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Veterinary vaccines. --- Veterinary vaccines --- Technological innovations.

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"Both a theoretical text and a practical handbook, Vaccines for Veterinarians is the first of its kind to bring the basic science of animal vaccination and the practical details of vaccine use together in one single volume. From the first chapter on the history of vaccination and the triumph of rinderpest eradication to the last chapter on the rapidly emerging field of cancer vaccines, this book offers a truly comprehensive grounding in established and emerging vaccines for both major and minor species. Specific topics include viral vectored vaccines, DNA-plasmid vaccines, RNA vaccines, reverse vaccinology, the complexities of adjuvant use, vaccine failures and adverse events, vaccine production and regulation, robotic vaccination machines, contraceptive and production-enhancing vaccines, and so much more. At a time when resistance to human vaccination is receiving much publicity, this evidence-based book is the ideal counter to ill-informed speculation - serving as a timely reminder that vaccination is essential for the control of infectious diseases in animals." -- Provided by publisher.

Veterinary medicine --- Vaccines. --- Veterinary vaccines. --- Veterinary Medicine. --- Vaccination --- Vaccins vétérinaires --- Vaccination des animaux --- veterinary.

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The two most prominent mycobacterial diseases in animals include bovine tuberculosis, caused by Mycobacterium bovis and Johne’s disease, caused by Mycobacterium avium subspecies paratuberculosis. Erradication of both diseases has been hampered by a variety of factors. In many countries, the persistence of tuberculosis in cattle has been attributed to reservoirs of M. bovis in wildlife species. Brushtail possums, deer and badgers are notable examples of wildlife reservoirs for M. bovis. The difficulties in eliminating the wildlife reservoir for M. bovis further suggest the need for vaccination of farmed livestock. Vaccination of wildlife species has also been attempted with mixed results. Delivery of the vaccine to wildlife species appears to be a chief obstacle. Vaccination itself leads to complications for diagnostics. For example, when cattle are vaccinated with both BCG and a commercial Johne’s vaccine there is a biased toward the avian tuberculin skin test reaction. Despite these issues, BCG seems to be the clear standard for vaccination against M. bovis, yet many laboratories are investigating ways to improve on BCG. For Johne’s disease, the available commercial vaccines consist of whole-cell preparations in one form or another. But with the ability to generate directed knockouts of specific genes, a number of defined mutants have been constructed in a few laboratories. These should be tested and directly compared with each other and alongside commercial vaccine formulations to determine not only which vaccine is most protective, but which animal model is best for predicting protection in the target host. To this end, there has been a nation-wide, multi-institutional effort to test the best live, attenuated vaccine against Johne's disease in cattle, sheep and goats. This vaccine trial has spanned six years and was conducted in three phases. The first phase examined attenuation in bovine macrophages, the second phase was colonization of spleen and liver in mice and the third phase was protection from bacterial challenge in goats. Many new ideas and retrospective approaches have emerged from this unprecedented effort. These aspects will be captured in this Research Topic. In this Research Topic, we will seek articles on these above topics, but other issues surrounding vaccination of animals against mycobacteria will also be explored. These include immune parameters, correlates of protection, adjuvants and other vaccine formulations, etc.

Veterinary vaccines. --- Bacterial vaccines. --- Tuberculosis in cattle --- Bacterial Vaccines --- Prevention. --- immunology. --- goat trial --- correlates of protection --- Paratuberculosis --- Johne's disease --- Attenuated mutant --- Vaccine

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This book provides an in-depth explanation of the advantages and current limitations of recombinant plant-made vaccines for use in veterinary medicine, including for livestock, pets, and wild animals. Written by top scientists in the field, it discusses the background to and latest scientific advances in plant-made vaccines for the most commonly targeted veterinary infections. With the recent high-profile research into recombinant plant-made therapeutics for Ebola and Zika viruses, it is likely that the products will be commercialized and widely used in the future. Plant-made therapeutics have a variety of advantages over those made in traditional systems; however, their most fruitful application may be in veterinary medicine, due to less stringent regulations and a greater need for low-cost products.

Medicine. --- Vaccines. --- Biomedical engineering. --- Agriculture. --- Biomedicine. --- Vaccine. --- Veterinary Medicine/Veterinary Science. --- Biomedical Engineering/Biotechnology. --- Veterinary vaccines. --- Veterinary medicine. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Animal health --- Animals --- Domestic animals --- Livestock --- Biologicals --- Diseases --- Losses