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Seit 2014 arbeitet das Netzwerk Human Cities an Challenging the City Scale: einem geförderten EU-Projekt im Rahmen von Creative Europe, unter der Leitung von Cité du design Saint-Étienne. Verschiedene Stadtexperimente in elf europäischen Städten sollten die Bürger dazu befähigen, die Räume, in denen sie leben, arbeiten und ihre Freizeit verbringen, neu zu denken und aktiv mitzugestalten. In Gesprächen mit Beteiligten wurde untersucht, wie solche Bottom-up-Prozesse mit ihren Werkzeugen und Instrumenten neue Ideen für die Zusammenarbeit zwischen Bewohnern und Stadtverwaltung liefern können. Das Buch bietet eine Vielzahl von Inspirationen und Erkenntnissen für all die Planer und Politiker, Praktiker und aktiven Bürger, die neue Wege suchen, um gemeinsam menschliche Städte zu erschaffen. Since 2014, the Human Cities network has been working on Challenging the City Scale: a pan-European project led by Cité　du design Saint-Étienne and supported by the Creative Europe programme to question the urban scale and investigate co-creation in cities. The Human Cities partners have carried out urban experimentations in 11 European cities empowering citizens to rethink the spaces in which they live, work and spend their leisure time. Through conversations with people involved, the book examines how bottom-up processes and their design, tools and instruments generate new ideas to reinvent the city. It offers inspiration and insights to everyone, from practitioners and politicians to designers and active citizens, eager to try out new ways to produce more human cities together.

Bottom-up. --- Cities. --- Civil Participation. --- Clear Village. --- Human. --- Urban planning. --- ARCHITECTURE / Regional.

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Environmental Sciences and Forestry. Forestry --- Silviculture --- Tropical Silviculture --- Tropical Silviculture. --- TROPICAL RAIN FORESTS --- PULPWOOD --- CLEAR FELLING --- PAPUA NEW GUINEA --- LOGGING --- ENVIRONMENTAL IMPACT --- SOCIAL COSTS

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Surgical and medical oncologists have been unable to decrease renal cell carcinoma mortality for uncertain reasons, although a lot of progress has been made in diagnosis and imaging, recognition of different genetic and pathological entities, management of localized disease and in the research on new drug treatments for advanced stages of the disease, potentially combined with surgery. The purpose of this book, which tackles a number of separate interesting topics, is to provide further insight into the disease and the management of early and advanced renal cell carcinoma. The volume is divided into different parts; the first part covers the characterization of renal masses and the second part covers rare distinct pathological entity. In the management section, active surveillance, partial nephrectomy and radiofrequency ablation are presented. A separate chapter reviews the management of Von Hippel Lindau disease, and finally, conventional and aberrant signaling pathways are explored.

Oncology. --- Carcinoma, Renal Cell. --- Tumors --- Adenocarcinoma Of Kidney --- Adenocarcinoma, Renal --- Chromophil Renal Cell Carcinoma --- Chromophobe Renal Cell Carcinoma --- Clear Cell Renal Carcinoma --- Clear Cell Renal Cell Carcinoma --- Collecting Duct Carcinoma --- Collecting Duct Carcinoma (Kidney) --- Collecting Duct Carcinoma of the Kidney --- Nephroid Carcinoma --- Papillary Renal Cell Carcinoma --- Renal Cell Cancer --- Renal Cell Carcinoma --- Renal Cell Carcinoma, Papillary --- Renal Collecting Duct Carcinoma --- Sarcomatoid Renal Cell Carcinoma --- Adenocarcinoma, Renal Cell --- Carcinoma, Hypernephroid --- Grawitz Tumor --- Hypernephroma --- Renal Carcinoma --- Adenocarcinoma Of Kidneys --- Adenocarcinomas, Renal Cell --- Cancer, Renal Cell --- Carcinoma, Collecting Duct --- Carcinoma, Collecting Duct (Kidney) --- Carcinoma, Nephroid --- Carcinoma, Renal --- Carcinomas, Collecting Duct --- Carcinomas, Collecting Duct (Kidney) --- Carcinomas, Renal Cell --- Collecting Duct Carcinomas --- Collecting Duct Carcinomas (Kidney) --- Hypernephroid Carcinoma --- Hypernephroid Carcinomas --- Hypernephromas --- Kidney, Adenocarcinoma Of --- Nephroid Carcinomas --- Renal Adenocarcinoma --- Renal Adenocarcinomas --- Renal Carcinomas --- Renal Cell Adenocarcinoma --- Renal Cell Adenocarcinomas --- Renal Cell Cancers --- Renal Cell Carcinomas --- Tumor, Grawitz --- Oncology

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Renal cancer is a health problem of major concern worldwide. Although tyrosine kinase inhibitors and immune check-point blockade treatments, alone or in combination, are giving promising results, failures are quite frequent due to intratumor heterogeneity and to the acquisition of drug resistance. The spectrum of renal cell carcinoma subtypes is wide. Up to 70–80% of renal tumors are clear cell renal cell carcinomas, a clinically aggressive tumor subtype linked to VHL gene inactivation. Next in frequency, the papillary renal cell carcinoma category encompasses an intricate puzzle of classic and newly described entities with poorly defined limits, some of them pending definite clarification. Likewise, the chromophobe–oncocytoma duality, the so-called hybrid tumors and oncocytic neoplasms, remain to be well profiled. Finally, a growing list of very uncommon renal tumors linked to specific molecular signatures fulfill the current portrait of renal cell neoplasia. This Special Issue of Cancers regards RCC from very different perspectives, from the intimate basic mechanisms governing this disease to the clinical practice principles of their diagnoses and treatments. The interested reader will have the opportunity to contact with some of the most recent findings and will be updated with excellent reviews.

Renal cell carcinoma. --- Kidneys --- Cancer. --- Adenocarcinoma of kidney --- Clear cell carcinoma --- Grawitz tumor --- Grawitz's tumor --- Hypernephroid carcinoma --- Hypernephroma --- Renal adenocarcinoma --- Renal cell adenocarcinoma --- Cancer --- N-glycomapping --- n/a --- SMAD proteins --- patient survival --- pro-IL-1? --- survival prediction --- inflammation markers --- tumor migration --- prognostic factors --- practical approach --- circular RNAs in a clinico-genomic predictive model --- glycomarkers --- review --- nephrectomy --- uric acid --- VEGF inhibitors --- metabolic reprogramming --- collecting duct carcinoma --- curcumin --- metabolome profiling --- identification of circular RNAs --- IL-2 --- experimental validation of circular RNA --- Raf/MEK/ERK --- HOT --- PI3K/Akt/mTOR --- pentose phosphate pathway --- kidney cancer --- LOT --- mutation --- RCC --- polybromo-1 --- pale cell --- MMP-9 --- gene expression --- recurrence free survival --- chromosomal loss --- IL-1? --- chronic kidney disease --- glutathione transferase omega 2 --- label-free --- glutathione transferase omega 1 --- emerging entity --- copy number alteration --- FOXO3 --- predictive role --- tumor slice culture --- tyrosine kinase inhibitors --- PPP --- ESC --- CDKN1A expression --- metastasis --- PD-L1 --- diagnostic and prognostic markers --- EVI1 --- copy number loss --- RNA sequencing --- NK cells --- glutathione metabolism --- clear cell renal cell carcinoma --- renal cell cancer --- proliferation --- eosinophilic variant --- Xp11 translocation renal cell carcinoma --- prognosis --- invasion --- immune infiltration --- IL4R? --- FISH --- 11) translocation renal cell carcinoma --- tumor microenvironment --- metabolome --- hyperosmolality --- toxicity --- ALK --- drug sensitivity --- t(6 --- copy number analysis --- urine --- genetic association --- polymorphism --- solute carrier proteins --- kidney --- metastatic ccRCC --- molecular genetic features --- recurrence-free survival --- chromophobe renal cell carcinoma --- unclassified renal tumor --- overall survival --- mTOR inhibitors --- mTOR --- JAK2 --- von Hippel–Lindau --- miR-155-5p --- glycoproteomics --- PBRM1 --- miR-133b --- survival --- TFE3 --- TFEB --- oncocytic renal tumor --- immune checkpoint inhibitors --- biomarker --- MMP10 --- TCGA --- ghrelin --- EMT like --- checkpoint inhibitors --- MiT family translocation renal cell carcinoma --- gene signature --- sarcomatoid --- transforming growth factor beta --- clear cell Renal Cell Carcinoma --- tumor adhesion --- renal cancer --- unclassified renal cell carcinoma --- Papillary renal cell carcinoma (pRCC) --- miR-146a-5p --- renal cell --- everolimus --- integrins --- cytoreductive nephrectomy --- immunotherapy --- predictive factors --- immunohistochemistry --- MTA2 --- IL13R?1 --- targeted therapy --- intratumour heterogeneity --- aurora A --- TCA cycle --- AMP-activated protein kinases --- cancer-specific survival --- programmed death-ligand 1 --- efficacy --- renal cell carcinoma --- anaplastic lymphoma kinase rearrangement --- TFEB-amplified renal cell carcinoma --- statins --- cancer immunotherapy --- microRNA --- new entity --- proteome profiling --- von Hippel-Lindau

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For several decades the writings of sociologist Neil J. Smelser have won him a vast and admiring audience across several disciplines. Best known for his work on social movements, economic sociology, and British social history, Smelser's psychoanalytic writings are less familiar to his readers. In fact, many people are completely unaware of Smelser's formal psychoanalytic training and ongoing counseling practice. With the publication of The Social Edges of Psychoanalysis, Smelser's thought-provoking essays on psychoanalytic concepts are finally brought together in one book. Psychoanalytic theory has had an ambivalent relationship with sociology, and these essays explore that ambivalence, providing arguments about how and why psychoanalytic approaches can deepen the sociological perspective. One of Smelser's main tenets is that human social behavior always contains both social-structural and social-psychological elements, and that psychoanalytic theory can bridge these two dimensions of human social life. Many of the issues Smelser addresses--including interdisciplinarity, the macro-micro link in research, masculinity and violence, and affirmative action--have generated considerable scholarly interest. This collection paves the way for further articulation of the relationship between sociology and psychoanalysis at a time when many sociologists are looking for interdisciplinary links in their work. Presented with clarity and grace, and free of the murkiness often found in both sociological and psychoanalytic writing, Smelser's new book will excite reflection and research on the less visible dynamics of social existence.

Social sciences and psychoanalysis. --- Social sciences and psychoanalysis --- Social Sciences --- Psychoanalysis --- Anthropology, Education, Sociology and Social Phenomena --- Psychiatry --- Behavioral Sciences --- Behavioral Disciplines and Activities --- Psychiatry and Psychology --- Psychology --- Science, Social --- Sciences, Social --- Social Science --- Psychoanalysis and social sciences --- Proxemics --- Behavioral Science --- Proxemic --- Science, Behavioral --- Sciences, Behavioral --- Psychiatrists --- Psychiatrist --- Psychodynamic Analysis --- Analyses, Psychodynamic --- Analysis, Psychodynamic --- Psychodynamic Analyses --- Sociology --- Factors, Psychological --- Psychological Factors --- Psychological Side Effects --- Psychologists --- Psychosocial Factors --- Side Effects, Psychological --- Factor, Psychological --- Factor, Psychosocial --- Factors, Psychosocial --- Psychological Factor --- Psychological Side Effect --- Psychologist --- Psychosocial Factor --- Side Effect, Psychological --- General Social Development and Population --- affirmative action. --- clear. --- dynamics of social existence. --- easy to understand. --- essays on psychoanalytic concepts. --- human social behavior. --- masculinity and violence. --- psychoanalytic approaches deepen sociological perspective. --- psychoanalytic theory. --- social structural and social psychological elements. --- sociology and psychoanalysis.