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Electronic prescribing (EP) is a complex discipline, the success of which relies on the successful interplay of system design, data support and clinical practice. It represents the use of electronic systems to facilitate and enhance communication of a prescription or medicine order, and improves legibility and completeness of prescriptions, improves availability of electronic decision support tools at the point of prescribing, enables a comprehensive audit trail, and reduces medication-related errors. These benefits are far-reaching in significance, both in terms of their effects on risk management and risk reduction and their financial impact. Given the likely growth of interest in electronic medicines management, this discussion of relevant design issues and their impact is timely. Electronic Prescribing: Principles and Practice discusses the basic principles of the design and implementation of secondary care electronic medicine management systems, and how they impact hospital workflow and clinical practice. It documents the key aspects of EP systems for use in secondary care, including design issues, data support, benefits and the ways in which electronic medicines management systems can optimize clinical and professional practice.Because of the significance of electronic medicines management to the whole medical supply chain, and the various stakeholders involved in the IT implementations, the book will be of interest to a wide range of professionals, from hospital pharmacists and prescribing physicians to health system managers and informaticians.
Medicine & Public Health. --- Health Informatics. --- Medicine/Public Health, general. --- Public Health/Gesundheitswesen. --- General Practice / Family Medicine. --- Nursing. --- Medicine. --- Family medicine. --- Medical records --- Médecine --- Médecine familiale --- Dossiers médicaux --- Soins infirmiers --- Data processing. --- Informatique --- Drugs --Prescribing --Data processing. --- Drugs --- Medical Order Entry Systems --- Electronic Prescribing --- Medical Records Systems, Computerized --- Hospital Information Systems --- Prescriptions --- Management Information Systems --- Pharmaceutical Services --- Information Systems --- Hospital Administration --- Medical Records --- Organization and Administration --- Medical Informatics Applications --- Records as Topic --- Health Services --- Health Services Administration --- Medical Informatics --- Health Care Facilities, Manpower, and Services --- Health Care --- Information Science --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Data processing --- Prescribing --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- General practice (Medicine). --- Public health. --- Health informatics. --- Public Health. --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Clinical nursing --- Nurses and nursing --- Nursing process --- Care of the sick --- Medicine --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Medical care --- Health Workforce --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Clinical informatics --- Health informatics --- Medical information science --- Information science
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Polypharmacy is a necessary and important aspect of drug treatment; however, it becomes a challenge when the medication risks outweigh the benefits for an individual patient. Drug–drug interactions and the introduction of prescribing cascades are common features of polypharmacy, which can lead to ineffectiveness and increased risk of adverse drug reactions (ADR). Genes encoding CYP450 isozymes and other drug-related biomarkers have attracted considerable attention as targets for pharmacogenetic (PGx) testing due to their impact on drug metabolism and response. This Special Issue is devoted to explore the status and initiatives taken to circumvent ineffectiveness and to improve medication safety for polypharmacy patients. Specific areas include drug–drug interactions and consequences thereof in therapeutic management, including PK- and PD-profiling; the application of PGx-based guidance and/or decision tools for drug–gene and drug–drug gene interactions; medication reviews; development and application of deprescribing tools; and drivers and barriers to overcome for successful implementation in the healthcare system.
acute kidney injury --- early biomarker --- plasma neutrophil gelatinase-associated lipocalin --- soluble urokinase plasminogen activator receptor --- medication optimization --- older patients --- emergency department --- multimorbidity --- polypharmacy --- potentially inappropriate medication use --- older adults --- prevalence --- determinants --- chronic --- outpatient --- 2019 Beers criteria --- Ethiopia --- pharmacogenomics --- persons with diabetes --- drug–drug interactions --- drug–gene interactions --- cytochrome P450 --- SLCO1B1 --- drug interaction checkers --- adverse drug reactions --- pharmacogenetics --- personalized medicine --- phenprocoumon --- DOACs --- bleeding --- thromboembolism --- HLA --- drug hypersensitivity --- abacavir --- allopurinol --- flucloxacillin --- antiepileptic drugs --- cost-effectiveness --- shared medication record --- medication reconciliation --- drug information service --- hospital pharmacy service --- electronic prescribing --- electronic medical record --- clinical pharmacist --- CYP2D6 --- CYP2D7P --- CYP2D8P --- copy number variation --- CNV --- genotyping --- 5’nuclease assay --- HRM --- high resolution melting --- drug metabolization --- extracellular vesicles --- exosomes --- microvesicles --- pharmacogene expression --- medication review --- deprescriptions --- quality of life --- aged --- aged, 80 and over --- nursing homes --- deprescribing --- medication-based risk score --- health outcomes --- cytochromes --- CYP1A2 --- adverse drug reaction --- antipsychotics --- olanzapine --- clozapine --- loxapine --- children --- youth --- digital decision-support --- health services research --- general practice --- process evaluation --- antidepressants --- utility --- population-based --- appropriateness --- medication adherence --- digital health
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