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In 1941 the Food and Drug Administration approved the use of diethylstilbestrol (DES), the first synthetic chemical to be marketed as an estrogen and one of the first to be identified as a hormone disruptor-a chemical that mimics hormones. Although researchers knew that DES caused cancer and disrupted sexual development, doctors prescribed it for millions of women, initially for menopause and then for miscarriage, while farmers gave cattle the hormone to promote rapid weight gain. Its residues, and those of other chemicals, in the American food supply are changing the internal ecosystems of human, livestock, and wildlife bodies in increasingly troubling ways. In this gripping exploration, Nancy Langston shows how these chemicals have penetrated into every aspect of our bodies and ecosystems, yet the U.S. government has largely failed to regulate them and has skillfully manipulated scientific uncertainty to delay regulation. Personally affected by endocrine disruptors, Langston argues that the FDA needs to institute proper regulation of these commonly produced synthetic chemicals.

Endocrine disrupting chemicals --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- History. --- Government policy --- Endocrine Disruptors --- Environmental Exposure --- History, 20th Century --- History, 21st Century --- Adverse effects --- History

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Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human healthPresents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human healthOffers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations.--

Endocrine disrupting chemicals -- Health aspects. --- Endocrine disrupting chemicals. --- Endocrine toxicology. --- Endocrine disrupting chemicals --- Physiological Effects of Drugs --- Environmental Pollutants --- Pharmacologic Actions --- Toxic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Endocrine Disruptors --- Public Health --- Health & Biological Sciences --- Toxicology & Public Health --- Health aspects --- Health aspects. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants

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Animal behavior --- Animal communication. --- Endocrine disrupting chemicals. --- Endocrine aspects. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- Animal biocommunication --- Animal language --- Biocommunication, Animal --- Language learning by animals --- Animal behavioral endocrinology --- Animal hormone-behavior relationships --- Behavioral endocrinology, Animal --- Hormonal aspects of animal behavior --- Hormone-behavior relationships, Animal --- Interactions, Animal hormone-behavior --- Relationships, Animal hormone-behavior --- Endocrinology --- Hormonal aspects

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This volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics.

Ecotoxicology. --- Metabolic diseases. --- Pharmacology. --- Environmental chemistry. --- Metabolic Diseases. --- Pharmacology/Toxicology. --- Environmental Chemistry. --- Chemistry, Environmental --- Chemistry --- Ecology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Disorders of metabolism --- Metabolic diseases --- Metabolic disorders --- Metabolism, Disorders of --- Diseases --- Ecotoxicology --- Pollutants --- Pollution --- Environmental health --- Toxicology --- Physiological effect --- Metabolism --- Endocrine disrupting chemicals. --- Disorders. --- Disorders --- Treatment. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Biochemistry --- Physiology

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How toxic are the products we consume on a daily basis? Whether it's triclosan in toothpaste, formaldehyde in baby shampoo, endocrine disruptors in water bottles, or pesticides on strawberries, chemicals in food and personal care products are of increasing concern to consumers. This book chronicles how ordinary people try to avoid exposure to toxics in grocery store aisles using the practice of "precautionary consumption." Through an innovative analysis of environmental regulation, the advocacy work of environmental health groups, the expansion of the health-food chain Whole Foods Market, and interviews with consumers, Norah MacKendrick ponders why the problem of toxics in the U.S. retail landscape has been left to individual shoppers-and to mothers in particular. She reveals how precautionary consumption, or "green shopping," is a costly and time-intensive practice, one that is connected to cultural ideas of femininity and good motherhood but is also most available to upper- and middle-class households. Better Safe Than Sorry powerfully argues that precautionary consumption places a heavy and unfair burden of labor on women and does little to advance environmental justice or mitigate risk.

Consumer goods --- Product safety --- Women consumers --- Consumer behavior --- Safety measures. --- Psychology. --- avoiding exposure to toxins. --- chemicals in food. --- consumer concern. --- endocrine disruptors. --- environmental health groups. --- environmental justice. --- environmental regulation. --- female labor. --- formaldehyde. --- grocery stores. --- health food. --- individual shoppers. --- personal care products. --- poison. --- precautionary consumption. --- retail landscape. --- triclosan. --- unfair burden. --- united states. --- whole foods market.