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Multiple sclerosis --- Multiple Sclerosis.

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Multiple sclerosis (MS) offers important challenges to understanding its complex genetics and molecular and immunological mechanisms, which eventually lead to relapsing and progressive clinical forms and a constellation of clinical manifestations. Along with the progress in knowledge, disease-modifying treatments and new therapeutic molecules have made an impact on the prognosis of the disease. Essential in the diagnostic identification process of MS is the differentiation of this major demyelinating disease with other inflammatory CNS disorders, including Neuromyelitis Optica and MOG antibody disease. MS is more prevalent in women; therefore, pregnancy and post-partum hormonal and immunological changes typically affect the clinical behavior of the disease. This Special Issue of Biomedicines addresses recent advances in the mechanistic genetic and immunological processes of MS, opening more options to future studies and to the consideration of further therapeutic possibilities. The issue discusses the application of modern therapies, including monoclonal antibodies, some still in the process of complete development, and the current strategies managing progressive MS. The aim of this issue is to stimulate basic and clinical research and promote observations on the ever-expanding and complex field of MS. Advancement in the understanding of the mechanisms and the clinical characterizations of this disease should result in improved therapeutic outcomes that reduce neurological and cognitive disability commonly associated with progressive disease.

Multiple sclerosis.

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Multiple sclerosis is among the most frequent neurological diseases, which affect seriously the quality of life of a constantly increasing number of patients, inducing physical and mental invalidism with indefinite perspectives. The ongoing investigation of the pathogenetic background and the inconclusive analysis of many pathophysiological mechanisms and serious neuropathological alterations of the disease are dominant crucial topics in the field of neurosciences, aimed at tracing a definite way to a therapeutic approach. The authors of this volume attempt to throw light on the labyrinth of multiple sclerosis, approaching the disease from the viewpoint of epidemiology, autoimmune reactions, symptomatology, mental and physical decline, diagnostic procedures, prognosis, and treatment. The authors submit herein, along with scientific data, their hope of contributing effectively to ameliorating the quality of life of those suffering from multiple sclerosis who wait patiently for the day of recovery.

Multiple sclerosis --- Multiple sclerosis --- Treatment.

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Multiple Sclerosis. --- Multiple sclerosis. --- Sclérose en plaques

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Les récits de personnes qui se sont rétablies des symptômes d'une sclérose en plaques invalidante se comptent sur les doigts de la main. Je suis un de ceux-là et ce livre est mon histoire. Voici un ouvrage inspirant destiné à toute personne impliquée dans une longue maladie, à son entourage et à ses thérapeutes. Il raconte la chute de l'auteur dans le labyrinthe de la maladie, ses désespoirs, et la manière curieuse dont il s'est pris en charge en apprenant à dormir, à faire de la thérapie et à danser. Oui, à danser. Danser en étant invalide et commencer à faire des choses impossibles, à partir de ce fameux jour où il a décidé de reprendre le contrôle de sa vie. Le lecteur intéressé par la PNL et par la danse des 5 Rythmes pourra considérer l’ouvrage comme un exemple concret d’application de ces pratiques thérapeutiques

Multiple sclerosis --- Self-care, Health