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Infertility, Male. --- Oxidative stress --- Pathophysiology. --- Oxidation-reduction reaction --- Stress (Physiology) --- Male infertility --- Male sterility --- Sterility, Male --- Generative organs, Male --- Infertility --- Diseases

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This unique textbook – the first of its kind – presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility. This hot topic is covered from a multitude of angles in seven thematic sections: origin and pathophysiology, clinical evaluation, medical and surgical therapy, controversies, pro and con debates, and clinical case scenarios. The scope of varicocele includes basic and transitional research, genetics, diagnostic testing with conventional and advanced molecular biology approaches, hormonal control, interventional therapy and assisted reproductive technology (ART). Repair of varicocele, which can be carried out by various methods, not only alleviates oxidative stress‐associated infertility but also prevents and protects against the progressive character of varicocele and its consequent upregulations of systemic oxidative stress. Even with the advances in the understanding of this intriguing disease and consensus on some areas such as diagnosis and pathophysiology, substantial controversy still exists, in particular concerning the benefits of treatment and to whom treatment should be offered. Additional chapters discuss, in depth, such controversies surrounding the role of varicocele in male infertility and present clinical case scenarios dealing with management of subclinical and clinical varicocele. A series of editorial comments is provided by the editors at the end of selected chapters, containing an objective and concise summary of the information from each chapter. In addition, chapters open up with key points for quick references and conclude with multiple choice questions and answers for immediate review and retention of the rich content. Generously illustrated, Varicocele and Male Infertility: A Complete Guide represents an invaluable tool for medical students in reproductive medicine as well as researchers and clinicians working in the field of infertility (e.g., urologists, gynecologists, reproductive endocrinologists, and embryologists) and is comprised of chapters written by leading and internationally recognized clinicians and scientists with expertise in varicocele, skillfully edited by leaders in the field.

Reproductive Medicine. --- Andrology. --- Generative organs, Male --- Human reproduction --- Men --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Endocrine aspects --- Diseases --- Physiology --- Health aspects --- Reproductive medicine. --- Varicocele. --- Infertility, Male. --- Male infertility --- Male sterility --- Sterility, Male --- Infertility --- Spermatic cord --- Varicose veins

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This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.

Medicine. --- Endocrinology. --- Reproductive medicine. --- Andrology. --- Medicine & Public Health. --- Reproductive Medicine. --- Infertility, Male --- Diagnosis --- Research --- Male infertility --- Male sterility --- Sterility, Male --- Generative organs, Male --- Infertility --- Diseases --- Internal medicine --- Hormones --- Human reproduction --- Men --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Endocrine aspects --- Physiology --- Health aspects --- Endocrinology . --- Reproductive health.

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The book aims to bring into focus the current understanding of male reproduction and the pathological basis of failure to reproduce in men. Infertility in men is a common disorder. However, attempts at scientific study of male infertility are of very recent origin. Many questions about the physiology and pathophysiology of male reproduction are still not clear. The chapters are written by authorities in the field with great clinical experience. The primary focus would be on clinical perspective; however emphasis would also be placed on basic research and molecular biology.  .

Reproductive medicine. --- Reproductive Medicine. --- Infertility. --- Male infertility --- Male sterility --- Medicine. --- Internal medicine. --- Urology. --- Medicine & Public Health. --- Internal Medicine. --- Infertility, Male. --- Sterility, Male --- Generative organs, Male --- Infertility --- Involuntary childlessness --- Sterility --- Sterility in humans --- Childlessness --- Generative organs --- Fertility, Human --- Sterilization (Birth control) --- Diseases --- Medicine --- Genitourinary organs --- Medicine, Internal --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Health aspects

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Male Infertility: Problems and Solutions provides a summary of state of the art developments in male infertility for both new and experienced practitioners. Written in a clear, concise and readable style, this volume allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include interpretation of semen analysis and advanced testing, endocrine and genetic evaluation, diagnosis of azoospermia as well as an up-to-date interpretation and analysis of the many new therapies available for the treatment of male factor infertility. Male Infertility: Problems and Solutions provides rapid acquisition of pertinent background and development of management plans through the use of concise discussion and treatment algorithms and thus will be of great value to general urologists, gynecologists, primary care providers and allied health providers who manage infertility in both men as well as women.

Infertility, Male -- Diagnosis. --- Infertility, Male -- Treatment. --- Infertility, Male. --- Infertility, Male --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Infertility --- Genital Diseases, Male --- Diagnosis --- Male Urogenital Diseases --- Diseases --- Medicine --- Health & Biological Sciences --- Urology & Nephrology --- Treatment. --- Male infertility --- Male sterility --- Sterility, Male --- Medicine. --- Reproductive medicine. --- Surgery. --- Urology. --- Medicine & Public Health. --- Reproductive Medicine. --- Generative organs, Male --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Health --- Surgery, Primitive --- Genitourinary organs --- Health aspects --- Reproductive health.