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Driven by ground-based, airborne, and IRAS observations, the PAH hypothesis was first formulated in the mid-eighties : the widespreas emission features in the 3-13 æm range are due to UV-pumped, IR fluorescence by large Polycyclic Aromatic Hydrocarbon molecules. These molecules are a ubiquitous component of the interstellar medium both in local galaxies as well as out to redshifts of ̃3 and probably beyond, play an important role in its physical and chemical characteristics, and form a key link between small hydrocarbon species and large carbonaceous grains. This book gathers contributions that reflect the evolution of the field over the last 25 years, taking advantage of IR space missions - ISO, Spitzer and AKARI - and of dedicated experimental and quantum-chemical studies. We have now reached a stage where we can develop these mid-infrared features as diagnostic tools to study star formation processes, protoplanetary disks as well as galaxy assemblage in the early Universe. The current Herschel/Planck area opens the possibility to better characterize the mid-IR carriers through their contribution to the far-IR and mm emissions. Still, much effort is required before we will fully understand the formation and nature of interstellar PAHs and their role in the Universe. Physical chemists can play an important role in driving this field. This book aims at discussing the state-of-the-art of the PAH hypothesis and to chart the future in this interdisciplinary field. It highlights the various aspects of interstellar PAHs:- Rich IR spectra of interstellar PAHs- PAHs and star formation in the near and far Universe- The lifecycle of PAHs in space- PAHs in regions of planet formation- PAHs and carbonaceous grains & Solar system materials.
Stars --- Organic Chemistry, --- Infrared spectra --- Polycyclic aromatic hydrocarbons --- Congresses. --- Congresses. --- Congresses. --- PAH hypothesis --- space missions
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Indonesia
Political anthropology --- Timor (Indonesian people) --- #SBIB:39A11 --- #SBIB:39A75 --- Ambeno (Southeast Asian people) --- Ambenu (Southeast Asian people) --- Atoin Meto (Southeast Asian people) --- Atoin Pah Meto (Southeast Asian people) --- Atoni --- Atoni (Indonesian people) --- Atoni Ambeno (Southeast Asian people) --- Atoni Meto (Southeast Asian people) --- Atoni Pa Meto (Southeast Asian people) --- Atoni Pah Meto (Southeast Asian people) --- Baikeno (Southeast Asian people) --- Baikenu (Southeast Asian people) --- Bikenu (Southeast Asian people) --- Biqueno (Southeast Asian people) --- Kupangese (Southeast Asian people) --- Lais Meto (Southeast Asian people) --- Meto (Southeast Asian people) --- Molok Meto (Southeast Asian people) --- Oe Cusi (Southeast Asian people) --- Oecusse (Southeast Asian people) --- Oecussi (Southeast Asian people) --- Oekusi (Southeast Asian people) --- Orang Gunung (Southeast Asian people) --- Orang Timor Asli (Southeast Asian people) --- Pah Meto (Southeast Asian people) --- Timol (Southeast Asian people) --- Timor (Southeast Asian people) --- Timoreesch (Southeast Asian people) --- Timoreezen (Southeast Asian people) --- Timorese (Southeast Asian people) --- Uab Atoni (Southeast Asian people) --- Uab Atoni Pah Meto (Southeast Asian people) --- Uab Meto (Southeast Asian people) --- Uab Pah Meto (Southeast Asian people) --- Vaikenu (Southeast Asian people) --- Vaikino (Southeast Asian people) --- Ethnology --- Anthropology, Political --- Government, Primitive --- Political science --- Antropologie : socio-politieke structuren en relaties --- Etnografie: Azië --- Anthropological aspects --- Atoni (Southeast Asian people) --- Timorais --- Atoni (Southeast Asian people). --- Political anthropology. --- Timor (Indonesian people). --- Asia --- Asian and Pacific Council countries --- Eastern Hemisphere --- Eurasia --- indonesia --- Kupang --- Liurai --- Principality --- Rice --- Timor
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Millions of people are today forced to flee their homes as a result of conflict, systematic discrimination, or other forms of persecution. The core instruments on which they must rely to secure international protection are the 1951 Convention Relating to the Status of Refugees and its 1967 Protocol. This book examines key challenges that the Convention faces, including the scope of the principle of non-refoulement and the proper application of the elements of the refugee definition. The Office of the United Nations High Commissioner for Refugees (UNHCR) commissioned papers on these issues from some of the world's pre-eminent international refugee lawyers, discussed at a series of expert roundtable meetings during 2001 as part of UNHCR's Global Consultations on International Protection. The papers and roundtable conclusions are published here, together with an introduction and the landmark declaration of the 2001 Ministerial Meeting of States Parties to the Convention and/or Protocol.
Refugees --- Displaced persons --- Persons --- Aliens --- Deportees --- Exiles --- Legal status, laws, etc. --- Convention Relating to the Status of Refugees --- Da Panāh Ghūṣhtūnko da Waz̤ʻe pah Aṛah Muqāwalah (Kunwānsiyūn) --- Konvensi Mengenai Kedudukan Pengungsi --- Kunvānsiyūn-i 1951 dar Umūr-i Panāhindahʹgān --- Refugee Convention --- United Nations Refugee Convention --- Legal status, laws, etc --- Réfugiés --- Droit --- Congresses. --- Law --- General and Others
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Ronald Holt recounts the survival of a people against all odds. A compound of rapid white settlement of the most productive Southern Paiute homelands, especially their farmlands near tributaries of the Colorado River; conversion by and labor for the Mormon settlers; and government neglect placed the Utah Paiutes in a state of dependency that ironically culminated in the 1957 termination of their status as federally recognized Indians. That recognition and attendant services were not restored until 1980, in an act that revived the Paiutes' identity, self-government, land ownership, and sense of
Mormons -- History -- Sources. --- Mormons -- Social conditions. --- Paiute Indians -- Government relations. --- Paiute Indians -- History -- Sources. --- Paiute Indians -- Social conditions. --- Paiute Indians --- Mormons --- Gender & Ethnic Studies --- Social Sciences --- Ethnic & Race Studies --- History --- Government relations --- Social conditions --- Government relations. --- Social conditions. --- Latter-Day Saints --- Pah-Ute Indians --- Piute Indians --- Mormon Church --- Indians of North America --- Numic Indians --- Christians --- Latter Day Saints --- Brighamite Mormons --- Church of Christ (Temple Lot) members --- Church of Jesus Christ of Latter-day Saints members --- Church of Jesus Christ (Strangites) members --- Hedrikites --- Josephite Mormons --- Reorganized Church of Jesus Christ of Latter Day Saints members --- Reorganized Mormons --- RLDS Mormons --- Strangite Mormons --- Temple Lot Mormons --- Utah Mormons
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Food safety and quality represent a major concern worldwide, not only for the potential risk to consumers’ health but also for the economic losses occurring in food industries. A complete quality system involves raw matter, environmental conditions, production processes, storage and distribution, taking into account the purpose for which the end product is intended. Appropriate analytical methods combined with good hygiene practices are essential to ensure a safe food supply and/or to minimize the occurrence of foodborne outbreaks due to the consumption of food contaminated with pathogens such as bacteria, fungi and parasites. On the other hand, the lack of measures able to detect quality deterioration, spoilage, authenticity and adulteration, as well as texture, rheology and sensory properties of food can affect the food industry economy and reduce consumer confidence. The use of rapid analytical methods can benefit food companies in saving time and cost, indicating the importance of developing new reliable assays for good and fast control of products throughout the whole food chain.
Research & information: general --- Biology, life sciences --- Food & society --- honey --- water activity --- moisture content --- regression --- categorical testing --- QuEChERS --- dispersive liquid–liquid microextraction --- sulfuric acid treatment --- gas chromatography --- tandem mass spectrometry --- priority substances --- fish samples --- Trichinella spp. --- slaughterhouse --- accreditation --- proficiency testing --- PAH content --- Hercegovačka pečenica --- traditional smoking --- industrial smoking --- Listeria monocytogenes --- outbreak --- molecular methods --- real-time PCR --- screening --- Anisakis spp. --- LAMP --- validation --- anisakidae family --- NIR --- PLS --- PCA --- correlogram --- sensory analysis --- gold nanoparticles --- histamine --- UV-visible and fluorescence --- visual detection --- spoilage marker --- safety --- assay --- pollutants --- polyciclic aromatic hydrocarbons --- Trichinella --- Anisakis --- nanoparticles
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Pulmonary arterial hypertension is a severe and progressive disorder affecting the blood vessels in the lungs. Typically, symptoms first appear at around 30–40 years of age and, without treatment, can lead to fatal heart disease within a few years. Genetic studies over the past decade have identified numerous genes that contribute to disease progression but, for many sufferers, the underlying genetic cause remains elusive. The collection of reviews and original research articles contained within this book provide an overview of recent advancements in understanding the genetic risk factors for pulmonary arterial hypertension. We further examine the emerging interplay between genetic variants and clinical outcomes, providing a framework for new treatments and improved patient care.
Research & information: general --- Biology, life sciences --- Genetics (non-medical) --- pulmonary arterial hypertension --- massive parallel sequencing --- NGS --- digenic inheritance --- and genetics --- BMPR2 promoter --- pathogenic variant --- heritable pulmonary arterial hypertension --- genetic analysis --- NGS gene panel --- BMPR2 --- TBX4 --- GDF2 --- EIF2AK4 --- genomics --- pediatrics --- lung disease --- endothelial cells --- smooth muscle cells --- DNA damage --- DNA repair --- expression quantitative trait locus --- eQTL --- blood --- genetics --- exome sequencing --- molecular genetics --- paediatrics --- bone morphogenetic protein receptor type 2 --- heritable --- familial --- estrogen --- estradiol --- penetrance --- gender --- PAH --- forward phenotyping --- forward genetics --- reverse genetics --- reverse phenotyping --- intermediate phenotypes --- whole-genome sequencing --- epigenetic inheritance --- genetic heterogeneity --- phenotypic heterogeneity --- pulmonary hypertension --- bone morphogenetic protein receptor 2 --- signaling --- repurposed drugs --- pharmaceuticals --- miRNA --- clinical trials --- n/a
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Migration. Refugees --- Human rights --- International private law --- Refugees --- Réfugiés --- Legal status, laws, etc. --- Droit --- 341.244 --- 341.43 --- Uitvoering van verdragen. Ratificatie van verdragen. Treaty-making power. Self-executing treaties --- Uitwijzing. Politieke vluchtelingen. Asielrecht. Vluchtelingenrecht --- 341.43 Uitwijzing. Politieke vluchtelingen. Asielrecht. Vluchtelingenrecht --- 341.244 Uitvoering van verdragen. Ratificatie van verdragen. Treaty-making power. Self-executing treaties --- Réfugiés --- Legal status, laws, etc --- Convention Relating to the Status of Refugees --- Da Panāh Ghūṣhtūnko da Waz̤ʻe pah Aṛah Muqāwalah (Kunwānsiyūn) --- Konvensi Mengenai Kedudukan Pengungsi --- Kunvānsiyūn-i 1951 dar Umūr-i Panāhindahʹgān --- Refugee Convention --- United Nations Refugee Convention --- Refugees - Legal status, laws, etc.
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This collection brings together for the first time more than 360 of Mark Twain's short works written between 1851, the year of his first extant sketch, and 1871, when he renounced his ties with the Buffalo Express and the Galaxy, resolving to ";write but little for periodicals hereafter."; In October 1871 Clemens and his family moved to Hartford, where they would live until 1891. No longer a journalist, he was about to complete his second full-length book, Roughing It. The literary apprenticeship that he had begun twenty years before in the print shops of Hannibal, and pursued in the newspaper offices of Virginia City, San Francisco, and Buffalo, had at last come to a close. The selections included in these volumes represent a generous sampling from Mark Twain's most imaginative journalism, a few set speeches, a few poems, and hundreds of tales and sketches recovered from more than fifty newspapers and journals, as well as two dozen unpublished items of various description-the main body of what can now be found of his early literary and subliterary work, though by no means everything written during those twenty years of experimentation. The selections are ordered chronologically and therefore provide a nearly continuous record of the author's literary activity from his earliest juvenilia up through the mature work that he published in the Galaxy, the Buffalo Express, and many other journals.
LITERARY CRITICISM / American / General. --- Twain, Mark, --- Twain, Mark --- Tvėn, Mark --- Tuėĭn, Mark --- Tuwayn, Mārk --- Twayn, Mārk --- Tʻu-wen, Ma-kʻo --- Tven, M. --- Touen, Makū --- Twain, Marek --- Make Tuwen --- Tuwen, Make --- Make Teviin --- Твен, Марк --- Touain, Mark --- טבןַ, מרק, --- טוויין, מארק, --- טוויין, מרק, --- טווין, מארק, --- טווין, מרק, --- טווען, מארק, --- טוין, מרק, --- טװען, מארק, --- טװײן, מארק, --- 馬克吐温, --- Tuvāyn, Mārk --- Tvāyn, Mārk --- تواين، مارک --- Clemens, Samuel Langhorne --- Snodgrass, Quintus Curtius --- Conte, Louis de --- a duel prevented. --- advice to the unreliable on church going. --- american authors. --- american literature. --- an apology repudiated. --- buffalo express. --- carson city. --- classics. --- connubial bliss. --- dog controversy. --- galaxy. --- gallant fireman. --- hannibal. --- how to cure a cold. --- humor. --- journalism. --- juvenilia. --- literary criticism. --- mark twain. --- more ghosts. --- nevada. --- our stock remarks. --- pah utes. --- poems. --- religion. --- samuel clemens. --- satire. --- short fiction. --- short stories. --- social commentary. --- spanish mine. --- speeches. --- those blasted children.
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This book covedered high-quality contributions (original research articles or review papers) providing a picture on innovations in microbial fermentative processes, including improvements of quality/safety of fermented foods and beverages, production of high added-values products, and valorization/recovery of agro-food wastes.
Technology: general issues --- Biotechnology --- simultaneous saccharification and cultivation (SSC) --- intensive multiple sequential batch cultivation --- thermotolerant yeast --- Kluyveromyces marxianus --- ethanol production --- smoking with open fire --- PAH --- industrial smoking --- clavulanic acid --- Streptomyces clavuligerus --- cell morphology --- shear stress --- high cell density cultivation (HCDC) --- intensive multiple sequential batch (IMSB) --- cell cultivation --- fed-batch at cell level (FBC) --- S. cerevisiae --- dextrin --- bioreactor --- chain elongation --- carboxylate platform --- medium-chain fatty acids --- carboxylic acids --- mixed culture fermentation --- biocontrol --- Bacillus velezensis --- volatile organic compounds --- vascular wilt pathogens --- GABA --- Indonesian fermented foods --- glutamate decarboxylase --- lactic acid bacteria --- L. plantarum --- feast/famine conditions --- industrial-scale bioreactor --- metabolomics --- metabolic response --- penicillin --- Penicillium chrysogenum --- scale-down --- children --- double fortification --- fermented milk --- iron and zinc --- stunting --- synbiotic --- wine --- HS-SPME-GC/MS --- multivariate statistical analysis --- calibration --- whole-plant corn silage --- bacterial community --- fungal community --- metabolites --- fermentation quality --- aerobic stability --- succession pattern --- fermentation process --- n/a
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Autophagy (“auto-digestion”), a lysosome-dependent process, degrades and turns over damaged or senescent organelles and proteins. Autophagy is a highly regulated process that impacts several vital cellular responses, including inflammation, cell death, energy metabolism, and homeostasis of organelles (mitochondria and others). Although the role of autophagy in the maintenance of tissue homeostasis is well documented, its role during tissue injury and regeneration is still emerging. In this Special Issue on “Autophagy in Tissue Injury and Homeostasis”, we focus on the roles of autophagy in systemic, specific tissue (organs/cells) injury or organ failure associated with sepsis, inflammation, metabolic disorder, toxic chemicals, ischemia-reperfusion injury, hypoxic oxidative stress, tissue fibrosis, trauma, and nutrient starvation. The knowledge gained from the identification and characterization of new molecular mechanisms will shed light on biomedical applications for tissue protection through the modulation of autophagy.
Medicine --- aging --- dietary restriction --- acute kidney injury --- mitochondria --- autophagy --- mitophagy --- ischemia --- renal tubular cells --- diabetic nephropathy --- exosomes --- mTOR --- innate immunity --- immune cell --- inflammasome --- Paneth cell --- inflammatory bowel disease --- Crohn’s disease --- hepatocytes --- hepatic stellate cells --- sinusoidal endothelial cells --- macrophages --- fibrosis --- cirrhosis --- hepatocellular carcinoma --- biomarkers --- cell death --- glutaminase --- metabolism --- molecular rehabilitation. --- kidney diseases --- oxidative stress --- inflammation --- ATGs --- intestinal homeostasis --- inflammatory bowel diseases --- HCC therapy --- Autophagy --- acute lung injury --- idiopathic pulmonary fibrosis --- COPD --- tuberculosis --- PAH --- cystic fibrosis --- Beclin-1 --- cardiac dysfunction --- sepsis --- endotoxemia --- muscle regeneration --- stem cell --- immune --- macrophage --- senescence --- exercise --- caloric restriction --- diabetic retinopathy --- PINK1 --- Notoginsenoside R1 --- ethanol --- LC3 --- apoptosis --- Sertoli cell --- Parkin --- TFEB --- infertility --- AMPK --- FOXO --- MTOR --- parkin --- spinal cord injury --- traumatic brain injury --- autophagic flux --- neuronal cell death --- lysosomal damage --- n/a --- Crohn's disease
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