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Biodegradation. --- Biotransformation (Metabolism) --- Organic compounds --- Biodégradation --- Biotransformation (Métabolisme) --- Biodegradation --- Composé organique --- organic compounds --- Contamination chimique --- Chemical contamination --- Détoxification --- Detoxification --- Micro-organisme --- microorganisms --- Propriété des micro-organismes --- Microbial properties --- Biotransformation (Metabolism). --- Biodégradation --- Biotransformation (Métabolisme) --- Detoxification. --- Organic compounds - Biodegradation

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Detoxification (Substance abuse treatment) --- Popular works --- Alcohol --- Physiological effect --- Hangover cures

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Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as untapped cocktails of biologically active compounds that are being increasingly recognized as a new emerging source of peptide-based therapeutics. Venomous animals are considered to be specialized predators that have evolved the most sophisticated peptide chemistry and neuropharmacology for their own biological purposes by producing venoms that contain a structural and functional diversity of neurotoxins. These neurotoxins appear to be highly selective ligands for a wide range of ion channels and receptors. Therefore, they represent interesting lead compounds for the development of analgesics, anti-cancer drugs, drugs for neurological disorders such as multiple sclerosis, Parkinson' s disease, Alzheimer' s disease, and other therapeutics. This Special Issue of Toxins aims to provide a comprehensive look at toxins and toxin-inspired leads and will focus on the mechanisms of action, structure-function relationships, and evolution of pharmacologically interesting venom components, including the most recent developments related to the emergence of venoms as an underutilized source of highly evolved bioactive peptides with clinical potential.

Toxins. --- Natural toxicants --- Toxicants, Natural --- Toxins and antitoxins --- Antigens --- Metabolites --- Poisons --- Antitoxins --- Detoxification (Health)

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Toxins are biologically active substances produced by most kinds of living organisms, bacteria, fungi, plants, and animals. They present a vast diversity of molecular structures and target a wide variety of receptors involved in a range of physiological processes. As toxins are selected during evolution to acquire/improve their disabling/lethal effects, they display finely tuned functional properties often associated with high affinities and selectivity. Moreover, toxins are valuable tools to unravel cellular processes due to their extreme specificity for cell surface and/or intracellular targets. Therefore, toxins are very attractive compounds because of their Janus-like character; while they mostly act as deadly poisons like monstrous Mr. Hyde, they can also be tamed into good remedies like admirable Dr. Jekyll. As such, they have been primarily investigated not only for the light they can throw on fundamental physiological processes but also for their potential therapeutic applications. This book, emerging from the 27th Annual Meeting of the French Society of Toxinology (SFET, http:sfet.asso.fr/international), will be of great interest for those in the scientific community who want to know more about the fascinating world of toxins.

Toxins. --- Natural toxicants --- Toxicants, Natural --- Toxins and antitoxins --- Antigens --- Metabolites --- Poisons --- Antitoxins --- Detoxification (Health)

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Proefschriften --- Thèses --- Eau souterraine --- groundwater --- Pollution de l'eau --- Water pollution --- Pollution du sol --- Soil pollution --- Hydrocarbure --- Hydrocarbons --- Détoxification --- Detoxification --- Propriété des micro-organismes --- Microbial properties --- PCR --- Écologie microbienne --- microbial ecology --- Bacteria --- Identification --- identification --- Génotype --- genotypes --- Surveillance --- monitoring --- Theses --- Detoxification. --- identification.