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This book provides unique insights into how health professionals and people with Parkinson's disease shape care together. It shows both the courage and vulnerabilities of those who have to face this disease. It consists of photos of people with Parkinson's disease and their care professionals, both of their interaction and portrayed individually, interwoven with fragments of their dialogue about meaningful care. This book is an integral part of a research project at Radboud university medical center into person-centred care. With it, we hope to contribute to a positive, hopeful vision of ever-improving Parkinson's care.
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Parkinson’s disease is an increasingly common neurodegenerative condition, which causes not only dysfunction of movement but also a broad range of nonmotor features, including mood disturbance, sleep dysfunction, autonomic dysfunction, cognitive deficits, and dementia, and neuropsychiatric symptoms. A major conundrum in this condition is understanding its striking clinical variability, which encompasses a spectrum from a benign phenotype with levodopa responsive symptoms and minimal progression, to a malignant phenotype with rapid progression to severe gait dysfunction, falls and dementia. This book integrates the considerable expertise of a range of authors from different disciplines, from clinicians through to basic scientists, to present a comprehensive and up-to-date overview of Parkinson’s disease. In recent years, we have made significant progress in understanding the pathological and genetic basis of Parkinson’s disease and its heterogeneous forms, and the first section of the book is dedicated to reviewing this. The variable clinical features of Parkinson’s disease and its differential diagnosis are then considered. The final section provides a detailed overview of treatment approaches, including not only pharmacological therapies but also surgical therapies including deep brain stimulation and cell transplantation strategies. The combination of basic biology, clinical knowledge and therapeutics gives this book a very broad appeal. It will be of value to clinicians and health professionals caring for patients with Parkinson’s disease, as well as providing an excellent introduction for junior researchers entering the field.
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« Historique, symptômes, épidémiologie, moyens diagnostiques, traitement médical et chirurgical, rééducation, adaptation à la vie de tous les jours, rôle des aidants ... Le docteur Chantal Hausser-Hauw passe en revue, de façon simple et claire, les différentes facettes de la maladie de Parkinson, exposant les hypothèses qui permettent d'en expliquer l'origine, en particulier le rôle capital de l'alpha-synucléine. Quelles sont les perspectives de traitement et de prévention? Quelles autres voies, notamment la thérapie par la lumière ou la thérapie génique, la recherche clinique et fondamentale innovante ouvre-t-elle? Autant de questions auxquelles les proches et les malades trouveront enfin des réponses précises, à jour des dernières avancées scientifiques. »--Quatrième de couverture.
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Bien connue pour ses aspects moteurs, la maladie de Parkinson ne possède à ce jour aucun traitement curatif. Après quelques années, la maladie se complique par l'apparition de symptômes non moteurs, de fluctuations de réponse et d'une plus grande sensibilité aux effets secondaires des médications spécifiques. À ce stade, peuvent également apparaitre des fluctuations de la mobilité, des dyskinésies (mouvements involontaires), des symptômes axiaux (dysarthrie, dysphagie, troubles de l'équilibre et/ou sphinctériens, etc.) ainsi que des complications des systèmes digestif, urologique, rhumatologique, psychique, neurovégétatif, etc.Ces diverses complications engendrent un fardeau de plus en plus pénible à supporter pour le patient et ses proches. Une situation qui ne peut qu'interpeller les soignants et expliquer aisément la nécessité d'une prise en charge individuelle, globale et multidisciplinaire. Sans oublier les aspects d'éducation thérapeutique. Abordant de manière détaillée les différents angles de la maladie de Parkinson et les affections apparentées, Traiter le Parkinson relate l'expérience acquise par une structure spécialisée aux plans médical et paramédical, sans en oublier les aspects humains et de service.Cette nouvelle édition mise à jour est destinée à toutes les professions concernées par la maladie de Parkinson : médecins, infirmières, kinésithérapeutes, logopèdes, ergothérapeutes, nutritionnistes, psychologues, assistants sociaux, pharmaciens, etc. Il intéressera également les patients et leur entourage, par les nombreux trucs et astuces permettant d'améliorer le quotidien.
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An estimated 50% to 80% of individuals with Parkinson's disease experience Parkinson's disease dementia (PDD). Based on the prevalence and clinical complexity of PDD, this book provides an in-depth update on topics including epidemiology, diagnosis, and treatment. Chapters discuss non-medical therapies and examine views on end-of-life issues as well. This book is a must-read for anyone interested in PDD whether they are a patient, caregiver, or doctor.
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The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Florence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus.
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This guideline covers diagnosing and managing Parkinson's disease in people aged 18 and over. It aims to improve care from the time of diagnosis, including monitoring and managing symptoms, providing information and support, and palliative care.
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