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Adhesive interactions are important for cell trafficking, differentiation, function and tissue formation. In the nervous system, many cell adhesion molecules (CAMs) are involved in migration of neuroblasts, outgrowth and fasciculation of neuronal processes, formation of synapses and rearrangements of synaptic contacts associated with plasticity including learning and memory. More than eighty CAMs were found to be localized at synaptic sites, where they in a regulated manner bridge pre- and postsynaptic specializations thereby modulating synaptic function. Structure and Function of the Neural Cell Adhesion Molecule NCAM describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM). NCAM is one of the first identified and most studied CAMs, and this book is the first attempt to collectively summarize our current knowledge of this important cell adhesion molecule.
Molecular neurobiology. --- Neurochemistry. --- Neurons -- Physiology. --- Molecular neurobiology --- Neurochemistry --- Neural Cell Adhesion Molecules --- Physiology --- Cell Adhesion Molecules, Neuronal --- Biological Science Disciplines --- Natural Science Disciplines --- Cell Adhesion Molecules --- Antigens, Surface --- Membrane Glycoproteins --- Disciplines and Occupations --- Antigens --- Membrane Proteins --- Glycoproteins --- Proteins --- Biological Factors --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Neurology --- Neuroscience --- Human Anatomy & Physiology --- Medicine --- Health & Biological Sciences --- Cell adhesion molecules. --- Biomolecules. --- Biological molecules --- Adhesion molecules (Cytology) --- Adhesion substances (Cytology) --- Cell adhesion substances --- Intercellular adhesion molecules --- Morphoregulatory molecules --- Medicine. --- Human physiology. --- Neurosciences. --- Neurobiology. --- Biomedicine. --- Human Physiology. --- Neurosciences --- Biochemistry --- Neural sciences --- Neurological sciences --- Medical sciences --- Nervous system --- Human biology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Molecules --- Molecular biology --- Biomolecules --- Desmosomes --- Hemidesmosomes
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The discovery of mirror neurons and of a mirror neuron system in the human brain raises the interesting possibility that "mirroring" may constitute novel instances of mental simulation. It also provides the basis for unique processes such as "mindreading," the ability to make inferences about the actions of others. That an elementary process in motor cognition may be foundational to mindreading goes a long way in providing a rational basis for the study of social cognition. Social cognition is a broad discipline that encompasses many issues not yet adequately addressed by neurobiologists. In Mirror Neuron Systems: The Role of Mirroring Processes in Social Cognition, leading thinkers in this nascent field craft chapters aimed at sparking a dialogue regarding the relevance of mirroring neural systems in cognition. Thought-provoking and cutting-edge, Mirror Neuron Systems: The Role of Mirroring Processes in Social Cognition provides the basis for extended discussion among interested readers and lays down the guidelines for future research in this fascinating and expanding field. It addresses issues common to different perspectives, raises contrary views, and creates the basis for an extended dialogue and discussion.
Cognitive neuroscience. --- Mirror neurons. --- Neurons --Physiology. --- Neurons --- Mirror neurons --- Cognitive neuroscience --- Imitative Behavior --- Social Behavior --- Cognition --- Physiology --- Cells --- Nervous System --- Biological Science Disciplines --- Behavior --- Mental Processes --- Behavior and Behavior Mechanisms --- Natural Science Disciplines --- Anatomy --- Psychological Phenomena and Processes --- Psychiatry and Psychology --- Disciplines and Occupations --- Neuroscience --- Neurology --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Cognitive neuropsychology --- Psychology. --- Neurosciences. --- Neurology. --- Neurobiology. --- Neuropsychology. --- Cognitive psychology. --- Cognitive Psychology. --- Cognitive science --- Neuropsychology --- Consciousness. --- Psychology, clinical. --- Neurosciences --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Medical sciences --- Apperception --- Mind and body --- Perception --- Philosophy --- Psychology --- Spirit --- Self --- Diseases --- Neurology . --- Neurophysiology --- Psychophysiology --- Psychology, Cognitive
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This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. Deciphering these adaptations is essential to comprehending how living organisms develop. The aim of this book is to review the best-known modifications and adaptations of the cell cycle during development. The first chapters cover the general problems of how the cell cycle evolves, while consecutive chapters guide readers through the plethora of such phenomena. The book closes with a description of specific changes in the cell cycle of neurons in the senescent human brain. Taken together, the chapters present a panorama of species - from worms to humans - and of developmental stages - from unfertilized oocyte to aged adult.
Cell cycle -- Physiology. --- Cell cycle. --- Developmental biology. --- Embryology -- Physiology. --- Evolution (Biology). --- Neurons -- Physiology. --- Cell cycle --- Embryology --- Neurons --- Cells --- Embryonic and Fetal Development --- Biological Science Disciplines --- Cell Physiological Processes --- Nervous System --- Anatomy --- Cell Physiological Phenomena --- Natural Science Disciplines --- Reproduction --- Morphogenesis --- Growth and Development --- Phenomena and Processes --- Disciplines and Occupations --- Reproductive Physiological Processes --- Reproductive Physiological Phenomena --- Physiological Processes --- Physiological Phenomena --- Reproductive and Urinary Physiological Phenomena --- Cell Cycle --- Embryonic Development --- Physiology --- Biology --- Health & Biological Sciences --- Cytology --- Biophysics --- Mitotic cycle --- Nuclear cycle (Cytology) --- Life sciences. --- Cell biology. --- Life Sciences. --- Developmental Biology. --- Cell Biology. --- Biological rhythms --- Cytology. --- Cell biology --- Cellular biology --- Cytologists --- Development (Biology) --- Growth --- Ontogeny
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Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions. This volume covers two main aspects of research into sex differences in psychopharmacology: preclinical research, and clinical work in this area. The first part of the volume deals with the preclinical research, and explains how male and female animals differ in their sexual behaviour, drug dependence, cognition, genetics and stress reactivity, with an introductory chapter explaining basic mechanisms of sex steroid action in the body and brain. The second part focuses on the importance of improved understanding of sex differences in our approach to the treatment of psychiatric illness. This includes illnesses such as autism, anorexia, depression, schizophrenia, and bipolar disorder. This volume will be of considerable interest to mental health professionals, including psychiatrists , nurses , allied health clinicians and pharmacists. It will also be helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology. .
Developmental neurobiology. --- Neurons -- physiology. --- Psychopharmacology. --- Psychophysiology. --- Mental illness --- Psychiatry and Psychology --- Central Nervous System --- Epidemiologic Factors --- Gonadal Hormones --- Therapeutics --- Nervous System --- Quality of Health Care --- Hormones --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Public Health --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Anatomy --- Health Care --- Chemicals and Drugs --- Sex Factors --- Brain --- Mental Disorders --- Drug Therapy --- Gonadal Steroid Hormones --- Medicine --- Psychiatry --- Health & Biological Sciences --- Psychiatry - General --- Neurology --- Physiological aspects --- Psychopharmacology --- Reproductive health. --- Sex differences. --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Behavioral pharmacology --- Drugs --- Health aspects --- Psychotropic effects --- Medicine. --- Pharmacy. --- Neurosciences. --- Endocrinology. --- Psychiatry. --- Reproductive medicine. --- Biomedicine. --- Reproductive Medicine. --- Health --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Chemistry --- Materia medica --- Internal medicine --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Endocrinology .
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