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Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level from a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance. Combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making it essential to understand for multiple therapy options.
Breast --- Cancer --- Treatment. --- Triple Negative Breast Neoplasms --- Drug Therapy, Combination --- therapy
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"Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches."--
Drug delivery systems. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Delivery systems --- Chemotherapy. --- Chemotherapy, Combination. --- Drug resistance --- Drug Delivery Systems --- Drug Therapy, Combination --- Drug Synergism --- Drug Resistance --- Prevention.
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Neuropathology --- Toxicology --- Pharmacology --- Nervous system --- Drug Therapy --- Poisoning --- Système nerveux --- Toxicologie --- Drug effects --- adverse effects --- Diseases --- Maladies --- Neurotoxicology. --- Pharmacology. --- Drug therapy --- Poisoning. --- Drug effects. --- Adverse effects. --- Système nerveux --- Diseases. --- Nervous System --- drug effects. --- Drug-Related Side Effects and Adverse Reactions. --- Neurotoxicology --- Drug Therapy, Combination
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Induction chemotherapy, as part of an integrated plan of management for locally advanced cancers, is being practised throughout the world in independent, isolated departments in universities, teaching hospitals, and clinical schools. Frequently, however, teams are relatively unaware of the work being undertaken in other institutions, and this situation may slow further progress. This book aims to present the full range of management techniques and practices used in induction chemotherapy within one accessible volume. It provides up-to-date information on the pioneering and cutting edge practices employed in different institutions and documents the advantages of integrated treatment schedules. Patient selection is discussed, and each of the cancer types for which induction therapy has proved important is considered in detail. All who are responsible for the treatment of patients with locally advanced cancers will find this book to be an invaluable source of information. It will be particularly interesting for specialist oncologists aiming to set up and develop fully comprehensive cancer centres and for health administrators wishing to learn about the benefits of establishing such centres in strategic locations.
Cancer -- Chemotherapy. --- Cancer -- Treatment. --- Chemotherapy. --- Infusions, Parenteral --- Therapeutic Uses --- Diseases --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Drug Administration Routes --- Pharmacologic Actions --- Drug Therapy --- Chemical Actions and Uses --- Chemicals and Drugs --- Infusions, Intra-Arterial --- Remission Induction --- Neoplasms --- Antineoplastic Agents --- Medicine --- Health & Biological Sciences --- Oncology --- Chemotherapy, Combination. --- Cancer --- Drug therapy --- Pharmacotherapy --- Combination chemotherapy --- Combination drug therapy --- Drug therapy, Combination --- Polychemotherapy --- Medicine. --- General practice (Medicine). --- Oncology. --- Medicine & Public Health. --- General Practice / Family Medicine. --- Antineoplastic agents --- Drugs --- Pharmacology --- Treatment --- Oncology . --- Family medicine. --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Tumors
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Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDRTB) increasingly occur in resource-constrained settings. In the context of a national response to MDR- and XDR-TB, health workers in TB clinics (in district hospitals and some accredited health centres) will need to diagnose MDR-TB, initiate second-line anti-TB drugs, and monitor MDR-TB treatment. This field guide was created to help health workers carry out these tasks. It is a job aid that medical officers and TB nurses are meant to use frequently during the day for quick reference. It is based on the 2
Antitubercular agents. --- Multidrug-resistant tuberculosis. --- Practice Guideline. --- Multidrug-resistant tuberculosis --- Antitubercular agents --- Immunologic Deficiency Syndromes --- Tuberculosis --- Lentivirus Infections --- Therapeutics --- Sexually Transmitted Diseases, Viral --- Anti-Bacterial Agents --- Guideline --- Drug Therapy, Combination --- HIV Infections --- Practice Guideline --- Antiretroviral Therapy, Highly Active --- Drug Therapy --- Tuberculosis, Multidrug-Resistant --- Antitubercular Agents --- Sexually Transmitted Diseases --- Anti-Infective Agents --- Immune System Diseases --- Mycobacterium Infections --- Publication Formats --- Retroviridae Infections --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Therapeutic Uses --- Actinomycetales Infections --- Virus Diseases --- Diseases --- RNA Virus Infections --- Publication Characteristics --- Gram-Positive Bacterial Infections --- Pharmacologic Actions --- Bacterial Infections --- Chemical Actions and Uses --- Chemicals and Drugs --- Bacterial Infections and Mycoses --- Medicine --- Infectious Diseases --- Health & Biological Sciences --- Drugs, Antitubercular --- Tuberculostatic agents --- MDR-TB (Multidrug-resistant tuberculosis) --- MDR tuberculosis --- Polydrug-resistant tuberculosis --- Antibacterial agents --- Drug resistance in microorganisms --- Multidrug resistance --- Chemotherapy
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Pharmacology. Therapy --- Drug Antagonism --- Drug Synergism --- Drug Therapy --- Drug interactions --- Drugs --- Médicaments --- adverse effects --- Toxicology --- Interaction --- Toxicologie --- Drug Antagonism. --- Drug Synergism. --- Drug-Related Side Effects and Adverse Reactions. --- -Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Interactions, Drug --- Drug Augmentation --- Drug Potentiation --- Augmentation, Drug --- Augmentations, Drug --- Drug Augmentations --- Drug Potentiations --- Drug Synergisms --- Potentiation, Drug --- Potentiations, Drug --- Synergism, Drug --- Synergisms, Drug --- Drug Combinations --- Drug Therapy, Combination --- Antagonism, Drug --- Antagonisms, Drug --- Drug Antagonisms --- Pharmaceutical Preparations --- Polypharmacy --- Side effects --- antagonists & inhibitors --- Drug interactions. --- Toxicology. --- -Toxicology --- Médicaments --- Drug-Related Side Effects and Adverse Reactions --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Drug toxicity --- toxicity
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The emergence in 2006 of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, are serious threats to global public health and jeopardizes efforts to effectively control the disease. These important developments and the availability of new evidence related to the diagnosis and management of drug-resistant tuberculosis have mandated an urgent update of existing guidelines. Guidelines for the programmatic management of drug-resistant tuberculosis: emergency updated edition 2008 replaces previous publications by the Wor
Antitubercular agents. --- Multidrug-resistant tuberculosis -- Chemotherapy. --- Multidrug-resistant tuberculosis -- Prevention. --- Multidrug-resistant tuberculosis --- Antitubercular agents --- HIV infections --- Comorbidity --- Highly active antiretroviral therapy --- Sexually Transmitted Diseases, Viral --- Tuberculosis --- Immunologic Deficiency Syndromes --- Drug Therapy, Combination --- Lentivirus Infections --- Anti-Bacterial Agents --- Therapeutics --- Immune System Diseases --- Retroviridae Infections --- Anti-Infective Agents --- Mycobacterium Infections --- Sexually Transmitted Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Therapeutic Uses --- Actinomycetales Infections --- RNA Virus Infections --- Virus Diseases --- Diseases --- Gram-Positive Bacterial Infections --- Pharmacologic Actions --- Chemical Actions and Uses --- Bacterial Infections --- Chemicals and Drugs --- Bacterial Infections and Mycoses --- HIV Infections --- Drug Therapy --- Tuberculosis, Multidrug-Resistant --- Antitubercular Agents --- Antiretroviral Therapy, Highly Active --- Public Health --- Health & Biological Sciences --- Communicable Diseases --- Chemotherapy --- Prevention --- Treatment --- Highly active antiretroviral therapy. --- Treatment. --- Chemotherapy. --- Prevention. --- MDR-TB (Multidrug-resistant tuberculosis) --- MDR tuberculosis --- Polydrug-resistant tuberculosis --- HIV (Viruses) infections --- HTLV-III infections --- HTLV-III-LAV infections --- Human T-lymphotropic virus III infections --- Antiretroviral therapy, Highly active --- HAART (Chemotherapy) --- Coexisting disease --- Coexisting illness --- Drugs, Antitubercular --- Tuberculostatic agents --- Drug resistance in microorganisms --- Multidrug resistance --- Lentivirus infections --- Sexually transmitted diseases --- Chemotherapy, Combination --- Epidemiology --- Antibacterial agents
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Drug Antagonism. --- Drug Synergism. --- Drug-Related Side Effects and Adverse Reactions. --- Drug Interactions. --- Drug interactions --- Drugs --- -#GBIB:CBMER --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Interactions, Drug --- Drug Interaction --- Interaction, Drug --- Metabolic Detoxication, Phase I --- Drug-Related Side Effects and Adverse Reactions --- Metabolic Side Effects of Drugs and Substances --- Drug Augmentation --- Drug Potentiation --- Augmentation, Drug --- Augmentations, Drug --- Drug Augmentations --- Drug Potentiations --- Drug Synergisms --- Potentiation, Drug --- Potentiations, Drug --- Synergism, Drug --- Synergisms, Drug --- Drug Combinations --- Drug Therapy, Combination --- Antagonism, Drug --- Antagonisms, Drug --- Drug Antagonisms --- Pharmaceutical Preparations --- Polypharmacy --- Toxicology --- Side effects --- antagonists & inhibitors --- Drug interactions. --- Toxicology. --- Drug Antagonism --- Drug Interactions --- Drug Synergism --- #GBIB:CBMER --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Contraindications, Drug --- Clinical Trials, Phase IV as Topic --- Drug toxicity --- adverse effects --- toxicity
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