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Computational Biology. --- Non-coding RNA. --- Sequence Analysis, RNA. --- Analysis, RNA Sequence --- Determination, RNA Sequence --- Determinations, RNA Sequence --- RNA Sequence Determination --- RNA Sequence Determinations --- RNA Sequencing --- Sequence Determinations, RNA --- RNA Sequence Analysis --- Sequence Determination, RNA --- Analyses, RNA Sequence --- RNA Sequence Analyses --- Sequence Analyses, RNA --- Sequencing, RNA --- Molecular Sequence Annotation --- fRNA --- Functional RNA --- ncRNA --- nmRNA --- Non-messenger RNA --- Non-translated RNA --- Noncoding RNA --- Nontranslated RNA --- Small non-messenger RNA --- Small RNA --- snmRNA --- sRNA --- Untranslated RNA --- RNA --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Bioinformatics --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Computational Chemistry --- Genomics

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The storage, processing, description, transmission, connection, and analysis of the waves of new genomic data have made bioinformatics skills essential for scientists working with DNA sequences. In Bioinformatics for DNA Sequence Analysis, experts in the field provide practical guidance and troubleshooting advice for the computational analysis of DNA sequences, covering a range of issues and methods that unveil the multitude of applications and the vital relevance that the use of bioinformatics has today. Individual book chapters explore the use of specific bioinformatic tools, accompanied by practical examples, a discussion on the interpretation of results, and specific comments on strengths and limitations of the methods and tools. As a part of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Focused and cutting-edge, Bioinformatics for DNA Sequence Analysis serves molecular biologists, geneticists, and biochemists as an enriched task-oriented manual, offering step-by-step guidance for the analysis of DNA sequences in a simple but meaningful fashion.

Sequence Analysis, DNA --- Computational Biology --- Bioinformatics --- Nucleotide sequence --- Bio-informatique --- Génome humain --- methods --- Laboratory manuals --- Manuels de laboratoire --- Séquençage --- Methods --- Biology --- Sequence Analysis --- Investigative Techniques --- Genetic Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Biology - General --- Health & Biological Sciences --- Génome humain --- Séquençage --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Analysis, DNA Sequence --- DNA Sequence Determination --- DNA Sequence Determinations --- DNA Sequencing --- Determination, DNA Sequence --- Determinations, DNA Sequence --- Sequence Determinations, DNA --- DNA Sequence Analysis --- Sequence Determination, DNA --- Analyses, DNA Sequence --- DNA Sequence Analyses --- Sequence Analyses, DNA --- Sequencing, DNA --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Bio-informatics --- Biological informatics --- methods. --- Information science --- Computational biology --- Systems biology --- Nucleic acids --- Nucleotides --- Sequence alignment (Bioinformatics) --- Data processing --- Analysis --- Bioinformatics. --- Human genetics. --- Human Genetics. --- Heredity, Human --- Human biology --- Physical anthropology

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Comparative Genomics, Volume 1, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume I contains the first four of seven sections. In the first section, the reader is introduced to genomes via a number of visualization tools that allow one to browse through a particular genome of interest. The second and third sections deal with comparative analysis at the level of individual sequences, and present methods useful in sequence alignment, the discovery of conserved sequence motifs, and the analysis of codon usage. The fourth section deals with the identification and structural characterization of non-coding RNA genes — this class of genes is particularly difficult to predict, and discovery of these elements is almost completely reliant on comparative genomics. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 2 is also available from Humana Press.

Genomics --- Nucleotide sequence --- Methods --- Sequence Analysis --- Genetic Techniques --- Genetics --- Investigative Techniques --- Computational Biology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biology --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Health & Biological Sciences --- Methodology --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Bio-Informatics --- Biology, Computational --- Computational Molecular Biology --- Bioinformatics --- Molecular Biology, Computational --- Bio Informatics --- Bio-Informatic --- Bioinformatic --- Biologies, Computational Molecular --- Biology, Computational Molecular --- Computational Molecular Biologies --- Molecular Biologies, Computational --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Genome research --- Genomes --- methods --- Research --- Life sciences. --- Human genetics. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Biochemistry, general. --- Human Genetics. --- Cell Biology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Heredity, Human --- Human biology --- Physical anthropology --- Biosciences --- Science --- Composition --- Cytology. --- Genètica humana --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà

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After the generation of genome sequence data from a wide variety of plants, databases are filled with sequence information of genes with no known biological function, and while bioinformatics tools can help analyze genome sequences and predict gene structures, experimental approaches to discover gene functions need to be widely implemented. In Plant Reverse Genetics: Methods and Protocols, leading researchers in the field describe cutting-edge methods, both high-throughput and genome-wide, involving the models Arabidopsis and rice as well as several other plants to provide comparative functional genomics information. With chapters on the analysis of high-throughput genome sequence data, the identification of non-coding RNA from sequence information, the comprehensive analysis of gene expression by microarrays, and metabolomic analysis, the thorough methods of the book are fully supported by scripts to aid their computational use. Written in the highly successful Methods in Molecular Biology™ series format, the chapters contain introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and essential, Plant Reverse Genetics: Methods and Protocols is an ideal guide for researchers seeking an understanding of how the complex web of plant genes work together in a systems biology view.

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--- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Data Banks as Topic --- Data Bases as Topic --- Databanks as Topic --- DNA Databanks --- DNA Sequence Databases --- European Molecular Biology Laboratory Nucleotide Sequence Database --- Nucleic Acid Sequence Databases --- RNA Sequence Databases --- DDBJ --- DNA Data Bank of Japan --- DNA Data Banks --- DNA Databases --- Databases, DNA --- Databases, DNA Sequence --- Databases, Nucleic Acid Sequence --- Databases, RNA --- Databases, RNA Sequence --- EMBL Nucleotide Sequence Database --- GenBank --- Nucleic Acid Databases --- RNA Databases --- Bank, DNA Data --- Banks, DNA Data --- DNA Data Bank --- DNA Databank --- DNA Database --- DNA Sequence Database --- Data Bank, DNA --- Data Banks, DNA --- Databank, DNA --- Databanks, DNA --- Database, DNA --- Database, DNA Sequence --- Database, Nucleic Acid --- Database, RNA --- Database, RNA Sequence --- Nucleic Acid Database --- RNA Database --- RNA Sequence Database --- Sequence Database, DNA --- Sequence Database, RNA --- Sequence Databases, DNA --- Sequence Databases, RNA --- Plant --- Plant Genome --- Genomes, Plant --- Plant Genomes --- Analysis, Sequence --- Determination, Sequence --- Determinations, Sequence --- Sequence Determinations --- Sequence Determination --- Analyses, Sequence --- Sequence Analyses --- Plant Genes --- Gene, Plant --- Plant Gene --- Genetic Structure --- Structure, Genetic --- Structures, Genetic --- Component, Genome --- Components, Genome --- Genome Component --- Data Banks, Factual --- Data Bases, Factual --- Databanks, Factual --- Data Bank, Factual --- Data Base, Factual --- Databank, Factual --- Database, Factual --- Factual Data Bank --- Factual Data Banks --- Factual Data Base --- Factual Data Bases --- Factual Databank --- Factual Databanks --- Factual Database --- Factual Databases --- Plant genome --- Genetic Data Banks --- Genetic Data Bases --- Genetic Databanks --- Genetic Information Databases --- Genetic Databases --- Genetic Sequence Databases --- OMIM --- Online Mendelian Inheritance In Man --- Bank, Genetic Data --- Banks, Genetic Data --- Data Bank, Genetic --- Data Banks, Genetic --- Data Base, Genetic --- Data Bases, Genetic --- Databank, Genetic --- Databanks, Genetic --- Database, Genetic --- Database, Genetic Information --- Database, Genetic Sequence --- Databases, Genetic Information --- Databases, Genetic Sequence --- Genetic Data Bank --- Genetic Data Base --- Genetic Databank --- Genetic Database --- Genetic Information Database --- Genetic Sequence Database --- Information Database, Genetic --- Information Databases, Genetic --- Sequence Database, Genetic --- Sequence Databases, Genetic --- Research --- research. --- Botany. --- Medical genetics. --- Plant Sciences. --- Plant Genetics and Genomics. --- Gene Function. --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects --- Floristic botany --- Genomics. --- Botany --- Genome