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Drug allergy.

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Drugs --- Drug allergy --- Médicaments --- Metabolism --- Dose-response relationship --- Métabolisme --- Relations dose-effet --- Drug allergy. --- Pharmacology --- Dose-response relationship. --- Metabolism. --- Textbooks & monographs 1891-2000 --- Textbooks & monographs 1891-2000. --- Médicaments --- Métabolisme

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The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine.  Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, the many different drug-induced systemic and cutaneous reactions, diagnoses, underlying mechanisms and structure-activity relationships.  Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs.  In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in the biomedical sciences and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.        .

Allergy. --- Anesthesiology. --- Dermatology. --- Drug allergy. --- Emergency medicine. --- Drug allergy --- Biochemical Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Hypersensitivity --- Immune System Diseases --- Chemical Phenomena --- Phenomena and Processes --- Diseases --- Diagnosis --- Structure-Activity Relationship --- Drug Hypersensitivity --- Medicine --- Health & Biological Sciences --- Clinical Immunology --- Medicine. --- Internal medicine. --- Respiratory organs --- Primary care (Medicine). --- Medicine & Public Health. --- Allergology. --- Pneumology/Respiratory System. --- Internal Medicine. --- Primary Care Medicine. --- Diseases. --- Allergy --- Drugs --- Idiosyncratic drug reactions --- Side effects --- Pneumology. --- Skin --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Allergic diseases --- Allergies --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Anaesthesiology --- Surgery --- Respiratory organs—Diseases. --- Primary medical care --- Medical care

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The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

Allergy. --- Respiratory organs—Diseases. --- Primary care (Medicine). --- Dermatology. --- Anesthesiology. --- Allergology. --- Pneumology/Respiratory System. --- Primary Care Medicine. --- Primary medical care --- Medical care --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Anaesthesiology --- Surgery --- Medicine --- Skin --- Diseases --- Drug allergy. --- Allergy --- Drugs --- Idiosyncratic drug reactions --- Side effects --- Respiratory organs --- Pneumology. --- Diseases. --- Respiratory diseases

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The use of medications globally is increasing, and as the baby boomer cohort ages, more people will survive with chronic illnesses managed with an ever more complex cocktail of pharmaceutical treatments. This book covers all aspects of the most challenging dilemmas, that of allergic and toxic reactions to drugs. Cutaneous Drug Eruptions: Diagnosis, Histopathology and Therapy is an accessible resource for early detection and resolution of cutaneous drug reactions. It provides dermatologists, primary care physicians and all medical personnel with access to comprehensive and practical clinical information that will help them identify and appropriately manage all incidences of skin conditions and disease that relate to the use of drugs.

Medicine & Public Health. --- Dermatology. --- Drug Safety and Pharmacovigilance. --- Allergology. --- Medicine. --- Allergy. --- Médecine --- Allergie --- Dermatologie --- Dermatology --- Medicine --- Health & Biological Sciences --- Drug-exanthems --- Diagnosis. --- Treatment. --- Dermatitis medicamentosa --- Drug-eruptions --- Pharmacy. --- Dermatopharmacology --- Drug allergy --- Drugs --- Pharmacology --- Skin --- Toxicology --- Diseases --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Chemistry --- Materia medica --- Side effects. --- Adverse drug reactions --- Adverse reactions to drug therapy --- Chemotherapy --- Drug-induced disease --- Drug side effects --- Side effects of drugs --- Iatrogenic diseases --- Drug interactions --- Complications --- Adverse reactions --- Physiological effect