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This dissertation by Johan Zötterman explores the use of Laser Speckle Contrast Imaging (LSCI) in reconstructive surgery. It investigates the technology's application for non-invasive tissue perfusion monitoring, comparing it to other methods like Laser Doppler Flowmetry (LDF). Through various studies, the research evaluates LSCI's effectiveness in detecting venous outflow obstruction and predicting flap necrosis in surgical procedures. The work highlights LSCI's advantages, such as fast acquisition time and spatial resolution, while acknowledging limitations like sensitivity to motion artifacts and inability to provide absolute perfusion data. The dissertation is intended for medical professionals and researchers interested in advanced imaging techniques for surgical applications.
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