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Book
Atomic Force Microscopy Investigations into Biology : From Cell to Protein
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ISBN: 9535152289 9535101145 Year: 2012 Publisher: IntechOpen

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Abstract

The atomic force microscope (AFM) has become one of the leading nanoscale measurement techniques for materials science since its creation in the 1980's, but has been gaining popularity in a seemingly unrelated field of science: biology. The AFM naturally lends itself to investigating the topological surfaces of biological objects, from whole cells to protein particulates, and can also be used to determine physical properties such as Young's modulus, stiffness, molecular bond strength, surface friction, and many more. One of the most important reasons for the rise of biological AFM is that you can measure materials within a physiologically relevant environment (i.e. liquids). This book is a collection of works beginning with an introduction to the AFM along with techniques and methods of sample preparation. Then the book displays current research covering subjects ranging from nano-particulates, proteins, DNA, viruses, cellular structures, and the characterization of living cells.

The world of nano-biomechanics : mechanical imaging and measurement by atomic force microscopy
Author:
ISBN: 128109627X 9786611096274 0080556043 044452777X 9780444527776 9780080556048 9780444636867 0444636862 Year: 2008 Publisher: Amsterdam ; Oxford : Elsevier,

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By using nanotechnological methods, we can now poke around protein molecules, genes, membranes, cells and more. Observation of such entities through optical and electron microscopes tempt us to touch and manipulate them. It is now possible to do so, and scientists around the world have started pulling, pushing and cutting small structures at the base of life processes to understand the effect of our hand work.The book describes the physical properties of such life supporting structures from the molecular level with a special emphasis on their designs based on the mechanical strength an


Book
Atomic-force Microscopy and Its Applications
Authors: --- --- ---
ISBN: 178985170X 1789851696 183881776X Year: 2019 Publisher: IntechOpen

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Atomic force microscopy is a surface analytical technique used in air, liquids or a vacuum to generate very high-resolution topographic images of a surface, down to atomic resolution. This book is not only for students but also for professional engineers who are working in the industry as well as specialists. This book aims to provide the reader with a comprehensive overview of the new trends, research results and development of atomic force microscopy. The chapters for this book have been written by respected and well-known researchers and specialists from different countries. We hope that after studying this book, you will have objective knowledge about the possible uses of atomic force microscopy in many scientific aspects of our civilisation.


Book
High-speed atomic force microscopy in biology : directly watching dynamics of biomolecules in action
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ISBN: 9783662647851 Year: 2022 Publisher: Berlin, Germany : Springer,

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Book
Contact problems for soft, biological and bioinspired materials
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ISBN: 3030851745 3030851753 Year: 2022 Publisher: Cham, Switzerland : Springer,

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This book contains contributions from leading researchers in biomechanics, nanomechanics, tribology, contact mechanics, materials science and applications on various experimental techniques including atomic force microscopy (AFM) for studying soft, biomimetic and biological materials and objects. Biologists, physicists, researchers applying methods of contact mechanics and researchers testing materials using indentation techniques along with many other applied scientists will find this book a useful addition to their libraries. Moreover, several reviews in this book are written as introductions to several important and rather sophisticated research areas such as depth-sensing indentation, studying of biological cells by AFM probes, mechanics of adhesive contact and contact between viscoelastic (hereditary elastic) solids. The book containing new theoretical models, results of experimental studies and numerical simulations, along with reviews of above mentioned areas of contact mechanics in application to biological systems, would be beneficial for researchers in many areas of biology, medicine, engineering, mechanics and biomimetics.


Book
Atomic Force Microscopy in Molecular and Cell Biology
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ISBN: 9811315108 9811315094 Year: 2018 Publisher: Singapore : Springer Singapore : Imprint: Springer,

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The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used to detect the superstructures of the cell membrane, cell morphology, cell skeletons and their mechanical properties. Opening up new fields of in-situ dynamic study for living cells, enzymatic reactions, fibril growth and biomedical research, these combined techniques will yield valuable new insights into molecule and cell biology. This book offers a valuable resource for students and researchers in the fields of biochemistry, cell research and chemistry etc.


Book
Imaging and Manipulation of Adsorbates Using Dynamic Force Microscopy : Proceedings from the AtMol Conference Series, Nottingham, UK, April 16-17, 2013
Authors: --- ---
ISBN: 9783319174013 3319174002 9783319174006 3319174010 Year: 2015 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Imaging and Manipulation of Adsorbates using Dynamic Force Microscopy provides an overview of the latest developments in dynamic force microscopy (DFM) of atoms, molecules, and nanoparticles adsorbed on solid surfaces. Significant advances in the capabilities of this technique have been made in the last decade and this book represents a timely snapshot of the major research themes in the field, with a particular focus on the manipulation of matter at the atomic and (sub)molecular levels. This edited volume will be of keen interest to researchers active in nanoscience and its various sub-fields including, in particular, scanning probe microscopy.  This book expands on the previous volumes in the series Advances in Atom and Single Molecule Machines.


Book
Scanning Probe Microscopy : Atomic Force Microscopy and Scanning Tunneling Microscopy
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ISBN: 9783662452400 3662452391 9783662452394 3662452405 Year: 2015 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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This book explains the operating principles of atomic force microscopy and scanning tunneling microscopy. The aim of this book is to enable the reader to operate a scanning probe microscope successfully and understand the data obtained with the microscope. The chapters on the scanning probe techniques are complemented by the chapters on fundamentals and important technical aspects. This textbook is primarily aimed at graduate students from physics, materials science, chemistry, nanoscience and engineering, as well as researchers new to the field.


Book
Microscopic Techniques for the Non-Expert
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ISBN: 3030995410 3030995429 Year: 2022 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book covers fundamental microscopic techniques for Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), and other microscopic tools. It provides step-by-step instructions and explanations of the basic fundamental concepts and mechanisms and guides the reader on resolving queries related to taking and analyzing microscopy images. The latest advancements and developments in microscopic equipment are described. Theoretical background on microscopy is also provided to enhance the reader’s understanding of microscopy techniques and tools. Microscopic Techniques for the Non-Expert is an ideal book for undergraduate and postgraduate students, as well as researchers with a background in environmental science, materials science, biomedicine, engineering, or bio-nanotechnology.

Atomic force microscopy, scanning nearfield optical microscopy and nanoscratching : application to rough and natural surfaces
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ISBN: 1280657170 9786610657179 3540284729 3540284052 Year: 2006 Publisher: Berlin : Springer-Verlag,

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Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applications of the supermicroscopies AFM and SNOM, and of the nanomechanical testing on rough and technical natural surfaces in the submicron range down to a lateral resolution of a few nm. New or improved instrumentation, new physical laws and unforeseen new applications in all branches of natural sciences (around physics, chemistry, mineralogy, materials science, biology and medicine) and nanotechnology are covered as well as the sources for pitfalls and errors. It outlines the handling of natural and technical samples in relation to those of flat standard samples and emphasizes new special features. Pitfalls and sources of errors are clearly demonstrated as well as their efficient remedy when going from molecularly flat to rough surfaces. The academic or industrial scientist learns how to apply the principles for tackling their scientific or manufacturing tasks that include roughness far away from standard samples.

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