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The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics.Key Features* Covers all aspects of the aging skeleton in one comprehensive volume* Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass* Provid
Bone and Bones --- Aging --- Osteoporosis --- physiology --- Bone Diseases --- Aged --- Skeleton --- ELSEVIER-B EPUB-LIV-FT --- Aging. --- Osteoporosis. --- physiology. --- Bones --- Osteology --- Musculoskeletal system --- Bone --- Bone aging --- Diseases --- Age factors. --- Aging - physiology
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Cognitive reserve has emerged as a powerful concept for interpreting individual differences in susceptibility to, and recovery from, brain injury or pathology. Underlying cognitive reserve is the idea that individual differences in how cognitive tasks are mediated in the brain allow some people to cope with pathology to a greater degree than others. Cognitive Reserve: Theory and Applications describes in depth the source of these individual differences. This volume provides a comprehensive review of theory, research and clinical application of the cognitive reserve. Chapters explore the theoretical underpinnings of cognitive reserve, and evidence for its existence. Various approaches for studying this concept are addressed, including epidemiologic, cognitive experimental, and neuroimaging. Possible genetic and physiologic underpinnings of cognitive reserve are presented. Application of this concept to a wide range of situations, including child development, aging, Alzheimer’s disease, stroke, HIV, and head injury is discussed. The result is an up-to-date, global treatment of cognitive reserve that will be of interest to someone new to the concept or the experienced investigator.
Cognition Disorders --- Aging --- Alzheimer Disease --- Brain --- Brain Injuries --- Cognition --- Neuropsychological Tests. --- Cognition disorders --- Neuropsychology. --- Troubles de la cognition --- Neuropsychologie --- diagnosis. --- physiology. --- physiopathology. --- Diagnosis. --- Diagnostic --- Neuropsychology --- Neuropsychological Tests --- Diagnosis --- diagnosis --- physiology --- physiopathology --- Cognition disorders - Diagnosis --- Cognition Disorders - diagnosis --- Aging - physiology --- Alzheimer Disease - diagnosis --- Brain - physiology --- Brain Injuries - physiopathology --- Cognition - physiology
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In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process. Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice. Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.
Aging -- physiology. --- Aging. --- Life Expectancy. --- Life spans (Biology). --- Aging --- Life spans (Biology) --- Vital Statistics --- Biological Science Disciplines --- Growth and Development --- Data Collection --- Natural Science Disciplines --- Physiological Processes --- Demography --- Epidemiologic Measurements --- Epidemiologic Methods --- Population Characteristics --- Physiological Phenomena --- Disciplines and Occupations --- Information Science --- Public Health --- Investigative Techniques --- Health Care --- Phenomena and Processes --- Environment and Public Health --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Life Expectancy --- Physiology --- Medicine --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Geriatrics --- Biophysics --- Span of life (Biology) --- Spans, Life (Biology) --- Age --- Ageing --- Senescence --- Physiological effect --- Medicine. --- Geriatrics. --- Pathology. --- Medicine & Public Health. --- Geriatrics/Gerontology. --- Life (Biology) --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease
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Essentials of Palliative Care is a to-the-point, clinically oriented resource for all members of the multidisciplinary palliative care team and trainees. It covers practical clinical topics, including assessment of the patient and pain and symptom management, and practical non-medical topics central to providing effective palliative care, including psychological management, guidance on how to help patients and their families through the many healthcare decision points they face, and sensitivity to the goals and culture of the patient. Review questions, with detailed answers, provide a convenient way for readers to test their knowledge. Features: · Concise, comprehensive, clinically focused · Multiple choice review questions, with detailed answers · Expert contributors from leading institutions · Coordination of care by palliative care team a major focus.
Aged. --- Aging -- Physiology. --- Aging -- Psychology. --- Geriatrics. --- Palliative treatment --- Terminally ill --- Hospice care --- Terminal Care --- Patient Care --- Therapeutics --- Health Services --- Health Care Facilities, Manpower, and Services --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care --- Palliative Care --- Hospice Care --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Pathology --- Anesthesiology --- Care --- Palliative treatment. --- Terminal care. --- End-of-life care --- Palliation (Medical care) --- Palliative care --- Palliative medicine --- Care and treatment --- Medical care --- Medicine. --- Anesthesiology. --- Critical care medicine. --- Internal medicine. --- Nursing. --- Pain medicine. --- Medicine & Public Health. --- Pain Medicine. --- Intensive / Critical Care Medicine. --- Internal Medicine. --- Care of the sick --- Critical care medicine --- Death --- Clinical nursing --- Nurses and nursing --- Nursing process --- Medicine, Internal --- Intensive care --- Intensive medicine --- Emergency medicine --- Intensive care units --- Anaesthesiology --- Surgery --- Algiatry
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“Aged? But he does not appear aged, just look, his hair has remained young!” Marcel Proust, In Search of Lost Time (1913–27) The appearance of hair plays an important role in peoples’ overall physical appe- ance and self-perception. With today’s increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the “secret life” of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).
Aged. --- Aging -- physiology. --- Hair -- Diseases. --- Hair Diseases. --- Older people -- Health and hygiene. --- Hair --- Older people --- Adult --- Integumentary System --- Growth and Development --- Aged --- Aging --- Anatomy --- Age Groups --- Physiological Processes --- Physiological Phenomena --- Persons --- Phenomena and Processes --- Named Groups --- Medicine --- Dermatology --- Geriatrics --- Health & Biological Sciences --- Diseases --- Health and hygiene --- Diseases. --- Health and hygiene. --- Medicine. --- Dermatology. --- General practice (Medicine). --- Geriatrics. --- Medical research. --- Quality of life. --- Medicine & Public Health. --- Geriatrics/Gerontology. --- General Practice / Family Medicine. --- Quality of Life Research. --- Family medicine. --- Quality of Life --- Research. --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Gerontology --- Skin --- Biomedical research --- Medical research
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Berries are popularly consumed worldwide as fresh, processed, and other derived forms. Research conducted over the last decade and a half has provided significant and convincing evidence to support the cancer preventive potential of these colorful fruits. Berries and their phytochemical constituents work through multiple mechanisms to reduce the malignant properties of cancer cells in laboratory studies. Further, diets of various berry formulations, including freeze dried berries, have been shown to prevent cancer in animals, and recent data indicate that they also exhibit cancer preventive effects in humans. Providing an unprecedented compilation of current information, this book, Berries and Cancer Prevention: 1) Describes the major groups of bioactive compounds in berries and their antioxidant potential 2) Describes the cancer inhibitory effects of berry extracts and individual components in vitro, and discusses their mechanisms of action on a cellular and molecular level 3) Discusses the cancer-inhibitory effects of berries and berry components on tumor development in animals 4) Discusses recent results on the cancer-inhibitory effects of berries and berry components in humans and describes their mechanisms of action; 5) Discusses the relative merits of the use of whole berries, freeze-dried berries, berry extracts and individual berry components for cancer prevention, particularly in humans. The editors anticipate that this book would be useful for researchers, academicians and trainees associated with departments of nutrition, dietetics, food science and technology, cancer biology, cancer prevention, public health, family medicine, osteopathy, dentistry, etc. It should also be useful for practitioners, dieticians, and others involved in daily patient health care. We also expect that individuals involved in various roles in the berry industry including berry production, product development, marketing and sales, would benefit from this book. The public has a strong interest in healthy foods and dietary interventions for cancer prevention, and we hope that many of those individuals will also find this book of great interest.
Age Factors. --- Aging -- Congresses. --- Aging -- physiology. --- Health. --- Life Expectancy. --- Longevity -- Congresses. --- Older people -- Diseases -- Alternative treatment. --- Cancer --- Functional foods --- Diseases --- Nutrition Therapy --- Plant Components, Aerial --- Food --- Plant Structures --- Food and Beverages --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Technology, Industry, Agriculture --- Anatomy --- Fruit --- Diet Therapy --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Diet therapy --- Alternative treatment --- Berries --- Black raspberries. --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Blackcap --- Rubus occidentalis --- Scotch cap --- Thimbleberry --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Prevention. --- Chemoprovention. --- Research. --- Therapeutic use. --- Analysis. --- Physiological effect. --- Composition --- Medicine. --- Cancer research. --- Pharmacology. --- Oncology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Biology --- Chemistry --- Medical sciences --- Raspberries --- Rubus --- Fruit-culture --- Tumors --- Oncology . --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
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