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Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail.Comprehensive protocols included for the study of* In vitro methods for studying neuroendocrine pulsatility* In vivo sampling and recording procedures for monitoring pulsatility in several species* Improved quantitative and analy

Paraneurons. --- Biological rhythms. --- Cell interaction. --- Cell-cell interaction --- Cell communication --- Cellular communication (Biology) --- Cellular interaction --- Intercellular communication --- Cellular control mechanisms --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Neuroendocrine cells --- Neurons --- Chromaffin cells --- Periodicity

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The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Circadian Rhythms contains an extensive discussion of genetic and biochemical aspects of circadian rhythms. In this volume organisms such as neurospora, bacteria, drosophila

Circadian rhythms. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Circadian rhythms --- Biological rhythms --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Behavior, Circadian --- Biological clocks, Daily --- Circadian behavior --- Circadian clocks --- Circadian cycles --- Clocks, Circadian --- Cycles, Circadian --- Daily activity cycles --- Daily biological clocks --- Diel cycles --- Diurnal rhythms --- Rhythms, Circadian --- Periodicity --- Chronobiology --- Cycles --- Pacemaker cells

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This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution. .

Evolutionary biology. --- Bioinformatics. --- Evolutionary Biology. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Data processing --- Molecular evolution. --- Biological rhythms. --- Biological clocks --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biochemical evolution --- Chemical evolution --- Life --- Molecular biology --- Periodicity --- Origin

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Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock fun

Biological Clocks. --- Cantatas, Secular. --- Chronobiology Disorders. --- Circadian rhythms. --- Human biology. --- Science fiction -- Songs and music. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Circadian rhythms --- Biological rhythms --- Behavior, Circadian --- Biological clocks, Daily --- Circadian behavior --- Circadian clocks --- Circadian cycles --- Clocks, Circadian --- Cycles, Circadian --- Daily activity cycles --- Daily biological clocks --- Diel cycles --- Diurnal rhythms --- Rhythms, Circadian --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Periodicity --- Chronobiology --- Cycles --- Pacemaker cells

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In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics.Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.

Biomathematics. Biometry. Biostatistics --- General biophysics --- Biological rhythms --- Mathematics --- Biological Clocks. --- Mathematics. --- Periodicity. --- 57.034 --- -Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biological Rhythms --- Bioperiodicity --- Cyclicity --- Rhythmicity --- Biological Rhythm --- Bioperiodicities --- Biorhythm --- Cyclicities --- Periodicities --- Rhythm, Biological --- Rhythmicities --- Mathematic --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Cyclic variations, oscillation. Rhythmicity. --- Periodicity --- Biological rhythms. --- -Cyclic variations, oscillation. Rhythmicity. --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Biological Clocks --- Biological clocks --- Cyclic variations, oscillation. Rhythmicity --- Biophysics --- Biophysique --- Biological rhythms - Mathematics --- Biological rhythms(Mathematical Study) --- Biomathematique --- Chaos