. --- Nosocomial infections. --- Acinetobacter infections --- Acinetobacter --- Nosocomial infections --- Moraxellaceae Infections --- Biology --- Moraxellaceae --- Infection --- Anti-Infective Agents --- Therapeutic Uses --- Gram-Negative Aerobic Rods and Cocci --- Gram-Negative Bacterial Infections --- Bacterial Infections and Mycoses --- Biological Science Disciplines --- Gammaproteobacteria --- Gram-Negative Aerobic Bacteria --- Bacterial Infections --- Natural Science Disciplines --- Diseases --- Proteobacteria --- Pharmacologic Actions --- Disciplines and Occupations --- Bacteria --- Gram-Negative Bacteria --- Chemical Actions and Uses --- Chemicals and Drugs --- Organisms --- Acinetobacter Infections --- Microbiology --- Anti-Bacterial Agents --- Cross Infection --- Health & Biological Sciences --- Microbiology & Immunology --- Hospital-acquired infections --- Hospital infections --- Acinetobacter diseases --- Colloides --- Herella --- Mimae --- Iatrogenic diseases --- Gram-negative bacterial infections --- Neisseriaceae

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Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. Coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. Coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. Coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.

Escherichia coli. --- Systems biology. --- Escherichia coli --- Systems biology --- Systems Biology --- Escherichia --- Computational Biology --- Biology --- Enterobacteriaceae --- Biological Science Disciplines --- Gram-Negative Facultatively Anaerobic Rods --- Gammaproteobacteria --- Natural Science Disciplines --- Proteobacteria --- Gram-Negative Bacteria --- Bacteria --- Disciplines and Occupations --- Organisms --- Biochemistry --- Biology - General --- Microbiology & Immunology --- Chemistry --- Health & Biological Sciences --- Physical Sciences & Mathematics --- Biochemistry. --- Biotechnology. --- Life sciences. --- Microbial genetics. --- Microorganisms --- Biosciences --- Sciences, Life --- Biological chemistry --- Chemical composition of organisms --- Physiological chemistry --- E. coli (Bacterium) --- Genetics --- Composition --- Microbiology. --- Microbial genomics. --- Life Sciences. --- Biochemistry, general. --- Microbial Genetics and Genomics. --- Applied Microbiology. --- Microbiology --- Science --- Chemical engineering --- Genetic engineering --- Medical sciences --- Genomics --- Microbial genetics --- Microbial biology

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Rheumatoid Arthritis and Proteus explores the idea that Rheumatoid arthritis is caused by a urinary tract infection as a result of Proteus bacteria. Rheumatoid arthritis is a severe, painful and crippling disease affecting millions of people throughout the world, especially women. Genetic studies over the last 30 years have shown that individuals who possess the white cell blood groups HLA-DR1/4 carry a susceptibility sequence and are more likely to develop the disease.   This book uses the methods of Sir Karl Popper, the philosopher of science, to present 12 “Popper sequences” which have been identified to indicate that Proteus is the causative agent of Rheumatoid Arthritis. Rheumatoid Arthritis and Proteus proposes that Anti-Proteus therapies should be followed as early as possible to prevent the crippling and irreversible joint deformities that occur in Rheumatoid Arthritis.

Proteus (Bacteria). --- Rheumatoid arthritis. --- Rheumatoid arthritis --- Proteus (Bacteria) --- Biology --- Enterobacteriaceae --- Autoimmune Diseases --- Rheumatic Diseases --- Arthritis --- Enterobacteriaceae Infections --- Biological Science Disciplines --- Immune System Diseases --- Musculoskeletal Diseases --- Connective Tissue Diseases --- Gram-Negative Facultatively Anaerobic Rods --- Gammaproteobacteria --- Gram-Negative Bacterial Infections --- Joint Diseases --- Proteobacteria --- Natural Science Disciplines --- Diseases --- Bacterial Infections --- Skin and Connective Tissue Diseases --- Gram-Negative Bacteria --- Disciplines and Occupations --- Bacteria --- Bacterial Infections and Mycoses --- Organisms --- Arthritis, Rheumatoid --- Microbiology --- Proteus Infections --- Proteus --- Medicine --- Health & Biological Sciences --- Musculoskeletal System Diseases --- Etiology. --- Liquidobacterium --- Adjuvant arthritis --- Arthritis deformans --- Arthrosis deformans --- Rheumatic gout --- Medicine. --- Rheumatology. --- Medicine & Public Health. --- Autoimmune diseases --- Blood hyperviscosity syndrome --- Rheumatism --- Internal medicine --- Connective tissues --- Joints

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Proceedings of the FEMS Symposium on Genes and Proteins Underlying Microbial Urinary Tract Virulence: Basic Aspects and Applications, held September 16-19, 1999, in Pécs, Hungary. Urinary tract infections are among the most frequent diseases caused by microbial pathogens. In this volume, researchers, clinical microbiologists and clinicians exchange the latest ideas covering four major aspects of this important topic: Genetic information, synthesis and assembly of virulence factors in urinary pathogens; Regulation of genes involved in the phenotypic appearance of virulence; Host-parasite interactions determining the process and outcome of the infection; Possible applications of the above aspects in diagnosis, therapy and prevention.

Escherichia coli infections -- Congresses. --- Urinary tract infections -- Congresses. --- Virulence (Microbiology) -- Molecular aspects -- Congresses. --- Urinary tract infections --- Virulence (Microbiology) --- Escherichia coli infections --- Urinary Tract Infections --- Enterobacteriaceae --- Virulence --- Gram-Negative Facultatively Anaerobic Rods --- Gammaproteobacteria --- Proteobacteria --- Medicine. --- Pharmacology. --- Infectious diseases. --- Nephrology. --- Urology. --- Epidemiology. --- Medicine & Public Health. --- Infectious Diseases. --- Pharmacology/Toxicology. --- Molecular aspects --- Congresses --- Emerging infectious diseases. --- Toxicology. --- Genetic aspects --- Internal medicine --- Kidneys --- Diseases --- Public health --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Medicine --- Genitourinary organs --- Physiological effect --- Urinary organs --- Communicable diseases --- Infection --- Microbial virulence --- Pathogenic microorganisms --- Colibacillosis --- Gram-negative bacterial infections --- Infections