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Marine Manganese Deposits

Manganese nodules --- Deep-sea manganese nodules --- Manganese ores --- Marine mineral resources --- Marine sediments --- Manganese nodules.

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Manganese mines and mining, Submarine --- Manganese nodules

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The Local Lymph Node Assay: DA (LLNA: DA) is a non-radioactive modification to the LLNA method for identifying potential skin sensitizing test substances and measuring the proliferation of lymphocytes they induce in the auricular lymph nodes. The method, described in mouse (CBA/J strain), is based on measurement of the adenosine triphosphate (ATP) content by bioluminescence as an indicator of this proliferation. A minimum of four animals is used per dose group, with a minimum of three concentrations of the test substance, plus a concurrent negative control group and, if appropriate, a positive control group. The experimental schedule is during 8 days. The time from animal sacrifice to measurement of ATP should not exceed 30 min. The procedure from excision of lymph nodes to ATP measurement should be kept uniform for each animal and completed within 20 minutes. The luciferin/luciferase method is applied to measure the bioluminescence in Relative Luminescence Units (RLU). This study includes: measurements (weighing, RLU), and clinical daily observations. The results are expressed as the Stimulation Index (SI) obtained by calculation. The SI should be ¡Ý1.8 before further evaluation of the test material as a potential skin sensitizer is warranted.

Lymph nodes --- Lymph glands --- Lymph nodules --- Nodes, Lymph --- Nodules, Lymph --- Nodus lymphaticus --- Lymphatics --- Lymph nodes.

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Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases. Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.

Medicine --- Health & Biological Sciences --- Pathology --- Lymph nodes --- Histology, Pathological --- Diseases --- Lymph glands --- Lymph nodules --- Nodes, Lymph --- Nodules, Lymph --- Nodus lymphaticus --- Medicine. --- Oncology. --- Pathology. --- Medicine & Public Health. --- Lymphatics --- Oncology  . --- Tumors --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Botany & plant sciences --- Nitrogen Fixation --- Nodules --- Metabolic Adjustment --- Gene Expression reprogramming --- Omics --- Signal Transduction --- Long-Range Signals --- Legume --- Rhizobia