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Biological basis of detoxication
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ISBN: 0121550605 0323150101 Year: 1983 Publisher: New York, NY ; London : Academic Press,

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Metabolic basis of detoxication: metabolism of functional groups
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ISBN: 0123800609 0323137997 9780123800602 Year: 1982 Publisher: New York (N.Y.): Academic press,

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Metal ions in biological systems
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ISBN: 0824760298 082476028X 0824760301 082476031X 0824760328 0824772261 0824775929 0824776410 0824786394 0824793838 9780824760281 9780824760304 Year: 1974 Volume: v. 4 Publisher: New York (N.Y.): Dekker,

Biopharmaceutics and drug interactions
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ISBN: 0890047049 0090047049 Year: 1983 Publisher: New York : Raven Press,


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Drug interactions : a source book of adverse interactions, their mechanisms, clinical importance and management
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ISBN: 0632008431 Year: 1981 Publisher: Oxford,Boston : Blackwell Scientific Publications,

Molecular microbiology of heavy metals
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ISSN: 18625576 ISBN: 1280817739 9786610817733 3540697713 3540697705 364208916X Year: 2007 Volume: 6 Publisher: Berlin ; New York : Springer,

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Abstract

All forms of life depend on a variety of heavy metal ions. Nearly one-third of all gene products require a metal ion for proper folding or function. However, even metals generally regarded as non-poisonous are toxic at higher concentrations, including the essential ones. Thus, sensitive regulation of metal uptake, storage, allocation and detoxification is needed to maintain cellular homeostasis of heavy metal ions. Molecular Microbiology of Heavy Metals includes chapters on allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. Also discussed are metal bioreporters for the nanomolar range of concentration and tools to address the metallome. Chapters in the second part cover specific metals such as Fe, Mn, Cu, Ni, Co, Zn and Mo as key nutrient elements and Ag, As, Cd, Hg and Cr as toxic elements.

Keywords

Bacteria -- Metabolism. --- Bacterial proteins -- Metabolism. --- Cation transport proteins -- Metabolism. --- Heavy metals -- Metabolism. --- Metabolic detoxication, Drug. --- Metal ions -- Metabolic detoxification. --- Metal ions -- Metabolism. --- Metals, Heavy -- Metabolism. --- Molecular genetics. --- Metal ions --- Heavy metals --- Molecular genetics --- Ion Pumps --- Proteins --- Organisms --- Biotransformation --- Metabolic Phenomena --- Elements --- Metals --- Amino Acids, Peptides, and Proteins --- Inorganic Chemicals --- Phenomena and Processes --- Membrane Transport Proteins --- Chemicals and Drugs --- Membrane Proteins --- Carrier Proteins --- Metabolic Detoxication, Drug --- Metabolism --- Bacteria --- Cation Transport Proteins --- Metals, Heavy --- Bacterial Proteins --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Animal Biochemistry --- Microbiology & Immunology --- Metabolic detoxification --- Metabolism. --- Metabolic detoxification. --- Life sciences. --- Organometallic chemistry. --- Biochemistry. --- Microbiology. --- Bacteriology. --- Microbial genetics. --- Microbial genomics. --- Life Sciences. --- Biochemistry, general. --- Microbial Genetics and Genomics. --- Organometallic Chemistry. --- Genomics --- Microbial genetics --- Microorganisms --- Genetics --- Microbiology --- Microbial biology --- Biological chemistry --- Chemical composition of organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Chemistry, Organometallic --- Metallo-organic chemistry --- Chemistry, Organic --- Biosciences --- Sciences, Life --- Science --- Composition --- Molecular biology --- Ions --- Toxic metals --- Poisons --- Chemistry, Organic. --- Organic chemistry --- Organometallic chemistry .

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