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The purpose of this book is to provide information on apoptotic processes involved in major neoplastic diseases and their translations into emerging anti-cancer strategies. The book is divided into 15 chapters, each of which will be focused on one particular cancer (breast, bladder, cervical, colorectal, esophageal, gastric, laryngeal, liver, lung, nasopharyngeal, pancreatic, prostate, thyroid, leukemia and cutaneous malignant melanoma). A number of established leaders in the field have critically summarized the recent discoveries concerning apoptosis in a particular cancer and its potential for anti-cancer treatment. The book describes how the apoptosis plays a role in the specific carcinogen-induced cellular and molecular changes during the development of the cancer, and critically discusses how the emerging anti-cancer strategy can be built by the utilization of the specific carcinogen-related apoptotic pathway. Therefore, this book will be not only for laboratory-based molecular and cell biologists and biochemists in cancer research but also for clinical oncologists and those working in the pharmaceutical and biotechnological industries.

Apoptosis. --- Cancer --Chemotherapy. --- Carcinogenesis. --- Carcinogenesis --- Apoptosis --- Cancer --- Neoplastic Processes --- Cell Death --- Diseases --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Cell Physiological Processes --- Pathologic Processes --- Pathological Conditions, Signs and Symptoms --- Cell Physiological Phenomena --- Phenomena and Processes --- Cell Transformation, Neoplastic --- Neoplasms --- Drug Therapy --- Medicine --- Health & Biological Sciences --- Oncology --- Chemotherapy --- Cell death. --- Cell degeneration --- Medicine. --- Cancer research. --- Pharmacology. --- Oncology. --- Surgical oncology. --- Biomedicine. --- Cancer Research. --- Surgical Oncology. --- Pharmacology/Toxicology. --- Cell death --- Cells --- Death (Biology) --- Oncology  . --- Cytology. --- Toxicology. --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Cell biology --- Cellular biology --- Biology --- Cytologists --- Tumors --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Excision --- Treatment --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Drugs --- Pharmacy --- Cancer research --- Physiological effect

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The question of sustainability in the open access movement has been widely debated, yet satisfactory answers have yet to be generated: How do we move from an approach entirely based on temporary projects to an approach based on community-based sustainable infrastructure? What kinds of social and technical infrastructures could support the Knowledge Commons? What values and services are being delivered, by which stakeholders, and for whom? What governance and financial models are possible? Given the global nature of scholarly communication, how do we ensure that the designs of the Commons are inclusive of voices from the global South? This volume collects nine selected papers presented at ELPUB2018 Conference in June 2018 in Toronto. Each paper was carefully selected, reviewed and edited to bring to an international audience the latest contributions from researchers and experts in the field. In addition to the technical issues related to interoperability of systems, research workflow, content preservation, and other services, the selected papers address the design and implementation of a community-based research communication infrastructure. ELPUB Conference has featured research results in various aspects of digital publishing for over two decades, involving a diverse international community of librarians, developers, publishers, entrepreneurs, administrators and researchers across the disciplines in the sciences and the humanities.

Information Science & Library Science --- inclusive knowledge infrastructures --- institutional repository --- open access --- open data --- open science --- research infrastructure --- electronic publishing --- knowledge production --- knowledge common --- sustainability