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Phytochemicals --- SCIENCE / Life Sciences / Biochemistry. --- Himalaya Mountains.

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This edited volume describes cell-SELEX as the fundamental tool used to generate aptamer molecules for a wide range of applications in molecular medicine, bioanalysis and chemical biology. Easily integrated into the natural heterogeneous cell matrix, aptamers can be effectively used in theranostics, bioanalysis, environment detection and biomedical studies. The book gathers reviews that reflect the latest advances in the field of aptamers, and consists in fourteen chapters demonstrating essential examples of these aptamers and aptamer-nanomaterial assemblies, depending on the types of applications and biological systems. It also includes a separate chapter on the utilization of aptamers in real clinics and what will be required to achieve this significant goal. The book will be both appealing and useful to a broad audience, including biologists, bioscientists, and clinicians whose interests range from chemistry and biomedical engineering to cell and molecular biology and biotechnology. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V.T. and Louis Jackson Professor of Chemistry at the University of Florida, USA. Xiaohong Fang is a Professor at the Institute of Chemistry, Chinese Academy of Sciences, China.

Chemistry. --- Biotechnology. --- Molecular Medicine. --- Cancer Research. --- Nucleic Acid Chemistry. --- Oncology. --- Medicine. --- Nucleic acids. --- Chimie --- Cancérologie --- Médecine --- Biotechnologie --- Acides nucléiques --- Nucleic acids -- Biotechnology. --- Nucleic Acids -- chemistry -- Congresses. --- Oligonucleotides. --- SCIENCE / Life Sciences / Biochemistry. --- Mechanical Engineering --- Engineering & Applied Sciences --- Bioengineering --- Cancer --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy --- Cancer research. --- Molecular biology. --- Polynucleotides --- Biomolecules --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Chemical engineering --- Genetic engineering --- Health Workforce --- Cancer research --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology

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Gene function annotation has been a central question in molecular biology. The importance of computational function prediction is increasing because more and more large scale biological data, including genome sequences, protein structures, protein-protein interaction data, microarray expression data, and mass spectrometry data, are awaiting biological interpretation. Traditionally when a genome is sequenced, function annotation of genes is done by homology search methods, such as BLAST or FASTA. However, since these methods are developed before the genomics era, conventional use of them is not necessarily most suitable for analyzing a large scale data. Therefore we observe emerging development of computational gene function prediction methods, which are targeted to analyze large scale data, and also those which use such omics data as additional source of function prediction. In this book, we overview this emerging exciting field. The authors have been selected from 1) those who develop novel purely computational methods 2) those who develop function prediction methods which use omics data 3) those who maintain and update data base of function annotation of particular model organisms (E. coli), which are frequently referred.

Proteomics. --- Recombinant proteins. --- SCIENCE -- Life Sciences -- Biochemistry. --- Biochemistry --- Amino Acids, Peptides, and Proteins --- Genetics --- Biology --- Biological Science Disciplines --- Chemicals and Drugs --- Chemistry --- Natural Science Disciplines --- Disciplines and Occupations --- Genomics --- Proteomics --- Proteins --- Computational Biology --- Health & Biological Sciences --- Molecular biology. --- Structures. --- Molecular biochemistry --- Molecular biophysics --- Proteids --- Medicine. --- Biotechnology. --- Biochemistry. --- Bioinformatics. --- Biomedicine. --- Biomedicine general. --- Biochemistry, general. --- Biophysics --- Biomolecules --- Systems biology --- Polypeptides --- Chemical engineering --- Genetic engineering --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Molecular biology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Medical sciences --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Data processing --- Composition --- Health Workforce --- Biomedicine, general.