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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
Authors: --- --- ---
Year: 2022 Publisher: Basel MDPI Books

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Abstract

This collection of articles provides an overview of the current and future methods for applying a personalized medicine approach to the diagnosis, management, and treatment of autism spectrum disorder.

Keywords

fecal metabolites --- ASD --- microbiome --- gastrointestinal symptoms --- Fisher Discriminant Analysis --- digital biomarkers --- wearables --- time series analysis --- autism --- social dyads --- socio-motor parameters --- network connectivity --- non-linear complex dynamics --- stochastic analysis --- autism spectrum disorders --- copy number variants --- females --- Array-Comparative Genomic Hybridization (Array-CGH) --- autism spectrum disorder --- Ehlers-Danlos syndrome --- hypermobility spectrum disorders --- autonomic disorder --- mast cell activation syndrome --- genetic testing --- chromosomal microarray analysis --- whole exome sequencing --- whole genome sequencing --- clinical utility --- polygenic risk scores --- Temple Grandin --- biomarker --- omics --- precision medicine --- proteomics --- transcriptomics --- epigenetics --- metabolomics --- patient stratification --- mitochondria --- oxidative stress --- prenatal environment --- immune dysfunction --- immunoglobulin G --- intravenous immunoglobulin --- energy metabolism --- fatty acid oxidation --- acyl-carnitines --- resveratrol --- integrative --- model --- concomitant --- condition --- disorder --- autism spectrum disorder (ASD) --- genomics --- personalized treatment strategy --- single nucleotide polymorphisms --- clinical decision support tool --- ADHD --- PANDAS --- OCD --- anxiety --- folate receptor alpha --- folates --- pregnancy --- brain development --- fetal development --- cobalamin --- glutathione --- methylation --- methylcobalamin --- redox metabolism --- locked-in network syndrome --- resting-state functional magnetic resonance imaging --- temporal lobe epilepsy --- amygdala --- brain --- COVID-19 --- children --- cytokines --- flavonoids --- inflammation --- luteolin --- mast cells --- microglia --- SARS-CoV-2 --- stress --- nutraceuticals --- survey --- vitamins --- minerals --- B12 --- folinic acid --- quality of life --- parents --- intervention --- systematic review --- medical claims --- logistic regression analysis --- retrospective analysis --- associated risk --- monoamine neurotransmitters --- neurotransmitter deficiency --- cerebral folate deficiency --- folate receptor alpha autoantibodies --- leucovorin --- α-amylase --- cortisol --- heart rate variability --- neuromodulation --- sleep anxiety --- transdermal electrical neuromodulation --- neurostimulation --- n/a

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