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Nées dans la tourmente et le doute, les manipulations génétiques inquiètent, leur essor fantastique les a menées aux portes de l'humain. Les chercheurs et les médecins se contenteront-ils de soigner l'homme par les gènes et de soigner les gènes eux-mêmes ou bien céderont-ils à la tentation de modifier le programme humain pour créer un autre modèle ?

Molecular biology --- Genetic engineering --- Human genetics --- Génie génétique --- Génétique humaine --- Manipulations genetiques. --- menselijk genoom --- genetische engineering (manipulatie) --- génome humain --- génie génétique (ingénierie génétique) --- Genetic engineering. --- Biotechnology. --- Human genetics. --- Génie génétique --- Génétique humaine --- Methods

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From the discovery of the double helix to the imminent sequencing of the human genome, James Watson has been at dead center in this great biological revolution. Since the very morning after his Nobel Prize-winning discovery, he has continued to ride the scientific supernova that he and his collaborator, Francis Crick, detonated in 1953. Targeting the big questions, mobilizing the best talent, writing the textbook that defined molecular biology, energizing the "war on cancer," he has served as a prime mover of the DNA era. Now, a distinguished science reporter who has known him for decades and worked for him for four years, with unique access to the scientists who know Watson best, has written an unauthorized, non-reverential account of this extraordinary man. While Watson is probably the most influential scientist in the last half-century, he is also one of the most controversial. From the ruthless competition in the race to identify the structure of DNA, to clashes with ethicists over charged issues in genetics, to a chorus of Bronx cheers for his recent memoir, Watson has left a wake of detractors as well as fans. Until now, Watson has managed to keep control over his legend, fending off aspiring biographers with his own memoirs. Victor McElheny gets behind this invented persona, bringing us close to the relentless genius who triggered and sustained a revolution in science that affects us all. Shares the story of the Nobel Prize-winning scientist, covering his role in the race to identify the structure of DNA, his clashes with ethicists over genetics issues, and his own memoirs.

Molecular biologists --- Molecular genetics. --- DNA --- Molecular Biology --- history. --- moleculaire biologie --- menselijk genoom --- biologie moléculaire --- ADN --- génome humain --- Dna --- Molecular biology --- History. --- Molecular genetics --- Genetics --- Biologists --- Watson, James D., --- Watson, J. D.

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Le développement de la connaissance du génome rend de plus en plus performante l'interprétation des résultats biologiques de l'étude du polymorphisme de l'ADN, confirmant l'individualité biologique de l'être.

DNA fingerprinting --- Empreintes génétiques --- Criminologie --- Recht --- Desoxyribonucleïnezuur (DNA) --- Genetica --- menselijk genoom --- genetische vingerafdruk (DNA-identificatie) --- bio-ethiek (medische, biomedische ethiek, bio-ethische aspecten) --- Droit --- Acide désoxyribonucléique (ADN) --- Génétique --- génome humain --- empreinte génétique --- bioéthique (éthique médicale, biomédicale, aspects bioéthiques) --- Empreintes génétiques

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Human genetics is not the playground of science alone. Genetics concerns all of us, for we all have DNA, genes, genomes, and chromosomes. Our genes determine partly our appearance and our behaviour, our talents and our health risks.The authors of The Human Recipe use humour to explain what we understand about human genetics. With anecdotes and topical examples, they demonstrate how genetics affects our everyday lives. What if a DNA analysis were to reveal that your biological father must be someone other than the person you’ve been calling “Dad” for years? Does genetics explain why Africans excel in athletics, Asians in gymnastics, and Europeans mainly in sports testing physical strengths? What is the difference between a genetic disease and a contagious illness?The newest developments in human genetics also raise ethical questions and issues which are currently being debated within the genetics community, and the authors do not avoid looking at these either. Should we use genetics to ensure the conception of healthy children or even “designer babies”? Should we identify genetic risks before pregnancy? Should we edit genes in embryos? Can we identify our risk for cancers and can we prevent them? What about privacy in DNA research and forensic databases? Can DNA be stolen, and if so, would this be considered a serious crime? The Human Recipe provides a clever insight into all you might want to know about human genetics in our current society.

Human genome --- Genes --- Genetics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Units of heredity --- Units of inheritance --- Molecular genetics --- DNA --- Genomes --- Human chromosomes --- Social aspects. --- menselijk genoom --- genetica (genen) --- genetisch onderzoek --- genetisch patent --- génome humain --- génétique (gènes) --- recherche génétique --- brevet génétique --- Genetica --- Genetisch onderzoek --- Human genetics --- Genetics

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The Human Genome Project, discoveries in molecular biology and new reproductive technologies have advanced our understanding of how genetic science may be used to treat persons with genetic disorders. Greater knowledge may also make possible genetic interventions to "enhance" normal human characteristics, such as height, hair or eye colour, strength, or memory, as well as the transmittal of such modifications to future generations. The prospect of inheritable genetic modifications, or IGMs, whether for therapeutic or enhancement purposes, raises complex scientific, ethical and regulatory issues. This volume presents 20 essays by physicians, scientists, philosophers, theologians, lawyers and policy analysts addressing these issues from diverse perspectives. In three sections, the authors discuss the short- and long-term scientific feasibility of IGM technology; ethical and religious issues related to safety, justice, morality, reproductive rights, and enhancement; and regulatory issues including the necessity of public input and oversight and the influence of commercialization. Their goal is to open a dialogue engaging not only scholars and scientists but also government officials and concerned citizens. The authors conclude that while IGM cannot be carried out safely and responsibly on humans utilizing current methods, it is important to begin public discussion now to determine whether, and if so how, to proceed. The prospect of inheritable genetic modifications for therapeutic or enhancement purposes raises complex scientific, ethical and regulatory issues. These 20 essays, by physicians, lawyers, theologians and others, address these issues from a variety of perspectives.

Bioethical Issues. --- Genetic Engineering. --- Genetic engineering --- Genetic engineering. --- Medical genetics. --- Public policy. --- Government policy --- Moral and ethical aspects. --- menselijk genoom --- gentherapie --- ethiek (ethische aspecten) --- godsdienst (religie, religieuze aspecten) --- génome humain --- thérapie génique --- ethique (aspects ethiques) --- religion (aspects religieux) --- Medical genetics --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Moral and ethical aspects --- Genetic aspects