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Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to obtain an overview of the recent changes that were made to the TGs during the recent round of revisions. It provides: 1) general background and historical information on the OECD genetic toxicology TGs; 2) a brief overview of the important types of genetic damage evaluated by these tests; 3) a description of the retained TGs; and 4) the issues and changes addressed therein during the revision process.

Genetic toxicology --- Genotoxicity --- Genotoxicology --- Toxicology --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Genetic aspects --- Genetic toxicology.

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Following the OECD Council decision, the Test Guideline 479 ‘Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells’ was deleted on 2nd April 2014.

Genetic toxicology --- Genotoxicity --- Genotoxicology --- Toxicology --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Genetic aspects

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Following the OECD Council decision, the Test Guideline 481 ‘Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay’ was deleted on 2nd April 2014.

Genetic toxicology --- Genotoxicity --- Genotoxicology --- Toxicology --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Genetic aspects

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Genetic toxicology --- Genomics --- Proteomics --- Genetic toxicology. --- Genomics. --- Proteomics. --- Genome research --- Genomes --- Genotoxicity --- Genotoxicology --- Toxicology --- Research --- Genetic aspects --- Molecular biology --- Proteins --- Molecular genetics --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis

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Genetic toxicology --- Genetics --- Research --- Genotoxicity --- Genotoxicology --- Toxicology --- Genetic aspects --- Genetic Structures --- Genetic Phenomena --- Biochemical genetics --- Medical genetics --- Carcinogenesis --- Chemical mutagenesis --- Mutagenesis. --- Toxicogenetics.